The clinical assessment of lung involvement in patients with Still's disease, results from the multicentre international AIDA Network Still's Disease Registry.

Objectives: To assess the lung involvement in patients with Still's disease, an inflammatory disease assessing both children and adults. To exploit possible associated factors for parenchymal lung involvement in these patients.

Methods: A multicentre observational study was arranged assessing consecutive patients with Still's disease characterized by the lung involvement among those included in the AIDA (AutoInflammatory Disease Alliance) Network Still's Disease Registry.

Factors Influencing Nursing Interns' Engagement in Fall Prevention Activities in Saudi Arabia.

Aim: To assess the knowledge, attitudes and engagement of nursing interns regarding fall prevention activities during their internship within hospital settings.

Design: This study used a cross-sectional design.

Methods: This was a cross-sectional, descriptive, correlational study.

Exploring the Anti-Adherence Potential of Skt35 to Combat Catheter-Associated Staphylococcus aureus Infections: Efficacy, Toxicity and Mechanism of Action.

Catheter-associated urinary tract infections (CAUTIs), often caused by biofilm-forming Staphylococcus aureus, present significant clinical challenges. Skt35, a dioxopiperidinamide derivative of cinnamic acid, was investigated for its potential antibacterial and antibiofilm activities against S. aureus biofilms.

Knowledge and attitude towards Herpes Simplex Virus-2 in Al-Jouf region, Saudi Arabia.

Introduction: Herpes simplex virus type-2 (HSV-2) infection is a sexually transmitted disease (STD) that causes genital ulcers. The prevalence of HSV-2 increases because of its asymptomatic shedding. This study aimed to evaluate community knowledge and attitude toward HSV-2 infection in Al-Jouf region.

Molecular cloning, sequencing, expression and purification of Alkhumra hemorrhagic fever virus capsid protein in Saudi Arabia.

Introduction: Alkhumra hemorrhagic fever virus (AHFV) is a newly discovered virus in the Flaviviridae family. It was discovered in 1995 among animal handlers in Saudi Arabia. AHFV spreads through close contact with infected animals and tick bites.

Epigallocatechin 3-gallate-induced neuroprotection in neurodegenerative diseases: molecular mechanisms and clinical insights.

Neurodegenerative diseases (NDs) are caused by progressive neuronal death and cognitive decline. Epigallocatechin 3-gallate (EGCG) is a polyphenolic molecule in green tea as a neuroprotective agent. This review evaluates the therapeutic effects of EGCG and explores the molecular mechanisms that show its neuroprotective properties.

Predicting few disinfection byproducts in the water distribution systems using machine learning models.

Concerns regarding disinfection byproducts (DBPs) in drinking water persist, with measurements in water treatment plants (WTPs) being relatively easier than those in water distribution systems (WDSs) due to accessibility challenges, especially during adverse weather conditions. Machine learning (ML) models offer improved predictions of DBPs in WDSs. This study developed multiple ML models to predict Trihalomethanes (THMs), Haloacetic Acids (HAAs), Dichloroacetonitrile (DCAN), and N-nitrosodimethylamine (NDMA) in WDSs using data collected over 13 years (2008-2020) from 113 water supply systems (WSS) in Ontario.

The interplay of senescence and MMPs in myocardial infarction: implications for cardiac aging and therapeutics.

Aging is associated with a marked increase in cardiovascular diseases, such as myocardial infarction (MI). Cellular senescence is also a crucial factor in the development of age-related MI. Matrix metalloproteinases (MMPs) interaction with cellular senescence is a critical determinant of MI development and outcomes, most notably in the aged heart.

Targeting senescence and GATA4 in age-related cardiovascular disease: a comprehensive approach.

