Comparative analysis of brushless DC and switched reluctance motors for optimizing off-grid water pumping.

Off-grid water pumping systems (OGWPS) have become an increasingly popular area of research in the search for sustainable energy solutions. This paper presents a finite element method (FEM)-based design and analysis of Brushless-DC (BLDC) and Switched Reluctance Motors (SRM) designed for low-power water pumping applications. Utilizing adaptive finite element analysis (FEA), both motors were designed with identical ratings and design parameters to ensure a fair comparison.

An optimal workflow scheduling in IoT-fog-cloud system for minimizing time and energy.

Today, with the increasing use of the Internet of Things (IoT) in the world, various workflows that need to be stored and processed on the computing platforms. But this issue, causes an increase in costs for computing resources providers, and as a result, system Energy Consumption (EC) is also reduced. Therefore, this paper examines the workflow scheduling problem of IoT devices in the fog-cloud environment, where reducing the EC of the computing system and reducing the MakeSpan Time (MST) of workflows as main objectives, under the constraints of priority, deadline and reliability.

Synergistic effect of Canarium strictum leaves extract and KI on the corrosion protection of mild steel in 15% HCl solution.

The inhibitory potential of an alcoholic extract derived from Canarium strictum leaves (CSL) was evaluated as a corrosion inhibitor for mild steel (MS) in 15% HCl solution. Furthermore, to enhance its inhibition effectiveness, the influence of potassium iodide (KI) was also examined. The corrosion inhibition and adsorption characteristics of CSL were comprehensively analysed through weight loss measurement, electrochemical impedance measurement (EIS), potentiodynamic polarization (PP), UV-visible spectroscopy, Fourier transform infrared spectroscopy (FTIR), atomic force microscopy (AFM), scanning electron microscopy and energy dispersive spectroscopy (SEM-EDS).

Soliton solutions of the (2 + 1)-dimensional Jaulent-Miodek evolution equation via effective analytical techniques.

In this study, we investigate the [Formula: see text]-D Jaulent-Miodek (JM) equation, which is significant due to its energy-based Schrödinger potential and applications in fields such as optics, soliton theory, signal processing, geophysics, fluid dynamics, and plasma physics. Given its broad utility, a rigorous mathematical analysis of the JM equation is essential. The primary objective of this work is to derive exact soliton solutions using the Modified Sub-Equation (MSE) and Modified Auxiliary Equation (MAE) techniques.

Impact of Dandelion (Taraxacum officinale) leaf aqueous extract on immunological response of mice after Schistosoma mansoni infection.

This study investigated the effect of dandelion (Taraxacum officinale) leaf aqueous extract (DLE) on the immunological response of mice following infection with Schistosoma mansoni. Mice (in groups of 7) were first experimentally infected with S. mansoni and, 6 weeks later, were treated with praziquantel (PZQ) and/or DLE.

Computational identification and experimental validation of novel microRNAs along with their targets through RT-PCR approach.

Various metabolic and cell signaling processes impact the functions of sugarcane plant cells. MicroRNAs (miRNAs) play critical regulatory roles in enhancing yield and providing protection against various stressors. This study seeks to identify and partially characterize several novel miRNAs in sugarcane using tools, while also offering a preliminary assessment of their functions.

A Monte Carlo simulation and meta-analysis of health risk due to formaldehyde exposure at different seasons of the year in various indoor environments.

Formaldehyde is considered as a significant contaminant. This study aimed to perform comprehensive research with systematic review, health risk estimation, meta-analysis, and Monte Carlo simulation to evaluate exposure to formaldehyde at different seasons of the year in various indoor environments. A systematic literature review was initially performed.

Tracing microplastics in environmental sources and migratory shorebirds along the Central Asian Flyway.

Microplastic pollution poses a significant threat to coastal ecosystems worldwide. Despite its widespread occurrence, knowledge on the prevalence and fate of microplastics across food webs is limited. To bridge this gap, we conducted an extensive study on microplastic contamination in mudflats, mangroves, and sand beaches being key habitats for wintering shorebirds on the west coast of India.

Mitigative effects of didymin against cadmium-induced renal injury via regulating Nrf-2/Keap-1, apoptosis, inflammation and oxidative stress.

Background: Cadmium (Cd) is a toxic heavy metal present in environment that has potential to instigate renal toxicity. Didymin (DDM) is a natural flavone, which shows anti-oxidant, anti-inflammatory and antiapoptotic nature. Therefore, the current study was formulated to appraise attenuative potential of DDM against Cd instigated nephrotoxicity.

Nutritional interventions in depression: The role of vitamin D and omega-3 fatty acids in neuropsychiatric health.

Background: Depression is a pervasive mental health disorder with complex etiologies involving neurotransmitter imbalances, inflammation, and hormonal dysregulation. Emerging evidence highlights the significance of nutritional interventions in improving depressive symptoms.

Objective: This review explores the mechanisms of action and clinical applications of Vitamin D and Omega-3 fatty acids in managing depression, providing insights into their potential therapeutic roles.

Photic drive response in people with epilepsy: Exploring the interaction with background alpha rhythm.

Photic drive responses (PDRs) are used to explore cortical hyperexcitability. We quantified PDRs and interactions with the alpha rhythm in people with epilepsy (PwE). Fifteen PwE (mean age ± SD 47.

Fipronil in sub-lethal doses leads to immuno-toxicological effects in broiler birds.

