181 results match your criteria: "Santosh Dental & Medical College Hospitals[Affiliation]"

Article Synopsis
  • The study investigates the effectiveness and safety of dentifrices containing Nano silver fluoride (NSF) against the bacteria Streptococcus mutans, which causes tooth decay.
  • Researchers synthesized NSF particles and created dentifrices with varying concentrations of NSF, assessing their antimicrobial properties using an agar diffusion method and cytotoxicity on mouse macrophage cells.
  • Results showed that NSF dentifrices inhibited bacterial growth effectively while also evaluating their impact on cell viability to ensure safety for use in oral health products.
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Background: This systematic review and meta-analysis compared the accuracy of robotic-assisted dental implant placement (r-CAIS) with conventional freehand, static computer-assisted (s-CAIS), and dynamic computer-assisted (d-CAIS) techniques.

Methods: A comprehensive search was conducted in PubMed, Google Scholar, Semantic Scholar, and the Cochrane Library from January 2000 to January 2024. Studies meeting PICOST criteria, including clinical and in vitro studies, were included.

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Background The rising demand for orthodontic services is juxtaposed with concerns regarding economic accessibility for diverse socioeconomic groups. Aim This study aims to investigate the economic accessibility of orthodontic care in India through a comprehensive questionnaire-based approach. Material and methods The survey involved a random sample of 5,000 patients actively seeking orthodontic treatment, recruited from both dental college clinics and private dental practices.

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Background: Attaining adequate osseointegration and mitigating infections are paramount issues in implantology, especially within dental and orthopaedic domains. Titanium implants have been utilised for their biocompatibility and mechanical strength; yet, problems such as peri‑implant infections and inadequate bone integration may undermine their efficacy. Coating titanium implants with iron nanoparticles (FeNp) has surfaced as a promising approach to improve osseointegration and antibacterial characteristics.

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Article Synopsis
  • The study examines the effectiveness of three different matrix systems—Tofflemire, Garrison, and Bioclear—used for Class II composite restorations in premolars and molars, focusing on their ability to create tight proximal contacts and proper contours.
  • Using FDI criteria, the researchers conducted evaluations immediately after restoration placement, employing methods such as flossing and radiographic examination to assess the contact quality and marginal gaps.
  • Statistical analysis indicated significant differences among the matrix systems in terms of the quality of proximal contact and contour, with results processed using SPSS and significance level set at p < 0.05.
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This report chronicles the case of an adolescent female with cleft palate associated severe hypoplastic maxillary Class III deformity. Treatment involved anterior maxillary segmental distraction osteogenesis (AMSDO) in conjunction with pre-distraction and post-distraction orthodontics. Following pre-distraction orthodontics, AMSDO was performed using a customized Hyrax distractor assembly.

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Background: This study aimed to evaluate and compare the efficacy of oral premedication with ibuprofen on the anesthetic efficacy of inferior alveolar nerve block (IANB) using 2% lignocaine and 1:100000 epinephrine in tobacco-chewing (TC) and non-tobacco-chewing (NTC) patients with symptomatic irreversible pulpitis (SIP) during nonsurgical endodontic intervention (NEI).

Methods: This multicenter, prospective, double-blind, two-arm parallel-group randomized controlled trial involving 160 patients was conducted for a period of 9 months. The patients were classified into the study (TC patients) and control (NTC patients) groups, which were subdivided into two subgroups 1 hour before the procedure based on oral premedication with tab ibuprofen 600 mg.

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Efficacy of Apical Negative Pressure Irrigation in Primary Teeth: A Smear Layer Analysis.

Int J Clin Pediatr Dent

June 2024

Unit of Public Health Dentistry, Faculty of Dental Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

Article Synopsis
  • This study evaluated how effectively the Endo-Irrigator Plus (CWAIS) system removes debris from root canals in primary teeth compared to traditional irrigation methods.
  • Twenty-five primary mandibular first molars were tested in five different groups, using various irrigation techniques and analyzing the results using environmental scanning electron microscopy (SEM).
  • The findings revealed that groups using the Endo-Irrigator Plus showed significantly better debris removal, especially in the apical third of the canal, compared to those using only positive pressure irrigation.
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Background: Orthodontic treatment often induces pain, especially post appliance placement. This study compares transcutaneous electrical nerve stimulation (TENS) and acetaminophen for orthodontic pain management.

