A quantitative and qualitative comparative analysis of collagen fibers to determine the role of connective tissue stroma in oral squamous cell carcinoma using special stains and polarized microscopy.

Background: Solid tumors such as oral squamous cell carcinoma (OSCC) are composed of malignant epithelial cells and the stroma in which these cells are dispersed. As the tumor progresses, the extracellular matrix undergoes dramatic morphological and architectural changes. Special stains make analysis easy and less erroneous by highlighting the area of interest and can be used to study these changes.

Comparison of Antimicrobial Efficacy of Four Different Plant Extracts against Cariogenic Bacteria: An Study.

Background: Dental caries is an oral disease which is infectious in nature associated with various pathogenic microorganisms and is prevalent across the world.

Aim: To evaluate and compare the anticariogenic properties of the different plant extracts against various cariogenic microorganisms.

Materials And Methods: In phase I, the anticariogenic efficacy of four different herbal extracts, namely (), (), (), and (Licorice), was evaluated against two strains of bacteria viz.

Teleassistance and teleconsultation using smartphones and its contribution in clinical progress of oral and maxillofacial surgery.

Smartphones, an advanced mobile device having combined function of a computer and cellular phone, have become an effective communication within and between specialties for management of patients. It provides voice, text, multimedia messages, camera, and E-mail option and helps the surgical team to communicate with each other. The application of computer technology in the field of cranio and maxillofacial surgery opened a new perspective in the preoperative planning and accurate intraoperative realization of treatment concept.

Bacterial Identification and Monitoring Around Two-Piece Dental Implants by Matrix-Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS).

 Early microbiological diagnosis and treatment of periodontal pathogens is important for successful retention of dental implants.  This study aimed to identify and monitor oral bacterial colonization after successful two-piece dental implants.  In this study, 50 two-piece dental implant subjects were included and assessed clinically, radiographically, and microbiologically.

Quantitative analysis of tumor-associated tissue eosinophils and tumor-associated blood eosinophils in oral squamous cell carcinoma.

Background: Stromal response to cancer is usually characterized by intense lymphoplasmacytic infiltrate. However, recently, the attention has shifted to tumor-associated tissue eosinophils (TATE). Tumor-associated blood eosinophils (TABE) are rare in solid cancers; however, carcinoma of the head and neck shows its prevalence.

Evaluation of the Antimicrobial Efficacy of Herbal Extracts Added to Root Canal Sealers of Different Bases: An Study.

Aim: This study aimed to evaluate and compare the antimicrobial efficacy of root canal sealers of different bases when mixed with herbal extracts.

Materials And Methods: An evaluation of three sealers (Endomethasone, AH plus, Apexit plus) mixed with three herbal extracts [ (), (Nutmeg) and (Miswak)] was done against nine strains of bacteria at various time intervals using the agar diffusion test. Moreover, measurement of the mean zones of inhibition was done.

Comparative Evaluation of Hypotensive and Normotensive Anesthesia on LeFort I Osteotomies: A Randomized, Double-Blind, Prospective Clinical Study.

Introduction: Orthognathic surgery can account for a considerable amount of blood loss since the vascularization of maxillofacial region is such that major bleeding can occur. Intra-bony bleed is often involved as a major aspect of blood loss associated with osteotomies, especially LeFort I osteotomy when performed during orthognathic surgery. This study evolved as a result of the increasing concern to attain a clear surgical field and reduce the duration of surgical procedure and the amount of blood loss associated with orthognathic surgery with the use of controlled hypotension.

Association of gingivitis with children oral health-related quality of life in Lucknow: A cross-sectional study.

Introduction: Gingivitis is codified as the most familiar oral disease in children and teenagers. Several studies reported that most of the children and adolescents have negative impact on quality of life (QoL) due to gingivitis or destructive periodontal disease or poor oral health status. Existing literature in this context on Indian population is sparse.

Prevalence of oral premalignant lesions and conditions among the population of Kanpur City, India: A cross-sectional study.

Background: The habit of smoking and chewing tobacco is associated with various types of oral mucosal lesions and conditions, many of which pose a potential threat to cancer growth. The present study aims to evaluate the prevalence of potentially malignant lesions (PML) and oral cancer in North India and to identify the associated risk factors.

Materials And Methods: A cross-sectional study was carried out in the Department of Oral Medicine and Radiology Rama Dental College Hospital and research center Kanpur over a period of 5 years with1,10,625 patients.

Oral lichen planus in an 8-year-old child: A case report with a brief literature review.

Lichen planus (LP) is a chronic autoimmune condition of uncertain etiopathogenesis and usually affects the skin, oro-genital mucosa, nail and scalp appendages. LP is primarily seen in middle-aged individuals, and oral lesions of LP in children are relatively uncommon. Herewith, we report a case of oral LP in an 8-year-old boy, which regressed well with the treatment modality.

Early and accurate detection of bacterial isolates from dental plaque in subjects with primary, mixed, and permanent dentition by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry technique.

