Evaluation of the effect of sodium-glucose cotransporter-2 inhibitor treatment on choroidal vascular parameters in patients with type 2 diabetes mellitus.

Background: To evaluate the effect of sodium-glucose cotransporter-2 inhibitor treatment on choroidal vascular parameters in patients with type 2 diabetes mellitus (T2DM).

Methods: Twenty eyes of 20 patients with T2DM without diabetic retinopathy and 20 eyes of 20 age- and sex-matched patients as the control group were included in the study. The patients were evaluated using enhanced depth imaging optic coherence tomography before treatment and at the third month of treatment.

Sexuality experiences of women with multiple sclerosis reporting overactive bladder: a qualitative study.

Background: To effectively manage sexual dysfunction in women reporting overactive bladder, it is essential to know how patients perceive these problems, their lives, and their strategies.

Aim: In this study we aimed to understand the sexual life experiences of women with multiple sclerosis (MS) who report overactive bladder from their point of view.

Methods: This study included 12 women with MS and was conducted as a qualitative study with a hermeneutic phenomenological framework.

Residual fragment size following retrograde intrarenal surgery: a critical evaluation of related variables.

Given the limited data on the predictive factors of residual kidney stone size after flexible ureteroscopy (fURS), this study aims to investigate the variables affecting residual stone size. The medical records of 642 patients without complications being treated for kidney stones with fURS between July 2014 and May 2022 were reviewed retrospectively, and the information of the 170 patients in whom residual stones were found was recorded. In addition to patient-specific factors and stone characteristics, length of postoperative hospital stay, postoperative fever, and preoperative antiaggregant use were evaluated.

Internet and social media preferences of orthopaedic patients vary according to factors such as age and education levels.

Background: Patients can often access the internet and social media for health information but it is not clear how much they trust and use the information retrieved.

Objective: To investigate the social media and internet use rates and preferences of orthopaedic patients, to reveal to what extent they self-treat, and to probe the affecting factors.

Methods: Two thousand fifty-eight patients admitted to an orthopaedic polyclinic were asked to fill out a survey (voluntarily) consisting of 15 items, to collect demographic data, preference for platforms and sources used, trusted sources, and the extent to which information obtained was used for self-care.

Impact of obesity on peripapillary choroidal thickness, macular choroidal thickness, and lamina cribrosa morphology.

Background: Obesity is known to be a significant risk factor for many ocular diseases. In order to understand the mechanism of obesity-related ocular diseases, we examined the lamina cribrosa morphology, peripapillary choroidal thickness (PPCT), and macular choroidal thickness (MCT) in obese women using optical coherence tomography (OCT).

Methods: This comparative cross-sectional study included the right eyes of 72 obese women and 63 healthy women classified based on body mass index (BMI).

Long-Term Results of Immunogenicity of Booster Vaccination against SARS-CoV-2 (Hybrid COV-RAPEL TR Study) in Turkiye: A Double-Blind, Randomized, Controlled, Multicenter Phase 2 Clinical Study.

The immunogenicity of vaccines decreases over time, causing a need for booster doses. This study aimed to present the long-term (Day 84) immunogenicity results of the double-blind, randomized, controlled, phase II Hybrid COV-RAPEL TR Study (NCT04979949), in which the TURKOVAC or CoronaVac vaccines were used as a booster after the second dose of primary vaccination with CoronaVac. A total of 190 participants from the Hybrid COV-RAPEL TR Study, who had both Day 28 and Day 84 immunogenicity results, were included.

A Comparison of the Effects of Dexamethasone and Methylprednisolone, Used on Level-3 Intensive Care COVID-19 Patients, on Mortality: A Multi-Center Retrospective Study.

Background: Coronavirus disease 2019 (COVID-19) is often a mild disease, usually manifesting with respiratory complaints, and is sometimes mortal due to multiple organ failure. Hyperinflammation is a known COVID-19 component and is associated with organ dysfunction, disease severity and mortality. Controlling hyperinflammatory response is crucial in determining treatment direction.

COVID-19 associated thrombotic microangiopathy.

A limited number of cases of thrombotic microangiopathy (TMA) have previously been reported in association with COVID-19. Our report describes two cases of TMA associated with COVID-19, one of which was successfully treated with eculizumab. The first case was a 23-month-old girl, and the second case was a 9-month-old boy.

Management of primary spontaneous pneumothorax in children: Current practices among Turkish pediatric surgeons.

Background: This study aims to evaluate current practices in the management of primary spontaneous pneumothorax among Turkish pediatric surgeons.

Methods: Between October 2021 and November 2021, an online survey comprising 19 questions was delivered to all members of the Turkish Association of Pediatric Surgeons (TAPS). A total of 74 respondents (42 males, 32 females; mean age: 42.

High AST/ALT Ratio Is Associated with Cardiac Involvement in Acute COVID-19 Patients.