Materials And Methods: A randomized trial included 120 fixed orthodontic patients divided into three groups (n = 40): Group A received TENS, group B received acetaminophen, and group C was the control.

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Article Synopsis
  • Peripheral giant cell granuloma (PGCG), formerly known as giant cell epulis, is a benign overgrowth in the oral cavity, often related to irritation, and can impact daily functions and psychological well-being when large enough.* -
  • A case study involving a 9-year-old boy highlighted how a sizable PGCG affected his chewing, leading to surgical removal under general anesthesia, with a successful recovery over the following months.* -
  • To achieve optimal healing and prevent recurrence, thorough diagnosis and complete excision of the lesion, along with addressing any irritating factors, are essential.*
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Objective: This prospective study aimed to evaluate the analgesic effects of acetaminophen and Transcutaneous Electric Nerve Stimulation (TENS) therapy for pain control.

Methods: Forty orthodontic patients who underwent fixed orthodontic treatment were randomly assigned to one of 3 groups: (1) acetaminophen, (2) TENS therapy, or (3) control. Pain was evaluated at 12, 24, 36, and 48 hours after the placement of both 0.

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Article Synopsis
  • - Drug-resistant infections are a major medical challenge, and while adaptive lab evolution helps anticipate these issues, it has limitations; novel drug delivery systems (DDSs) aim to address this.
  • - Multi-stimuli responsive DDSs target specific bacterial infection sites by exploiting the acidic conditions of infected tissues, facilitating more effective drug delivery and pathogen elimination.
  • - Recent advancements in nano-drug delivery systems (nDDSs) improve the effectiveness of antimicrobial treatments by targeting and delivering drugs directly to bacterial biofilms, while also exploring new methods like immune modulation and photothermal therapy for enhanced treatment options.
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Article Synopsis
  • - The study aimed to evaluate and compare the antifungal effectiveness of various solutions (3% sodium hypochlorite, 2% chlorhexidine gluconate, ozonated water, and alum water) against specific fungal strains.
  • - Salivary samples from 35 patients were cultured, and the efficacy of each solution was tested using the agar well diffusion method, measuring the diameter of the inhibition zones created by each solution.
  • - Results showed that 3% sodium hypochlorite had the largest inhibitory effect against the fungi, followed by 2% chlorhexidine, while ozonated water had the smallest inhibitory zone.
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A Comparative Evaluation of Herbal Extracts and Triple Antibiotic Paste as Intracanal Medicament against A Microbiological Study.

Int J Clin Pediatr Dent

March 2024

Department of Pediatric and Preventive Dentistry, Santosh Dental College & Hospital, Santosh (Deemed to be University), Ghaziabad, Uttar Pradesh, India.

Article Synopsis
  • The study aims to assess how effective herbal extracts (ginger, turmeric, and nutmeg) are in comparison to modified triple antibiotic paste (MTAP) as treatments for canal infections.
  • A total of 103 samples were tested with various concentrations of herbal extracts and MTAP; combinations of these extracts were also evaluated for their antibacterial properties.
  • Results indicate that the combination of ginger and nutmeg at a 12.5% concentration showed the most effectiveness against bacteria, similar to MTAP's performance.
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Introduction: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. Lifestyle modification is the mainstay of management, however, most patients find it difficult to significantly modify their lifestyle. Mobile health is an innovative healthcare system that has an established role in treating chronic diseases like asthma, cancer and cardiovascular disease.

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Objective: Pigmented fungiform papillae of the tongue (PFPT) are infrequently encountered and inadequately documented pigmented lesions that pose challenges in diagnosis and subsequent treatment planning. The study was aimed at analyzing dentists' knowledge and attitudes regarding PFPT morphologies, to determine diagnosis and subsequent treatment planning.

Methods: A cross-sectional study was conducted among dentists in East Java through an online questionnaire.