The growing prevalence of age-related cardiovascular diseases (CVDs) poses significant health challenges, necessitating the formulation of novel treatment approaches. GATA4, a vital transcription factor identified for modulating cardiovascular biology and cellular senescence, is recognized for its critical involvement in CVD pathogenesis. This review collected relevant studies from PubMed, Google Scholar, and Science Direct using search terms like 'GATA4,' 'cellular senescence,' 'coronary artery diseases,' 'hypertension,' 'heart failure,' 'arrhythmias,' 'congenital heart diseases,' 'cardiomyopathy,' and 'cardiovascular disease.

Which is easier for beginners: supine or prone position percutaneous nephrolithotomy? Assessment of the learning curve in novice urologists through a randomized clinical trial.

Background: Percutaneous nephrolithotomy (PCNL) could be performed in both prone and supine positions. Each position has its own advantages and disadvantages. "Learning curve" is a graph that represents progress of a skill against the time needed to master the technique.

Atmospheric pressure spatial atomic layer deposition of p-type CuO thin films from copper(II) acetylacetonate and ozone for UV detection.

Cupric oxide (CuO) is a promising p-type semiconducting oxide used in many critical fields, such as energy conversion and storage, and gas sensors, which is attributed to its unique optoelectrical properties and cost-effectiveness. This work successfully deposited amorphous, pinhole-free, ultrathin CuO films using atmospheric pressure spatial atomic layer deposition (SALD) with copper(II) acetylacetonate and ozone as precursors. The growth rate increased from 0.

Impact of water stress to plant epigenetic mechanisms in stress and adaptation.

Water is the basic molecule in living beings, and it has a major impact on vital processes. Plants are sessile organisms with a sophisticated regulatory network that regulates how resources are distributed between developmental and adaptation processes. Drought-stressed plants can change their survival strategies to adapt to this unfavorable situation.

Antiangiogenic potential of extracts and molecular docking study by targeting VEGFR-2 pathway.

Background: Anti-angiogenesis or inhibition of blood vessel formation is the best way to prevent the growth and metastasis of tumors. Natural sources like plants are currently being explored for its antiangiogenic activity as they are factories of various phytochemicals. The goal of the current study is to investigate the antiangiogenic potential of () by using chorioallantoic membrane (CAM) assay and molecular docking.

Wheel-shaped polyoxometalates as nanozymes for autophagy-augmented and phototherapy-involved cancer nanotherapy.

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Green synthesis of Ag-Fe bimetallic nanoparticles using fungal filtrates: unlocking multifunctional medical and environmental applications.

The current investigation focuses on synthesizing Ag-Fe bimetallic nanoparticles (AgFe-BMNPs) using cell-free filtrates of the as a novel fungal reducing agent. The optical, morphological, and surface properties of these fungus-fabricated AgFe-BMNPs and their monometallic counterparts (AgNPs and FeNPs) were analyzed using sophisticated nanotechnology instruments. The UV-visible spectrum showed peaks at 231 nm and 415 nm for BMNPs and 450 nm and 386 nm for AgNPs and FeNPs, respectively.

Schiff bases targeting an Sw-480 colorectal cell line: synthesis, characterization, ds-DNA binding and anticancer studies.

In present studies, six Schiff bases were prepared, characterized and evaluated for their anti-tumor activity against the colorectal cancer cell line SW-480. The test compounds were characterized by various physico-chemical techniques such as M. P.

Acaricidal and insecticidal activities of entomopathogenic nematodes combined with rosemary essential oil and bacterium-synthesized silver nanoparticles against camel tick, and wax moth, .

An innovative approach to ticks and insect pests management is necessary to mitigate the challenges posed by the indiscriminate use of chemical pesticides, which can lead to resistance development and environmental pollution. Despite their great potential, biological control agents have significant manufacturing, application, and stability limitations. Currently, using phytochemicals, biosynthesized nanoparticles, and bioagents to get rid of arthropods might be a good alternative that would make farmers less worried about residues and resistance.

Enhancing soybean germination and vigor under water stress: the efficacy of bio-priming with sodium carboxymethyl cellulose and gum arabic.

