Incidence of postoperative pain after single-visit and multiple-visit root canal therapy: a systematic review.

AIM- The objective of the systematic review is to evaluate the incidence of postoperative pain after single-visit and multiple-visit root canal therapy. METHODS- Published research indexed in PubMed or Scopus or Cochrane or DOAJ or Web of Science evaluating the frequency percentage of postoperative aching after one and several root canal therapy appointments through randomized controlled trials or prospectively were included. RESULT- Most surveys utilized VAS (Visual Analogue Scale) to estimate the degree of pain among the participants.

Effectiveness of 'video-based interventions' of toothbrushing over other interventions on improvement of oral hygiene in children with Autism Spectrum Disorders (ASD): a systematic review and meta-analysis.

Background: Children with Autism exhibit impairment of fine motor co-ordination and sensory sensibilities and hence can directly affect the toothbrushing leading to poor oral hygiene.

Aim: This current systematic review and meta-analysis (SRMA) aims to evaluate the effectiveness of Video-based intervention of toothbrush training over other methods on improvement of oral hygiene in children with autism spectrum disorders (ASD) MATERIALS AND METHODS: Prospero no: (CRD42023450168). 'PubMed', 'Cochrane', 'Ovid' databases were searched from 1 January 1980 to 1 August 2023 using pre-defined search strategy.

A Carbazole Acrylonitrile Substituted Turn-On Fluorescence Chemosensors for Cyanide Ion and its Application to Real Sample Analysis.

An efficient probe (E)-2-(benzo[d]thiazol-2-yl)-3-(9-ethyl-9 H-carbazol-3-yl)acrylonitrile (CZ-BTZ) for selective fluorescence "turn-on" response with cyanide (CN) ion sensor was developed by simple Knoevenagel condensation of 9-ethyl-9 H carbazole-3-carbaldehyde with 2-(benzo[d]thiazol-2-yl) acetonitrile. The sensing ability of probe CZ-BTZ was tested with different inorganic anions through spectrophotometric and spectrofluorimetric methods. The UV-vis and fluorescence spectral studies show the formation of a new adduct between CZ-BTZ and CN by appearing with a new absorbance band at 350 nm and "turn-on" fluorescence at 535 nm in CHCN: HO (8:2, v/v, pH 7.

Global prevalence of pre eruptive intracoronal resorption (PEIR) of teeth: a systematic review of literature.

Aim: Pre-eruptive intracoronal resorption (PIER) defects constitute an important part of anomalies associated with unerupted teeth. However, these defects are usually overlooked by clinicians whilst interpreting radiographs. This systematic review was thus orchestrated to find the global prevalence of PEIR.

Targeting necroptosis in MCF-7 breast cancer cells: In Silico insights into 8,12-dimethoxysanguinarine from Eomecon Chionantha through molecular docking, dynamics, DFT, and MEP studies.

Breast cancer remains a significant challenge in oncology, highlighting the need for alternative therapeutic strategies that target necroptosis to overcome resistance to conventional therapies. Recent investigations into natural compounds have identified 8,12-dimethoxysanguinarine (SG-A) from Eomecon chionantha as a potential necroptosis inducer. This study presents the first computational exploration of SG-A interactions with key necroptotic proteins-RIPK1, RIPK3, and MLKL-through molecular docking, molecular dynamics (MD), density functional theory (DFT), and molecular electrostatic potential (MEP) analyses.

Practices and preferences in the use of magnification among endodontists and restorative dentists: A multicentre study.

Background And Objectives: Aim of the current study was to assess the perception, preference, and practice of endodontists and restorative dentists at different locations around the world about dental magnification instruments.

Materials And Methods: A multicenter, cross-sectional study was ethically approved from the local committee of bioethics. After thorough literature search, a questionnaire was designed and validated.

Investigation of electrochromic performances of multicolor VO devices fabricated at low processing temperature.

In recent decades, poorly insulated windows have increased the energy consumption of heating and cooling systems, thus contributing to excessive carbon dioxide emissions and other related pollution issues. From this perspective, the electrochromic (EC) windows could be a tangible solution as the indoor conditions are highly controllable by these smart devices even at a low applied voltage. Literally, vanadium pentoxide (VO) is a renowned candidate for the EC application due to its multicolor appearance and substantial lithium insertion capacity.

