1 results match your criteria: "Sarah Cannon Research Institute; and Tennessee Oncology[Affiliation]"

Pleiotropic activity of systemically delivered angiogenin in the SOD1 mouse model.

Neuropharmacology

May 2018

Department of Physiology and Medical Physics, Centre for the Study of Neurological Disorders, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland. Electronic address:

Loss-of-function mutations in the angiogenin (ANG) gene have been identified in familial and sporadic ALS patients. Previous work from our group identified human ANG (huANG) to protect motoneurons in vitro, and provided proof-of-concept that daily intraperitoneal (i.p.

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