Sensory Characteristics and Impact of Flavanol-Rich Grape and Blueberry Extract on Blood Flow Velocity and Oxidative Stress.

Background: Several epidemiological studies and intervention trials have demonstrated that grapes and blueberries, which are rich in flavanols, can lower the risk of cardiovascular disease. However, the mechanisms of action of these compounds remain unclear due to their low bioavailability.

Objective: This study aimed to characterize the sensory properties, blood flow velocity, and oxidative stress of a polyphenol rich grape and blueberry extract (PEGB) containing approximately 16% flavanols (11% monomers and 4% dimers).

Fluoroscopy-guided aspiration of the acutely dislocated total hip arthroplasty: a feasible, high-yield, and safe procedure.

Objective: To determine the feasibility, yield, and safety of fluoroscopic-guided aspiration of the acutely dislocated total hip arthroplasty (AD-THA).

Materials And Methods: IRB-approved, retrospective review of fluoroscopic-guided aspirations of AD-THA (January 2005-December 2023) was performed. Data from electronic charts and fluoroscopy images/reports were obtained.

Analytical review of facial nerve palsy following SARS-CoV-2 vaccination: comprehensive assessment.

Purpose: The SARS-CoV-2 vaccination has reduced COVID-19 infection, though facial nerve palsy (FNP) has emerged as a notable side effect of the vaccine. We evaluated the current literature on the clinical presentation and outcomes of FNP related to COVID-19 vaccination.

Methods: A comprehensive search of seven databases was conducted for studies up to January 2023.

Resveratrol mitigates heat stress-induced testicular injury in rats: enhancing male fertility via antioxidant, antiapoptotic, pro-proliferative, and anti-inflammatory mechanisms.

This study investigates the protective effects of resveratrol (RSV) against heat stress (HS)-induced testicular injury in rats. Climate change has exacerbated heat stress, particularly affecting male fertility by impairing testicular function and sexual behavior. A total of 32 rats were allocated into four experimental groups: control, RSV control, HS control, and RSV + HS.

Unraveling Antimicrobial Resistance Dynamics in Mycoplasma gallisepticum: Insights Into Antibiotic and Disinfectant Interactions.

A major risk to the poultry industry is antimicrobial resistance (AMR), specifically with regard to Mycoplasma gallisepticum (MG) infections. The sensitivity patterns of 100 MG isolates to biocides and antibiotics were examined in this study to clarify the interactions between antimicrobial agents and resistance mechanisms. The antimicrobial activity against MG was assessed using broth microdilution, and the results are shown as the minimum inhibitory concentration (MIC) for each strain, the MIC distribution (range), the MIC, and/or the MIC.

Clinical and Electromyographic Characteristics of Pediatric Laryngeal Dyskinesia.

Objective: To report the clinical and laryngeal electromyographic (LEMG) parameters of children with laryngeal dyskinesia (LD) and its prevalence among laryngeal mobility disorder (LMD) requiring full airway examination.

Study Design: Retrospective uncontrolled study.

Setting: Tertiary pediatric center.

Uncovering Antiviral Potential of Cistus ladanifer Extracts Against HSV-1 and SARS-CoV-2 by In Vitro and In Silico Analysis.

Infectious diseases remain a major global health concern. Cistus ladanifer, a plant commonly employed in Moroccan traditional medicine, has been identified as a potential antiviral candidate. This study aimed to evaluate the antiviral activity of C.

Current and future burden of female breast cancer in the Middle East and North Africa region using estimates from GLOBOCAN 2022.

Breast cancer is the most diagnosed female cancer and the most common cause of cancer death in women in the Middle East and North Africa (MENA) region. In this study, we aimed to describe the current patterns of breast cancer among women in the MENA region and estimate the burden for the year 2050. We used the estimates of the breast cancer incidence and mortality from the GLOBOCAN 2022 database and predicted the burden of breast cancer in 2050 according to different scenarios.

Complete genome sequence of B273 and its epidermicin NI01 biosynthesis plasmid.

The human skin commensal produces diverse, therapeutically relevant bacteriocins. We report the complete whole-genome sequence of the nasal isolate B273, which contains a plasmid with the biosynthetic gene cluster for epidermicin NI01, a broad-spectrum type II antimicrobial peptide.

