Molecular analysis of HPV16 and HPV18 oncogenes in oral squamous cell carcinoma: Structural, transcriptomic and insights.

The present study investigated the involvement of human papillomavirus (HPV)16 and HPV18 in oropharyngeal malignancies in order to understand the oncogenic mechanisms, and to identify biomarkers for early detection and treatment targets. Given the rising incidence of HPV-associated cancer, particularly in India, this holds significance in elucidating the molecular basis of these diseases. Structural validation of HPV16 and 18 oncoproteins E6 and E7 was conducted using computational tools, while gene expression profiles related to oral squamous cell carcinoma (OSCC) were analyzed to assess differential expression.

A Carbazole Acrylonitrile Substituted Turn-On Fluorescence Chemosensors for Cyanide Ion and its Application to Real Sample Analysis.

An efficient probe (E)-2-(benzo[d]thiazol-2-yl)-3-(9-ethyl-9 H-carbazol-3-yl)acrylonitrile (CZ-BTZ) for selective fluorescence "turn-on" response with cyanide (CN) ion sensor was developed by simple Knoevenagel condensation of 9-ethyl-9 H carbazole-3-carbaldehyde with 2-(benzo[d]thiazol-2-yl) acetonitrile. The sensing ability of probe CZ-BTZ was tested with different inorganic anions through spectrophotometric and spectrofluorimetric methods. The UV-vis and fluorescence spectral studies show the formation of a new adduct between CZ-BTZ and CN by appearing with a new absorbance band at 350 nm and "turn-on" fluorescence at 535 nm in CHCN: HO (8:2, v/v, pH 7.

Investigation of electrochromic performances of multicolor VO devices fabricated at low processing temperature.

In recent decades, poorly insulated windows have increased the energy consumption of heating and cooling systems, thus contributing to excessive carbon dioxide emissions and other related pollution issues. From this perspective, the electrochromic (EC) windows could be a tangible solution as the indoor conditions are highly controllable by these smart devices even at a low applied voltage. Literally, vanadium pentoxide (VO) is a renowned candidate for the EC application due to its multicolor appearance and substantial lithium insertion capacity.

Retraction notice to "Modified poly(vinylidene fluoride) nanomembranes for dye removal from water - A review" [Chemosphere 322 (2023) 138152].

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/policies/article-withdrawal).

Label-free electrochemical assessment of human serum and cancer cells to determine the folate receptor cancer biomarker.

The folate receptor (FR) is a well-known biomarker that is overexpressed in many cancer cells, making it a valuable target for cancer diagnostics and therapeutic strategies. However, identifying cancer biomarkers remains a challenge due to factors such as lengthy procedures, high costs, and low sensitivity. This study presents the development of a novel, cost-effective biosensor designed for the detection of FR.

Designing a Simple Quinoline-Based Chromo-Fluorogenic Receptor for Highly Specific Quantification of Copper (II) Ions: Environmental and Bioimaging Applications.

Many industries use copper metal ions (Cu ions), and their salts are utilized as supplemental materials in both agriculture and medicine. Identifying and monitoring these Cu ions in biological and environmental specimens is crucial due to their association with several health issues. In this investigation, we have designed a simple quinoline-based receptor (E)-3-(((2,4-di-tert-butyl-5-hydroxyphenyl)imino)methyl)-6-methoxyquinolin-2(1H)-one (QAP) containing imine functional groups to inspect its capability to identify metal ions in a semi-aqueous medium.

Evaluation of the Antibacterial and Antioxidant Properties of Chemical Constituents of the Roots of : An Integrated Approach of Experimental and Computational Study.

is a medicinal plant used for the treatment of malaria, toothache, and stomach problems. The root parts of the plant are also used for healing liver disorders. Silica gel chromatography separation of CHCl/MeOH (1:1) and MeOH extracts of roots of result in the isolation of three compounds, namely, bergenin (), -sitosterol (), and epigallocatechin 3-gallate (), reported herein for the first time from the plant.

Unravelling the interaction of ethyl cinnamate in 2-hydroxypropyl and methyl-β-cyclodextrin by spectroscopic and theoretical evaluation for enhanced antibacterial activities.