We aimed to assess the effect of AST/ALT ratio on echocardiographic and cardiac magnetic resonance imaging (CMRI) parameters after COVID-19 patients recover. 87 patients with COVID-19 were included in the study. The patients were hospitalized with COVID-19 pneumonia, but the patients did not need intensive care unit follow-up or non-invasive mechanical ventilation support.

Regional Analysis of Inner Retinal Layer Changes in Multiple Sclerosis with and without Optic Neuritis.

Objectives: The study aimed to investigate inner retinal changes in multiple sclerosis (MS) patients by comparing them with healthy controls. The study also aimed to assess regional differences of inner retinal layer involvement in eyes with and without optic neuritis (ON).

Materials And Methods: This retrospective, cross-sectional study consisted of 141 eyes of 74 relapsing-remitting MS patients and 80 eyes of 40 healthy controls.

Clinical Relevance of Choroidal Thickness in Obese and Healthy Children: A Machine Learning Study.

Objectives: To analyze the effect of macular choroidal thickness (MCT) and peripapillary choroidal thickness (PPCT) on the classification of obese and healthy children by comparing the performance of the random forest (RF), support vector machine (SVM), and multilayer perceptrons (MLP) algorithms.

Materials And Methods: Fifty-nine obese children and 35 healthy children aged 6 to 15 years were studied in this prospective comparative study using optical coherence tomography. MCT and PPCT were measured at distances of 500 μm, 1,000 μm, and 1,500 μm from the fovea and optic disc.

The usability of MCP-1, fetuin-A, TAS, and TOS levels in the diagnosis of acute myocardial infarction.

Objective: Our aims were to determine whether the levels of plasma monocyte chemotactic protein-1 (MCP-1), fetuin-A, serum total antioxidant status (TAS), and serum total oxidant status (TOS) are cardiac biomarkers and to clarify their relationship with each other in acute myocardial infarction (AMI).

Patients And Methods: The study included 90 participants: 60 patients with AMI [30 with and 30 without ST-segment elevation myocardial infarction (STEMI)] and 30 cardiac patients without AMI. The diagnostic values of serum Hs-cTnT, MCP-1, fetuin-A, TAS, and TOS levels in predicting AMI were evaluated statistically.

Evaluation of the performance of simple laboratory parameters used in the diagnosis of acute appendicitis.

Background: Acute appendicitis (AA) is one of the most common emergency surgery.

Aim: To evaluate the performance of laboratory parameters used in the diagnosis of AA.

Subjects And Methods: There were two groups.

Central nervous system thrombosis in pediatric acute lymphoblastic leukemia in Turkey: A multicenter study.

Background: In patients with acute lymphoblastic leukemia (ALL), the risk of thromboembolism increases due to hemostatic changes secondary to the primary disease and due to treatment-related factors. In this multicenter study, we aimed to research the frequency of central nervous system (CNS) thrombosis occurring during treatment, hereditary and acquired risk factors, clinical and laboratory features of patients with thrombosis, treatment approaches, and thrombosis-related mortality and morbidity rates in pediatric ALL patients.

Procedure: Pediatric patients who developed CNS thrombosis during ALL treatment from 2010 to 2021 were analyzed retrospectively in 25 different Pediatric Hematology Oncology centers in Türkiye.

Predictive value of sphericity index and other multidetector computed tomography findings in perforated acute appendicitis.

Background: Early radiological prediction and diagnosis of perforated acute appendicitis remain controversial. In the current study, it was aimed to examine the predictive value of multidetector computed tomography (MDCT) findings in perforated acute appendicitis.

Methods: The patients (n=542) who underwent appendectomy between January 2019 and December 2021 were retrospectively evaluated.

Dental Caries, Dental Erosion and Periodontal Disease in Children with Inflammatory Bowel Disease.

There is reportedly a higher prevalence of dental caries and periodontal disease in adults with inflammatory bowel disease (IBD) than in healthy adults. Similar data for children are lacking in the literature. We aimed to evaluate the prevalence of dental erosion, dental caries, and periodontal disease in children with IBD.

Evaluation of prognostic scoring systems in patients hospitalized from the emergency department in a low-income region: northern Syria after internal turmoil as a different universe.

Background: In low-income or underdeveloped countries with conflict and internal unrest, healthcare facilities and staff are limited. For these reasons, it is necessary to use the most straightforward scoring systems to ensure that health facilities and staff are used effectively and to expedite processes through early and effective interventions for patients. In this study, we evaluate and compare the scoring systems used to predict patient prognosis for Emergency Department (ED) patients in northern Syria, which is an area marred by conflict and internal unrest.

Spinal Schwannomas: A Proposal for a New Classification to Aid Surgical Planning.

Background The treatment of spinal schwannomas, which is the most common nerve sheath tumor, is total microsurgical resection. The localization, size and relationship with the surrounding structures of these tumors are crucial in terms of preoperative planning. A new classification method is presented in this study for the surgical planning of spinal schwannoma.