Efficacy of different adhesive systems in bonding direct resin composite restorations: a systematic review and meta-analysis.

Objective: This study aimed to identify and evaluate scholarly research on the efficacy, durability, and long-term stability of various adhesive systems used for bonding direct resin composite restorations and to identify factors influencing bonding performance, such as adhesive composition, application protocol, substrate type, and etching technique.

Materials And Methods: An all-inclusive electronic database search for peer-reviewed scholarly journal articles was conducted using PubMed, ScienceDirect, Google Scholar, Dimensions, and the Cochrane Library for research articles investigating the effectiveness of different adhesive systems in direct resin composite restorations, excluding reviews, meta-analyses, opinion pieces, and case reports. The risk of bias was assessed using the Cochrane tool (Robvis 2.

Computational study on water based hybrid photovoltaic systems with different absorber configurations.

The current study assesses several water-based PVT system thermal absorber configurations. The thermal absorber in PVT system plays a vital role in efficiency evaluation as it lowers PV temperature and collects heat energy. The current study aims to discover and analyze advanced thermal absorber design by comparing well-received spiral circular absorbers and non-cooled PV with proposed semi-circular thermal absorbers with varying flow configurations.

A rare case of pigmented seborrhoeic keratosis of scalp.

Seborrheic keratosis (SK) is a prevalent hyperkeratotic dermatological condition characterized by benign proliferation of epidermal keratinocytes, typically occurring in the middle to advanced stages of life. While the trunk is the primary site for lesions, they can also manifest on the extremities, face, and scalp. Although SK is typically benign, there can be morphological overlap with malignant skin lesions, necessitating meticulous differentiation for an accurate diagnosis.

Quorum quenching nanoparticles against wound pathogens - A scoping review.

Introduction: Quorum sensing (QS) enables bacteria to coordinate colony-wide activities, including those associated with infections. Quorum quenching (QQ) inhibits QS and is a promising method for controlling bacterial infections. Several In vitro experiments have been conducted to identify nanoparticles (NPs) as potential quorum quenching inhibitors.

Utilizing perfusion index for early identification of circulatory shock in neonates.

Introduction: Neonatal circulatory shock poses a significant challenge in intensive care settings and necessitates early recognition and intervention to prevent adverse outcomes. The perfusion index (PI), derived from pulse oximetry signals, is a potential adjunct tool for assessing peripheral perfusion and predicting shock in neonates. This prospective observational study aimed to evaluate the correlation between PI and circulatory shock in neonates with the goal of establishing PI as an objective parameter for early shock identification.

Etiological factors and management of vertigo - a retrospective study.

Introduction: Vertigo and dizziness are symptoms of various underlying conditions, ranging from benign to severe, affecting up to 40% of adults. Understanding the etiological factors and demographic characteristics associated with these symptoms is crucial for improving diagnostic accuracy and management. This study aims to identify the etiological factors contributing to vertigo and dizziness in a clinical setting and assess the effectiveness of treatment strategies.

An in vitro evaluation of anti-oxidant properties of novel nano-composite material containing titanium oxide, zinc oxide and green tea extract.

Introduction: Green tea is a medicinal beverage extracted from the plant Camellia sinensis. Antioxidants that exist naturally can be extracted as pure compounds from their parent materials for nutraceutical and medicinal applications. The present study aims to assess the antioxidant activity of Zinc oxide-titanium dioxide nano-composites (ZnO-TiO2 NCs) containing green tea extract.

In vitro evaluation of anti-inflammatory, anti-oxidant activity of pomegranate peel extract mediated calcium sulfate nano particles.

Introduction: Pomegranate peel is considered a reservoir of biologically active compounds, the presence of which provides anti-inflammatory and antioxidant properties to peel extracts. Calcium sulfate is considered an ideal boneaugmenting material, and in the present study, pomegranate peel extract-mediated calcium sulfate nano particles (PPE CaSo4 NPs) were synthesized and their anti-inflammatory and antioxidant properties were evaluated. This study aimed to evaluate the biological effects of PPE CaSo4 NPs, with a focus on their anti-inflammatory and antioxidant properties.

