1 results match your criteria: "San Raffaele Scientifi c Institute[Affiliation]"
Gene signatures associated with mouse postnatal hindbrain neural stem cells and medulloblastoma cancer stem cells identify novel molecular mediators and predict human medulloblastoma molecular classification.
Cancer Discov
June 2012
Neural Stem Cell Biology Unit, Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientifi c Institute, Via Olgettina 58, 20132 Milan, Italy.
Article Synopsis
- * By comparing the gene profiles of postnatal hindbrain stem cells and medulloblastoma cancer stem cells (CSC), scientists identified distinct gene signatures that reflect different human medulloblastoma subclasses.
- * The study highlights the significance of developmental genes in medulloblastoma development, suggesting that analyzing gene expression in CSCs could help differentiate patient characteristics beyond just tumor structure analysis.