2 results match your criteria: "Santa Maria dela Misericordia Hospital[Affiliation]"

Doxorubicin-loaded nanocarriers: A comparative study of liposome and nanostructured lipid carrier as alternatives for cancer therapy.

Biomed Pharmacother

December 2016

Faculty of Pharmacy, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, 31270-901, Belo Horizonte, Minas Gerais, Brazil. Electronic address:

Nowadays cancer is one of the most common causes of deaths worldwide. Conventional antitumor agents still present various problems related to specificity for tumor cells often leading to therapeutic failure. Nanoscale particles are considered potential alternative to direct access of drugs into tumor cells, therefore increasing the drug accumulation and performance.

View Article and Find Full Text PDF

Feasibility study with 99mTc-HYNIC-βAla-Bombesin(7-14) as an agent to early visualization of lung tumour cells in nude mice.

Nucl Med Commun

April 2016

aDepartment of Pharmacy bDepartment of General Pathology, Biological Sciences Institute, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais cDepartment of Pharmaceutical Sciences, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil dDepartment of Nuclear Medicine, Molecular Imaging, Radiology, NeuroRadiology, Medical Physics, Clinical Laboratory, Microbiology & Pathology, Santa Maria dela Misericordia Hospital, Rovigo, Italy.

Aim: More sensitive and accurate imaging approaches for early detection and therapy monitoring of lung tumours are needed to ameliorate prognosis and outcome. Lung tumours are known to overexpress receptors for bombesin-like peptides. However, thus far, no study has demonstrated the potential role of bombesin-like peptides in identifying A549 lung tumour cells in xenograft animal models.

View Article and Find Full Text PDF