A randomized comparative study to prevent supine hypotension syndrome in pregnant females undergoing LSCS after giving spinal anesthesia using a wedge and novel 3D printed uterine displacement device.

Introduction: Pregnancy induces physiological changes, including alterations in cardiovascular dynamics, predisposing pregnant women to supine hypotension syndrome (SHS) during lower-segment cesarean section (LSCS) under spinal anesthesia. Various methods, including manual displacement of the uterus and use of wedges or cushions, have been proposed to prevent SHS, but their effectiveness remains variable. This study aimed to compare the efficacy of a novel 3D-printed uterine displacement device with that of a traditional wedge in preventing SHS during LSCS after spinal anesthesia.

Evaluation of antidiabetic and anti-inflammatory action of selenium nanoparticles mediated through aspalathus linearis - An in vitro study.

Introduction: Selenium nanoparticles (SeNPs) have drawn a lot of interest among researchers because of their distinct impact on antioxidant activity, anti-inflammatory tests, antibacterial activity, and in the treatment of various diseases. A. linearis has shown great findings in biomedical applications because of its physio-chemical compounds such as Aspalathin, orientin, and isoorientin.

Ocimum gratissimum mediated synthesis of AgNPs - An in vitro analysis of anti-inflammatory and antimicrobial effects.

Introduction: Silver nanoparticles (AgNPs) are effective against almost all kinds of pathogenic organisms. The green synthesis of AgNPs utilizing extracts from medicinal plants is being researched to examine the therapeutic advantages of AgNPs because the chemical production of AgNPs is more toxic. In this study, the stem extract of Ocimum Gratissimum (OG) also known as Karunthulasi or wild basil for green synthesis of AgNPs and evaluating their antiinflammatory and antimicrobial effects.

Impact of resistance training on cardiometabolic health-related indices in patients with type 2 diabetes and overweight/obesity: a systematic review and meta-analysis of randomised controlled trials.

Objective: To evaluate the effects of resistance training on cardiometabolic health-related outcomes in patients with type 2 diabetes mellitus (T2DM) and overweight/obesity.

Design: Systematic review and meta-analysis of randomised controlled trials (RCTs).

Data Sources: PubMed, Web of Science, Scopus, Science Direct, Cochrane Library and Google Scholar databases were searched from inception up to May 2024.

Correction: Kannampuzha et al. A Systematic Role of Metabolomics, Metabolic Pathways, and Chemical Metabolism in Lung Cancer. 2023, , 381.

Following the publication of paper [...

Evaluating the Binding Potential and Stability of Drug-like Compounds with the Monkeypox Virus VP39 Protein Using Molecular Dynamics Simulations and Free Energy Analysis.

Monkeypox is a re-emerging viral disease with features of infectiously transmitted zoonoses. It is now considered a public health priority because of its rising incidence and transmission from person to person. Monkeypox virus (MPXV) VP39 protein is identified as an essential protein for replication of the virus, and therefore, it is a potential target for antiviral drugs.

Exosomes derived from human adipose mesenchymal stem cells act as a therapeutic target for oral submucous fibrosis.

Oral submucosal fibrosis is a highly malignant oral condition that necessitates the use of sophisticated therapeutic procedures. OSF is a multifactorial precancerous condition induced by areca nut chewing, deficiencies in vitamins and trace minerals, immunological aspects, and hereditary factors. Adipose tissue-derived mesenchymal stem cells possess the capability for multidirectional activation and are extensively distributed throughout the body.

Exploration of magnetic zeolite thin film derived from coal fly ash an efficient sorbent: Application to water treatment.

Fly ash, produced during coal combustion for energy making, which is recognized as an industrial by-product, could lead to environmental health hazards. Subsequently, fly ash found that an exceptional adsorption performance for the removal of various toxic pollutants, the adsorption capacity of fly ash might be altered by introducing physical/chemical stimulation. Successfully converting fly ash into zeolites not only recovers their disposal difficulties but also transforms unwanted materials into merchandisable products for various industrial applications.