2 results match your criteria: "Sanya Women and Children's Hospital Sanya[Affiliation]"
Endometrial cancer intraoperative sentinel lymph node identification can effectively guide treatment.
Am J Transl Res
October 2023
Department of Obstetrics and Gynecology, Sanya Women and Children's Hospital Sanya, Hainan, China.
Objective: To explore the significance of intraoperative sentinel lymph node (SLN) identification in endometrial cancer.
Methods: We retrospectively analyzed the clinical data of 56 patients with intraoperative SLN recognition (group A) and 50 patients without intraoperative SLN recognition (group B). SLN and pelvic abdominal lymph node distribution, SLN recognition rate, SLN recognition effect, mortality, the incidence of adverse events, and cumulative survival rate were statistically analyzed.
Blocking PARP activity with the inhibitor veliparib enhances radiotherapy sensitivity in endometrial carcinoma.
J Clin Lab Anal
May 2022
Department of Obstetrics and Gynecology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Objective: Our study aimed to investigate the potential clinical utility of a poly(ADP-ribose) polymerase (PARP) inhibitor, veliparib (ABT-888), as a radiosensitizer in the medication of endometrial carcinoma (EC).
Methods: Human Ishikawa endometrial adenocarcinoma cells were treated with veliparib, radiotherapy (RT), or combination treatment. The viabilities, radiosensitivity enhancement ratio (sensitizer enhancement ratio (SER), and apoptosis of Ishikawa cells were, respectively, evaluated by Cell Counting Kit-8 (CCK-8), colony formation experiment, and flow cytometry.