An Assessment of the Cyto-Genotoxicity Effects of Green-Synthesized Silver Nanoparticles and ATCBRA Insecticide on the Root System of .

We aimed to synthesize silver nanoparticles (AgNPs) using (cardamom) extracts and assess the cytotoxicity and genotoxicity of the cardamom extract, -AgNPs, and the insecticide ATCBRA-commonly used for pest control-on the root system of (broad bean). The chemical composition of the aqueous cardamom extract was identified and quantified using GC-MS, revealing a variety of bioactive compounds also present in cardamom essential oil. These included α-terpinyl acetate (21.

The Role of Eustachian Tube Dysfunction in Recurrent Chronic Otitis Media: A Cross-Sectional Study of Anatomical and Functional Variations.

: Recurrent chronic otitis media (rCOM) is a major cause of hearing impairment, often linked to Eustachian tube (ET) dysfunction. Anatomical abnormalities, such as ET narrowing and obstructions, and functional impairments, including poor pressure regulation, play significant roles in rCOM recurrence. This study aimed to (1) identify anatomical variations of the ET in patients with rCOM using high-resolution imaging; (2) evaluate ET functional status using tympanometry, tubomanometry, and ET function tests; and (3) assess the correlation between anatomical variations and functional impairments in predicting rCOM recurrence.

Exploring Patient Activation and Compliance in Patients with Different Rheumatological Disorders.

This study aimed to assess patient activation using patient activation measure 13 (PAM-13) in systemic lupus erythematosus (SLE), psoriatic arthritis (PsA), and axial spondyloarthritis (axSPA). A cross-sectional study was conducted involving patients with three rheumatological conditions (SLE, PsA, and axSPA). Patients were contacted either at the clinic or through social media platforms.

Perceived Telehealth Usability for Personalized Healthcare Among the Adult Population in Saudi Arabia: A Cross-Sectional Study in the Post-COVID-19 Era.

: Due to technological advancements, the demand for easily accessible and convenient healthcare services is rising globally. Thus, telehealth is gaining momentum that was previously unheard of. The Kingdom of Saudi Arabia (KSA) actively embraces digital innovation in the healthcare industry through its ambitious Vision 2030 initiative.

Impact of the Cooperative Health Insurance System in Saudi Arabia on Universal Health Coverage-A Systematic Literature Review.

Background: This systematic review assesses the role of the Cooperative Health Insurance System (CHIS) in achieving Universal Health Coverage (UHC) in Saudi Arabia's evolving healthcare system by consolidating and analyzing findings from diverse studies to provide a comprehensive overview of CHIS's impact and also identifies contextual challenges and practical insights that can inform similar reforms globally.

Methods: We report results following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The following six databases were searched for relevant studies: PubMed, Scopus, CINAHL, Business Source Complete, APA PsycINFO, and SocIndex.

Machine Learning Algorithm-Based Prediction of Diabetes Among Female Population Using PIMA Dataset.

: Diabetes is a metabolic disorder characterized by increased blood sugar levels. Early detection of diabetes could help individuals to manage and delay the progression of this disorder effectively. Machine learning (ML) methods are important in forecasting the progression and diagnosis of different medical problems with better accuracy.

The Relationship Between Early Maladaptive Schemas and Intimate Partner Violence Against Women: The Moderating Effect of Childhood Trauma.

The study objectives were to test the hypothesis that childhood trauma moderates the associations between early maladaptive schemas (EMS) and intimate partner violence (IPV) among women in the specific Lebanese patriarchal context. This is a cross-sectional study that was conducted on Lebanese women between September and December 2018; 1,655 participants enrolled in this study were from all of Lebanon's governorates and were selected using an equitable representative sample. The "Disconnection and Rejection" EMS domain showed the strongest correlations with both physical and nonphysical IPV ( = .

Interchangeability of Contemporary Semi-adjustable Articulators Used Over Time: An Study.

Aim: The purpose of this study is to investigate the interchangeability of newly acquired, short-term used, and long-term used semi-adjustable articulators.