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Autologous Concentrate Growth Factor for the Treatment of Endo-Perio Lesion - A Case Report.

Indian J Dent Res

January 2024

Department of Periodontics, Santosh Dental College, Ghaziabad, Uttar Pradesh, India.

Introduction: The success of a combined periodontal and endodontic lesion depends on the elimination of both these disease processes. In the case of a combined endo-perio lesion, endodontic therapy results in healing of the endodontic component of involvement, while the prognosis of teeth would finally depend on the healing of the periodontal structure.

Treatment: This case report evaluates the efficacy of autologous fibrin glue and bone graft, that is, sticky bone in the management of bone defects associated with endo-perio lesion.

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Chronic traumatic ulcers (CTUs) of the oral cavity are frequently brought on by repeated mechanical stress, such as biting or friction from dental appliances, or sharp or broken carious teeth. Although they are frequently disregarded, patients with nonhealing ulcers in the mouth should have CTUs taken into consideration. This report highlights the significance of differential diagnosis and suitable treatment options by discussing a case of a CTU that persisted on the tongue's right lateral border.

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Background The use of endodontic files multiple times can cause fatigue in them and can lead to their separation in the root canal. The purpose of this study was to achieve a reduction in cyclic fatigue stress in a newly introduced nickel-titanium (NiTi) rotary single-file system. The study aimed to determine whether cryotherapy could help reduce cyclic fatigue and stress on rotary files after multiple uses during root canal treatment.

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Background: Oral cancer is a major public health concern worldwide, with oral squamous cell carcinoma (OSCC) being one of its most common subtypes. Despite advances in diagnosis and management of this disease, there remains a need to develop new therapeutic approaches for better outcomes.

Objective: This study aimed to investigate the molecular mechanisms through which cinnamoyl sulfonamide hydroxamate derivatives exert their anticancer effects on OSCC.

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Smart Material for Smarter Dentistry.

J Pharm Bioallied Sci

February 2024

Department of Prosthodontics and Crown and Bridge, Priyadarshini Dental College and Hospital, Thiruvallur, Tamil Nadu, India.

Smart materials encompass a variety of substances, including smart antimicrobial peptides, pit and fissure sealants, impression materials, cement, and sutures. These materials can change properties under specific stimuli such as temperature, stress, moisture, pH, or electric and magnetic fields. These constituents signify the commencement of a novel era or epoch in the field of smart dentistry and exhibit the potential for enhanced efficacy in the future.

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Introduction: The study aimed to evaluate comparability in terms of efficacy, safety and immunogenicity of Sun's ranibizumab biosimilar with reference ranibizumab in patients with neovascular age-related macular degeneration (nAMD).

Methods: This prospective, randomised, double-blind, two-group, parallel-arm, multicentre, phase 3 comparative study included patients with nAMD ≥ 50 years, randomised (in a 2:1 ratio) in a double-blind manner to receive 0.5 mg (0.

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Evaluation and comparison of natural products like triphala, eucalyptus and carvacol with conventional root canal irrigant such as sodium hypochlorite (NaOCL) and Chlorhexidine against persistent root canal pathogens like is of interest. Samples were taken both before irrigation as well as after irrigation. CFU was counted after the plates had been incubated overnight at temperature of 37°C overnight.

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An interesting case-report of ex-ameloblastic carcinoma.

J Oral Maxillofac Pathol

July 2023

Department of Oral and Maxillofacial Pathology and Microbiology, Santosh Dental College, Santosh Deemed to be University, Ghaziabad, Uttar Pradesh, India.

Ameloblastoma (AM) is considered one of the most common lesions of odontogenic origin. Although it is always considered as benign neoplasm, ameloblastic carcinoma (AC) represents its malignant counterpart. It is characterized by the expansion of jaws, rapid growth, and a perforated cortex with well-defined unilocular/multilocular radiolucent lesions.

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Background Cancer is the second most common cause of death. Oral squamous cell carcinoma (OSCC) represents the most frequent of all oral neoplasms. Many treatment modalities such as chemotherapy, radiotherapy, surgery, and immunotherapy are emerging but still, the patients' quality of life is questionable.

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