Background: Bacterial colonization of dentition in different age groups can impact prognosis in different dental diseases. Latest diagnostic technique such as matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF) is increasingly being used for accurate identification of bacteria. This study was undertaken to evaluate the MALDI-TOF MS technique to identify bacterial pathogens from dental plaques in subjects with primary, mixed, and permanent dentition.

Evaluation of efficacy of Aloe Vera as a Disinfectant by Immersion and Spray methods on Irreversible Hydrocolloid Impression Material and its Effect on the Dimensional Stability of Resultant Gypsum Cast - An in Vitro Study.

The need to use a natural alternative for disinfecting dental impression materials, which should be biocompatible and effective, led us to evaluate the efficacy of Aloe vera as a disinfectant by immersion and spray method on alginate impression material and its effect on the dimensional stability of the resultant gypsum cast. The efficacy of the disinfection procedures against Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans was evaluated by determining the number of colony-forming units (CFU) recovered after disinfection of alginate discs inoculated with 1x106 CFU for defined intervals with aloe vera solution (99.96%).

Lip synechiae: A rare complication of azithromycin-associated Stevens-Johnson syndrome.

Stevens-Johnson syndrome (SJS) is a severe form of erythema multiforme, is a self-limiting acute inflammatory disease of multifactorial origin, but can also present as a chronic recurrent lesion. It causes a whole plethora of lesions, mostly mucocutaneous. It is a dermatologic emergency that occurs with a spectrum of severity and can result in severe morbidity and mortality.

Oral Health Knowledge, Attitude, and Practice among Nursing Students in the North-Eastern Part of Rajasthan, India.

Background: Professional and paramedical students have a key role in oral health promotion. The aim of this study was to assess oral health-related Knowledge, Attitude, and Practice (KAP) among the nursing students in Rajasthan.

Materials And Methods: A cross-sectional, questionnaire-based study was carried out among 409 nursing students from five different institutes who were selected by simple random sampling.

An In-Vitro evaluation of resin infiltration system and conventional pit and fissure sealant on enamel properties in white spot lesions.

Background: Clinically appearing early caries are referred to as white spot lesions (WSLs). These lesions compromise esthetics and precede cavitation; therefore, they must be halted by effective materials.

Aim: To evaluate and compare the depth of penetration and effect of resin infiltration system (Icon) and other conventional pit and fissure sealants (Clinpro and Embrace) on enamel surface properties of WSLs.

Central mucoepidermoid carcinoma: Case report with review of literature.

Occurrence of central mucoepidermoid carcinoma within the jaw bones from aberrant salivary tissues is extremely rare and accounts for 2%-4% of all central mucoepidermoid carcinoma. Mandible is more commonly affected than maxilla in a ratio of 2:1. The origin of mucoepidermoid carcinoma is controversial and questionable.

Cell cannibalism in oral cancer: A sign of aggressiveness, de-evolution, and retroversion of multicellularity.

Background: According to Darwin's theory of evolution, complex creatures evolve from more simplistic ancestors. Dollo's law of irreversibility states that evolution is irreversible. However, cancer cells tend to follow anti-Dollo's law.

Comparative Evaluation between Single Noncompression Miniplate and Two Noncompression Miniplates in the Treatment of Mandibular Angle Fractures.

This study was conducted to compare the outcome of single noncompression miniplate versus two noncompression miniplates in the treatment of mandibular angle fracture. A total of 40 patients were divided into two groups: Group I (  = 20), patients were treated by single miniplate at superior border of mandible by intraoral approach; Group II (  = 20), patients were treated by one miniplate at superior border of mandible, intraorally, and another at the lateral aspect of angle, transbuccally by trocar and cannula. Comparative evaluation was done at 1, 2, 4, 6, and 12 weeks and 6 months.

Influence of plant extracts mixed with endodontic sealers on the growth of oral pathogens in root canal: An study.

Introduction: Microbes are considered as the primary etiological agents in endodontic diseases. Ways of reducing these agents are root canal debridement and antibacterial filling materials. One of the factors in determining the success of endodontic treatment previously was sealing root canals with materials possessing potent bactericidal effect.

Evaluation of the relative efficacy of autologous platelet-rich fibrin membrane in combination with β-tricalcium phosphate (Septodont- resorbable tissue replacement)™ alloplast versus β-TCP alloplast alone in the treatment of grade II furcation defects.

Introduction: Platelet-rich fibrin (PRF) is considered as the second-generation platelet concentrate, contains combined properties of fibrin, platelets, leukocytes, growth factors, and cytokines that make it as healing biomaterial with incredible potential for hard tissue and soft tissue regeneration. The present study was aimed to evaluate the effectiveness of PRF with β-tricalcium phosphate (β-TCP) graft (R. T.

Collagen Membrane Over Buccal Fat Pad Versus Buccal Fat Pad in Management of Oral Submucous Fibrosis: A Comparative Prospective Study.

Objective: The objective of this study was to assess the effectiveness of collagen membrane as biological dressing over buccal fat pad (BFP) during crucial postoperative healing phase in the surgical management of oral submucous fibrosis (OSMF).

Study Design: The study comprised of 40 patients of OSMF of group IVa (Khanna and Andrade). Patients were randomly divided in two groups (20 patients in each group).