Materials And Methods: Metal analogs of partially dentate maxillary and mandibular arches were mounted on twelve semi-adjustable Stratos 300 articulators, divided into three groups based on usage over time: New, short-term used (<2 years), long-term used (>2 years) articulators. Each articulator was calibrated according to manufacturer guidelines, ensuring consistency.

A Comparative Analysis of Introvert and Extrovert Dental Students toward Clinical Performance.

Aim: This study aims to identify introvert and extrovert personality types among level-6 dental students in the College of Dentistry, Jazan University, Jazan, Saudi Arabia, and analyze their clinical performance.

Materials And Methods: In this causal-comparative research, 72 level-6 dental students (29 males and 43 females) of the College of Dentistry of Jazan University for the school year 2023-2024 were chosen to be the respondents. Myers-Briggs type indicator (MBTI), a personality test designed to differentiate introversion and extroversion, was used.

Country-specific key lifestyle factors and health outcomes for resource allocation in the general population: a network analysis across 29 countries.

Background: We aimed to identify the central lifestyle, the most impactful among lifestyle factor clusters; the central health outcome, the most impactful among health outcome clusters; and the bridge lifestyle, the most strongly connected to health outcome clusters, across 29 countries to optimise resource allocation for local holistic health improvements.

Methods: From July 2020 to August 2021, we surveyed 16 461 adults across 29 countries who self-reported changes in 18 lifestyle factors and 13 health outcomes due to the pandemic. Three networks were generated by network analysis for each country: lifestyle, health outcome, and bridge networks.

Public Awareness and Perception of Risks Associated With Neck Manipulations in Southern Saudi Arabia.

Introduction Neck manipulations, including massages and self-cracking, are common practices, yet public awareness of their potential risks is poorly understood. This study explores public knowledge and awareness of the risks associated with neck manipulations in the Southern region of Saudi Arabia. Methods The study employed a descriptive cross-sectional design from May 2024 to July 2024, distributing a questionnaire to the adult population in the Southern Region.

Protecting Future Generations From Hereditary Genetic Disorders Using Preimplantation Genetic Diagnosis: A Narrative Review Article.

Preimplantation genetic diagnosis (PGD) is provided by majority of reproductive clinics in the United States (US), and PGD is used in many in vitro fertilization (IVF) procedures every year. PGD is extensively used to screen for certain genetic abnormalities and aneuploidy in individuals undergoing IVF. Genetic disorders are very prevalent in Saudi Arabia.

Basic Life Support (BLS) Knowledge Among the Ha'il Region Population, Saudi Arabia: A Cross-Sectional Study.

Aims and background This study aims to evaluate Basic Life Support (BLS) knowledge among residents of the Ha'il region. It will reveal the public's familiarity with BLS and identify sources of BLS knowledge. The findings can guide policymakers in improving BLS training, potentially saving lives, especially during cardiac emergencies.

Popularity and Perceptions of Protein Supplementation: A Cross-Sectional Study Among Undergraduate University Students Aged 18 to 25 Years in Riyadh, Saudi Arabia.

Background And Aim:  Young adults, particularly those aged 18-25, exhibit varying perceptions and choices regarding the use of protein supplements (PS). Understanding these perceptions can significantly enhance professional guidance and nutrition education for undergraduate students. This study, conducted in Riyadh, Saudi Arabia, aims to explore the perceptions of PS use and identify the most popular PS among university students.

Retraction: Design and development of highly sensitive PEDOT-PSS/AuNP hybrid nanocomposite-based sensor towards room temperature detection of greenhouse methane gas at ppb level.

[This retracts the article DOI: 10.1039/D1RA00994J.].

Case report: Kabuki syndrome and persistent hypoglycemia in neonates.

The Kabuki syndrome (KS) is a rare congenital disease that has two different types, KS1 and KS2, with variant in epigenetic gene KMT2D and KDM6A, respectively. It is associated with multiple abnormalities such as (developmental delay, atypical facial features, cardiac anomalies, minor skeleton anomalies, genitourinary anomalies, and mild to moderate intellectual disability). This syndrome can lead to neonatal hypoglycemia that results from hyperinsulinemia and electrolyte abnormalities.