4 results match your criteria: "Santo Spirito Hospital of Rome[Affiliation]"
Elotuzumab plus pomalidomide and dexamethasone in relapsed/refractory multiple myeloma: a multicenter, retrospective, real-world experience with 200 cases outside of controlled clinical trials.
Haematologica
January 2024
Hematology Section, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari 'Aldo Moro', Bari.
Article Synopsis
- - In the ELOQUENT-3 trial, the combination therapy of elotuzumab, pomalidomide, and dexamethasone (EloPd) showed better results for treating relapsed/refractory multiple myeloma (RRMM) compared to pomalidomide and dexamethasone alone, leading to its approval for specific patients.
- - A real-world study of 200 RRMM cases in Italy confirmed similar effectiveness and manageable side effects for EloPd, with a 55.4% overall response rate and a median progression-free survival of 7 months, though these were lower than results from the ELOQUENT-3 trial.
- - Factors like the number of previous
Chronic lymphocytic leukemia (CLL) is the most common type of leukemia in western countries. The association between CLL and glomerular disease (GD) is rare. The most frequent GD associated with CLL is membranoproliferative membranous glomerulonephritis (GN) (MPGN) (45%) types I and II, followed by membranous glomerulonephritis, with the same reports of immunotactoid glomerulopathy (ITG).
View Article and Find Full Text PDFPulmonary arterial hypertension in a patient with multiple myeloma during carfilzomib treatment: in search of better management.
Tumori
December 2021
Haematology Unit, ASL ROMA 1, Santo Spirito Hospital of Rome, Italy.
Background: Multiple myeloma is a plasma cell dyscrasia accounting for 1% of neoplastic diseases and is the second most common hematologic malignancy after lymphoma. Pulmonary arterial hypertension is characterized by increased blood pressure in the pulmonary circulation and the development of pulmonary vascular remodeling. Increased resistance in the pulmonary vessels strains the right ventricle, leading to right heart failure.
View Article and Find Full Text PDFIdentifying the link between multiple myeloma and neurofibromatosis type I.
Blood Res
September 2020
Haematology Unit, ASL Roma 1, Santo Spirito Hospital of Rome, Italy.