Essential oil components are the most common agents used to inhibit pathogens. Ethyl cinnamate (ECIN) is a hydrophobic essential oil component with well-known antibacterial properties but is poorly soluble in water, which limits its applications. In this study, inclusion complexes (ICs) were prepared by encapsulating ECIN in β-cyclodextrin (βCD), 2-hydroxypropyl-βCD, or methyl-βCD using an ultrasonication method to enhance water solubility and thermal and antibacterial properties.

Ethnopharmacological Perspective for Treatment of Epilepsy: An Updated Review.

Plants have been used as healing agents since humanity began. This review presents the plant profiles inhabiting the world regarding their traditional usage by various tribes/ethnic groups for the treatment of epilepsy. The bibliographic investigation was carried out by analyzing standard reference textbooks, Science Direct, Google Scholar, Scopus, Medline, Web of Science, and PubMed databases.

Green synthesized CaO decorated ternary CaO/g-CN/PVA nanocomposite modified glassy carbon electrode for enhanced electrochemical detection of caffeic acid.

A highly selective, sensitive caffeic acid (CA) detection based on calcium oxide nanoparticles (CaO NPs) derived from extract of Moringa oleifera leaves decorated graphitic carbon nitride covalently grafted poly vinyl alcohol (CaO/g-CN/PVA) nanocomposite modified glassy carbon electrode (GCE) was studied. A facile sonochemical method was adapted to synthesis nanomaterials and characterized by HR-TEM (High resolution transmission electron microscopy), FT-IR (Fourier transform infrared spectroscopy), XRD (X-ray diffraction), FE-SEM (Field emission scanning electron microscopy), EDX (Energy dispersive X-ray analysis), Mapping and BET (Brunauer-Emmett-Teller) analysis, and electrochemical techniques. The nanocomposite modified GCE exhibited an excellent catalytic performance to the oxidation of CA under optimized conditions owing to better electron transfer efficiency, conductivity and high surface area of the electrode material.

The pyogenic granuloma: localization, incidence, clinical features.

Background: A pyogenic granuloma (PG) represents a swiftly proliferating benign vascular tumor situated in the skin or subcutaneous tissue, commonly observed as a reactive lesion in the orofacial area. This research intended to scrutinize the clinicopathological characteristics of pyogenic granulomas in the oral and maxillofacial region.

Methods: Seventy two participants, comprising 24 men (33%) and 48 women (67%), underwent surgical ablation of pyogenic granuloma in oral and maxillofacial regions utilizing 940nm and 980nm diode lasers.

Enhanced Electrochemical Performance of Highly Porous CeO-Doped Zr Nanoparticles for Supercapacitor Applications.

The aim of this work was to develop an ultrasonic-assisted synthesis method for the fabrication of CeO-doped Zr nanoparticles that would improve the performance of supercapacitor electrodes. This method, which eliminates the need for high-temperature calcination, involves embedding CeO into Zr nanoparticles through 1 hr (CeO-Zr-1) and 2 hrs (CeO-Zr-2) of ultrasonic irradiation, resulting in the formation of nanostructures with significant improvements in their electrochemical properties. Through physicochemical analysis, we observed that the CeO-doped Zr nanoparticles, particularly those treated for 2 hrs (CeO-Zr-2), exhibit superior crystalline phase purity, optimal chemical surface composition, minimal agglomeration with particle sizes below 50 nm, and an impressive average surface area of 178 m/g.

Cost-Effective Synthesis of MXene Cadmium Sulfide (CdS) for Heavy Metal Removal.

Background Environmental contamination resulting from the release of untreated industrial wastewater has emerged as a critical worldwide issue. These effluents frequently have high levels of heavy metals and antibiotics, which are bad for aquatic ecosystems and human health. Oftentimes, conventional wastewater treatment techniques fall short of effectively eliminating these pollutants.

Development of a sustainable and disposable modified Bi-CdFeO electrode for electrochemical sensing of lead (II) and Acetaminophen drug molecule.

The study of research proposes a systematic pattern for optimization and fabrication of a sustainable-cost effective electrochemical sensor made by Bi-CdFeO (BCDF) nanoparticle and graphite powder. The structural examinations of synthesized BCDF materials were analyzed by specific spectral techniques viz.; P-XRD, SEM-EDX, TEM, XPS, FT-IR and DRS techniques.