Current Scenario in Associating Clinical COVID-19 Biomarkers for Developing Surveillance Platforms.

The novel coronavirus that caused the epidemic and pandemic resulting in the acute respiratory illness known as coronavirus disease 2019 (COVID-19) has plagued the world. This is unlike other coronavirus outbreaks that have occurred in the past, such as Middle East respiratory syndrome (MERS) or severe acute respiratory syndrome (SARS). COVID-19 has spread more quickly and posed special challenges due to the lack of appropriate treatments and vaccines.

Exploring the separation, characterization and antioxidant activity of proteins and peptides from selected seagrasses in Palk Bay region of Tamil Nadu in India.

In this study, five seagrass species Halodule uninervis, Thalassia hemprichii, Enhalus acoroides, Cymodocea serrulata, and Syringodium isoetifolium collected from the Mandapam coastal region of Rameswaram (Palk Bay region), Tamil Nadu, India, were selected to identify the antioxidant-rich proteins/peptides. The primary objective was to identify the proteins/peptides present in these seagrass filtrates extracted by using four different pH-based buffer extracts and to assess their antioxidant activity. Among the various buffer extracts, 0.

Utilizing perfusion index for early identification of circulatory shock in neonates.

Introduction: Neonatal circulatory shock poses a significant challenge in intensive care settings and necessitates early recognition and intervention to prevent adverse outcomes. The perfusion index (PI), derived from pulse oximetry signals, is a potential adjunct tool for assessing peripheral perfusion and predicting shock in neonates. This prospective observational study aimed to evaluate the correlation between PI and circulatory shock in neonates with the goal of establishing PI as an objective parameter for early shock identification.

Etiological factors and management of vertigo - a retrospective study.

Introduction: Vertigo and dizziness are symptoms of various underlying conditions, ranging from benign to severe, affecting up to 40% of adults. Understanding the etiological factors and demographic characteristics associated with these symptoms is crucial for improving diagnostic accuracy and management. This study aims to identify the etiological factors contributing to vertigo and dizziness in a clinical setting and assess the effectiveness of treatment strategies.

Sexual and reproductive health considerations in the care of young adults with inflammatory bowel disease: A multidisciplinary conversation.

The effects of inflammatory bowel disease (IBD) and the medications used to treat it on sexual and reproductive health can be significant, impacting the quality of life of patients across gender identities. This article presents insights from a roundtable discussion facilitated by the Crohn's and Colitis Young Adults Network (CCYAN) between young adult patients with IBD and medical professionals, including physicians, nurses, psychologists, and trainees/medical students. It underscores the distinction between sexual and reproductive health, emphasizing the need to address both aspects comprehensively.

On three species of the genus Habrocestum Simon, 1876 (Araneae: Salticidae: Hasariini) from India.

Two new species of the ground-dwelling jumping spider genus Habrocestum Simon, 1876 from the wet evergreen forests of the southern Western Ghats, India are described: H. benjamin sp. nov.

An evaluation study on screening, partial purification, and characterization of proteins and antioxidant peptides from two varieties of Clitoria Ternatea.

This study focused on the unexplored bioactive proteins derived from the flower of Clitoria ternatea. The profiling of blue and white C. ternatea flowers was compared.

Ag@WO core-shell nanocomposite for wide range photo detection.

This study successfully synthesized high-performance photodetectors based on Ag-WO3 core-shell heterostructures using a simple and economical two-step pulsed laser ablation in water method and has investigated the electrical characteristics of the Ag@WO3 nanocomposite heterojunction. The Hall effect tests indicate that the synthesized Ag@WO exhibits n-type conduction with a Hall mobility of 1.25 × 10 cmVS.

C-Reactive Protein Biosensor for Diagnosing Infections Caused by Orthopedic Trauma.

Introduction: Infections linked to orthopedic trauma are common complications that place a significant strain on the healthcare system. Immediate identification of the infection and its severity is essential for providing effective treatment.

Method: C-reactive Protein (CRP) is a commonly used inflammatory marker in orthopedic surgery and has proven to be a valuable biomarker for diagnosing and monitoring infections.

ZIF-67 derivatives of NiCoS Decorated in Salen-Complex Amine Functionalization GO Layers for High-Performance Applications in Supercapacitor Devices.

The study develops polyamine-functionalized graphene oxide-supported NiCoS nanomaterial using a metal-organic framework (MOF). This modification adds free amines and oxygen functionality to the graphene oxide electrode surface, resulting in the decrease in the 2 theta value from 11.2 to 7.

Designing potential lead compounds targeting aminoglycoside N (6')-acetyltransferase in Serratia marcescens: A drug discovery strategy.

Serratia marcescens is an opportunistic human pathogen that causes urinary tract infections, ocular lens infections, and respiratory tract infections. S. marcescens employs various defense mechanisms to evade antibiotics, one of which is mediated by aminoglycoside N-acetyltransferase (AAC).

Exploring the potential therapeutic benefits of 7-methoxy coumarin for neuropathy pain: an in vivo, in vitro, and in silico approach.

Back Ground: 7-Methoxycoumarin (7-MC) is well recognized for its anti-inflammatory and anti-nociceptive actions. Its capacity to lessen neuropathic pain hasn't been documented yet. Hence the impact of 7-MC on vincristine-induced peripheral neuropathic pain in rodents was investigated.

Enhancing Airway Management: A Comparative Study of Macintosh and TAS Scope in Difficult Intubations.

Background: Intubation is essential in anesthesia for patient safety, requiring accurate techniques for difficult airways. Achieving first-attempt success is crucial. This study evaluates traditional laryngoscopes, such as the Macintosh, versus advanced tools like the TAS Scope.

Synthesis and Characterization of Multifunctional Chitosan-Silver Nanoparticles: An In-Vitro Approach for Biomedical Applications.

Antibiotics are successful in promoting health quality by preventing various infectious diseases and minimizing mortality and morbidity all over the world. However, the indiscriminate use of antibiotics has led to the emergence of multi-drug-resistant bacteria, which pose a serious threat to health care sector. Therefore, it is necessary to develop novel antimicrobial agents with versatile characteristics, such as antibacterial activity, low toxicity, wound healing potency, and antioxidant property.

Comment on "gemcitabine, PI3kinase-Akt pathway inhibition and radiation in human glioma cell lines" by M.S. Elnaggar et al..

The combination of gemcitabine, PI3K-Akt pathway inhibitors, and radiation in human glioma cell lines shows potential to enhance radiation sensitivity in aggressive brain tumors. Inhibiting the overactive PI3K-Akt pathway may increase tumor vulnerability to treatment. However, variability in responses among different glioma cell lines highlights the need for personalized approaches.