Pesticides, including fipronil, are used mainly in agriculture; however, in veterinary and animal husbandry, their potential use is to control the pests responsible for vector-borne diseases. Their residues in agriculture products and direct use on farms are responsible for potentially harming livestock and poultry. So, this study was designed to evaluate the toxico-pathological effects of fipronil on the immune system of poultry birds.

Use of evidence-based health professions education: Attitudes and practices of academic leaders.

Purpose: The objective of this study was to explore the attitudes, practices, supports, and barriers of academic leaders regarding the use of Evidence-Based Health Professional Education (EBHPE).

Methods: A cross-sectional survey was conducted on 79 faculty members in leadership positions, from four different undergraduate colleges at Qassim University. A pre-validated questionnaire was distributed electronically.

Investigating Pb2 CAP-binding domain inhibitors from marine bacteria for targeting the influenza A H5N1.

The ongoing increase in the prevalence and mutation rate of the influenza virus remains a critical global health issue. A promising strategy for antiviral drug development involves targeting the RNA-dependent RNA polymerase, specifically the PB2-cap binding domain of Influenza A H5N1. This study employs an in-silico approach to inhibit this domain, crucial for viral replication, using potential inhibitors derived from marine bacterial compounds.

A Comprehensive Evaluation of the Neuropharmacological Potential of Methanolic Leaf Extract of Acanthus ebracteatus (Vahl.) Using Experimental and In Silico Approaches.

This study was undertaken to assess the antioxidant and neuropharmacological potentials of the methanol leaf extract of Acanthus ebracteatus (MAEL) through experimental and in silico methods. The phytochemical screening (PS) and GC-MS (gas chromatography-mass spectrometry) identified 28 phytochemicals with different classes in nature in MAEL. The MAEL revealed better antioxidant activity through various in vitro antioxidant assays.

Description of six novel species sp. nov., sp. nov., sp. nov., sp. nov., sp. nov. and sp. nov., isolated from mangrove ecosystem.

Six Gram-stain-positive and rod-shaped strains, designated FJAT-51614, FJAT-51639, FJAT-52054, FJAT-52991, FJAT-53654 and FJAT-53711, were isolated from a mangrove ecosystem. The condition for growth among the strains varied (pH ranging 5.0-11.

Screening of Oncogenic Proteins and Development of a Multiepitope Peptide Vaccine Targeting AKT1 and PARP1 for Breast Cancer by Integrating Reverse Vaccinology and Immune-Informatics Approaches.

Background: Breast cancer remains a significant global health challenge, requiring innovative therapeutic strategies. In silico methods, which leverage computational tools, offer a promising pathway for vaccine development. These methods facilitate antigen identification, epitope prediction, immune response modelling, and vaccine optimization, accelerating the design process.

Seroprevalence and Risk Factors of Anaplasma marginale in Water Buffaloes in Nile Delta of Egypt.

Purpose: Bovine anaplasmosis is a major tick-borne disease in ruminants, resulting in significant economic loss for the dairy sector. This study aimed to evaluate the seroprevalence of Anaplasma marginale (A. marginale) in buffaloes in three governorates in Nile Delta of Egypt.

Quinoline and quinolone carboxamides: A review of anticancer activity with detailed structure-activity relationship analysis.

Quinoline is a highly privileged scaffold with significant pharmacological potential. Introducing a carbonyl group into the quinoline ring generates a quinolone ring, which exhibits promising biological properties. Incorporating a carboxamide linkage at different positions within the quinoline and quinolone frameworks has proven an effective strategy for enhancing pharmacological properties, particularly anticancer potency.

Bioinformatics and immunoinformatics approaches in the design of a multi-epitope vaccine targeting CTLA-4 for melanoma treatment.

Melanoma, a highly aggressive skin cancer, remains a significant cause of mortality despite advancements in therapeutic strategies. There is an urgent demand for developing vaccines that can elicit strong and comprehensive immune responses against this malignancy. Achieving this goal is crucial to enhance the efficacy of immunological defense mechanisms in combating this disease.

Evaluating the efficacy of nano-cyclosporine A in mice model of ulcerative colitis: a meta-analysis.

Cyclosporine A is an immunosuppressive drug used in clinics to treat steroid-refractory ulcerative colitis (UC). However, due to its side effects, researchers are evaluating novel drug delivery-based treatment options. Nanoparticles-based cyclosporine (Nano-CSA) offers a promising option for the treatment of UC, and various in vivo studies on animals have been conducted.

Effect of Vitamin D Supplementation on Lipid Profile in Overweight or Obese Women: A Meta-analysis and Systematic Review of Randomized Controlled Trials.

Context: Previous studies have explored the relationship between vitamin D and lipid profile in individuals with obesity or overweight women, but the results have been inconsistent.

Objective: This meta-analysis and systematic review of randomized controlled trials (RCTs) was conducted to assess the effect of vitamin D on lipid profile in women who are overweight or obese.

Data Sources: A meticulous search strategy was used across the Scopus, PubMed/Medline, Web of Science, and Embase databases up to June 2024.

Positive feedback regulation between RpoS and BosR in the Lyme disease pathogen.

In , the causative agent of Lyme disease, differential gene expression is primarily governed by the alternative sigma factor RpoS (σ). Understanding the regulation of RpoS is crucial for elucidating how is maintained throughout its enzootic cycle. Our recent studies have shown that the homolog of Fur/PerR repressor/activator BosR functions as an RNA-binding protein that controls the mRNA stability.