Seed priming can significantly enhance the tolerance of soybean against different environmental stresses by improving seed water uptake and modulating stress-response mechanisms. In particular, seed priming with sodium carboxymethylcellulose (SCMC) and gum Arabic (GA) can support seeds to withstand extreme conditions better, promoting more consistent germination and robust seedling establishment, which is crucial for achieving stable agricultural yields. The present study investigated the effects of seed priming using a combination of SCMC and GA (10% CG) on the germination, growth, and biochemical responses of six soybean varieties under drought and flooding stress conditions.

A concept analysis of vicarious resilience in mental health nursing.

Objective: The introduction of the vicarious resilience concept in psychology and mental health nursing literature is a highly promising advancement. By utilizing this novel concept, experts in various domains can enhance their comprehension of how to foster resilience in individuals by observing and learning from the resilience of others. This concept analysis aims to elucidate the concept of vicarious resilience in mental health nursing by defining its related attributes, antecedents, and consequences.

Antioxidative and Anticancer Potential of Luteolin: A Comprehensive Approach Against Wide Range of Human Malignancies.

Luteolin is widely distributed phytochemical, a flavonoid, in kingdom plantae. Luteolin with potential antioxidant activity prevent ROS-induced damages and reduce oxidative stress which is mainly responsible in pathogenesis of many diseases. Several chemo preventive activities and therapeutic benefits are associated with luteolin.

Investigating the link between microplastic exposure (benzyl butyl phthalate) and neurodegenerative diseases using high-performance computational toxicology.

Background: Microplastics are tiny plastic particles, typically less than 5 mm in size, formed from the breakdown of larger plastic products. This breakdown releases additives, including benzyl butyl phthalate (BBP), into the environment. Humans can be exposed to BBP through contaminated food and water, inhalation, and dermal contact.

The psychological resources of success: satisfaction with academic majors, psychological capital, and achievement motivation among future tourism and hospitality leaders.

Introduction: Exploring the factors that drive academic achievement motivation is a vital area in educational psychology, particularly within specialized fields like tourism and hospitality higher education. Achievement motivation, essential for academic and career success, is shaped by various positive psychological resources and contextual factors. Grounded in the framework of positive psychology, this study examines how satisfaction with academic majors (SAT) predicts achievement motivation among tourism and hospitality students in Saudi Arabia.

The Impact of Idiopathic Intracranial Hypertension on Cardiovascular Disease Risk Among UK Women: An Obesity-Adjusted Analysis.

Introduction: Idiopathic intracranial hypertension (IIH) is known to elevate cardiovascular disease (CVD) risk, but the extent to which obesity and IIH-specific factors contribute to this risk is not well understood. WE aim to separate the effects of obesity from IIH-specific factors on the risk of stroke and CVD, building on previous findings that indicate a two-fold increase in cardiovascular events in women with IIH compared to BMI-matched controls.

Methods: An obesity-adjusted risk analysis was conducted using Indirect Standardization based on data from a cohort study by Adderley et al.

Effect of relaxing sounds on anxiety levels in patients undergoing dental extraction: A randomized clinical trial.

Introduction: The study was conducted to observe the effect of using relaxing sounds as a nonpharmacological intervention on anxiety levels and vital signs among patients who underwent extraction.

Materials And Methods: A randomized clinical trial was conducted, and patients with an indication of dental extraction, who were physically and mentally healthy, were invited to voluntarily participate in the study. Dental anxiety was assessed by measuring blood pressure, heart rates, and respiratory rates as well as with the help of the Modified Dental Anxiety Scale (MDAS) questionnaire before and after the procedure.

Association of self-reported bruxism and academic performance in Jazan University dental students: A cross-sectional study.

Aims: The purpose of this cross-sectional descriptive study was to investigate the association between self-reported bruxism and academic performance among dental students at Jazan University.

Material And Methods: One hundred sixty-eight students (73 males and 95 females) were evaluated in this study, between the age groups of 18 years and above. Self-reported bruxism was measured by utilizing a customized questionnaire.