Microstructural Analysis of the Human Scapula: Mandibular Bone Tissue Engineering Perspectives.

Mandibular bone defect reconstruction remains a significant challenge for surgeons worldwide. Among multiple biodegradable biopolymers, allogeneic bone scaffolds derived from human sources have been used as an alternative to autologous bone grafts, providing optimal conditions for cell recruitment, adhesion, and proliferation and demonstrating significant osteogenic properties. This study aims to investigate the bone microstructure of the human scapula as a source for allogeneic bone scaffold fabrication for mandibular tissue engineering purposes.

Capabilities of Cephalometric Methods to Study X-rays in Three-Dimensional Space (Review).

was a systematic review of modern methods of three-dimensional cephalometric analysis, and the assessment of their efficiency. The scientific papers describing modern diagnostic methods of MFA in dental practice were searched in databases PubMed, Web of Science, eLIBRARY.RU, as well as in a searching system Google Scholar by the following key words: three-dimensional cephalometry, three-dimensional cephalometric analysis, orthodontics, asymmetric deformities, maxillofacial anomalies, 3D cephalometry, CBCT.

Relationship of Iron Deficiency, Anemia and Combination of Iron Deficiency With Anemia With Severity of Manifestations of Chronic Heart Failure. Additional Analysis of the Study "Prevalence of Iron Deficiency in Patients With Chronic Heart Failure in the Russian Federation (J-CHF-RF)".

Aim      To evaluate the role of iron deficiency (ID) identified by various criteria, anemia, and the combination of ID and anemia in determining the severity of the clinical course of chronic heart failure (CHF) in a retrospective analysis of data from 498 patients who participated in the ID-CHF-RF Russian multicenter program.Material and methods  ID was diagnosed by the following three criteria established by the European Society of Cardiology (ESC) and the Russian Society of Cardiology (RSC): 1) ferritin concentration <100 μg/l or ferritin concentration 100-299 μg/l in combination with a decreased transferrin saturation (TS) <20%; 2) ID criteria that showed a high sensitivity and specificity when compared with bone marrow morphology (BMM): TS ≤19.8% or serum iron (SI) ≤13 μmol/l; and 3) a composite index including a ferritin concentration <100 μg/l in combination with TS <20% and SI ≤13 μmol/l.

[Validation of ballistocardiography data for predicting the sleep efficiency in healthy individuals and patients with insomnia].

Objective: To identify valid parameters of heart rate variability (HRV) and musculoskeletal movements based on ballistocardiography data, which allow predicting the sleep efficiency (SE) index in healthy individuals and patients with insomnia.

Material And Methods: Ten healthy individuals and 14 patients with chronic insomnia were examined using polysomnography and ballistocardiography. A regression analysis of the data was carried out, as well as a reliability check of the resulting mathematical model.

[Telemedicine capabilities for monitoring patients with fragility.].

The article presents a review of the literature over the past 10 years on the use of telemedicine capabilities in the management of patients with a focus on patients with fragility. The relevance and validity of the implementation of medical care using telemedicine technologies for patients with fragility are considered. Examples of the most successful solutions for telemonitoring of the selected cohort of patients are given, and both the positive sides and disadvantages of these solutions are considered.

[Thermometrical determination of the postmortem interval by non-linear optimization method].

Objective: To develop and implement an online application for the numerical method of determination of the postmortem interval and its limiting faults, caused by errors of measurement processes, based on the Marshall-Hoare law of cooling and dual thermometry of the corpse's core.

Material And Methods: The numerical search for a minimum of two variables' target function, obtained from the system of non-linear Marshall-Hoare equations, reflecting the dual thermometry of the corpse's core was performed. The code of online program was written in Python 3 programming language.

A modern overview of the process of platelet formation (thrombocytopoiesis) and its dependence on several factors.

Structural and functional alterations in platelets are an actual problem that requires more attention. The treatment of these illnesses proves challenging, inefficient and heavily relies on platelet donations. A difficult task confronting science is producing platelets , which calls for meticulous examination of factors affecting platelet generation.

Biomineralization of Human Genomic DNA into ZIF-8, a Zeolite-Like Metal-Organic Framework.

Unlabelled: was to assess the capabilities of human genomic DNA biomineralization into ZIF-8 metal-organic framework (MOF) preserving DNA sequence integrity after the encapsulation cycle and composite dissolving. The study is an initial stage of the project aimed at developing an abiotic vector to be used when working with native nucleic acids of an arbitrary size based on DNA@ZIF-8 composite.

Materials And Methods: We studied human genomic DNA isolated from lymphocytes of peripheral blood of healthy volunteers using Proba-NK kit (DNA-Technology LLC, Russia).

[Assessment of the radiation risk to health caused by the intake of Cs-137 and Sr-90 radionuclides from food in the able-bodied population of the Samara region].

Monitoring of the content of technogenic radionuclides (Cs-137 and Sr-90) in foods is one of the key areas in ensuring radiation safety of the population, taking into account the current radiation situation. The greatest risk to health is food produced or imported from the territories that have been subjected to man-made radiation accidents. of the research was to assess the radiation risk caused by oral intake of radionuclides based on the study of the actual nutrition of the adult population and contamination of food with Cs-137 and Sr-90 radionuclides.

Application of SBIRT Tools in Managing Alcohol and Drug Use Disorders.

Background: To evaluate the eligibility and feasibility of the "Voice Modules in Narcology" (VMIN) program.

Material And Methods: We developed a computer program to screen for risky alcohol or drug use, utilizing an interactive voice assistant as a motivational component. Given the low detection of such risks during population health examinations and medical check-ups, this program could allow the primary healthcare sector to expand screening coverage for risky alcohol and drug use without additional medical personnel.

Virtual Reality / Augmented Reality (VR/AR) Approach to Develop Social and Communication Skills in Children and Adolescents with Autism Spectrum Disorders Without Intellectual Impairment.

Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that affects a significant proportion of the world's population, particularly children and adolescents. The sensory processing issues can be an evidence-based target for therapeutic/corrective interventions by controlling the intensity and targeted replacement of maladaptive sensory stimuli with neutral stimuli using virtual reality or augmented reality.

Subjects And Methods: We searched for articles on Pubmed.

Visual Snow Syndrome Prevalence Among Young Adults in the Russian Federation: a Research Perspective.

Background: Visual snow syndrome (VSS) is a poorly understood neurological condition of unclear etiology, characterized by visual and non-visual symptoms that reduce quality of life. The objective of our study was to estimate the prevalence of young adults with visual snow in Russia.

Materials And Methods: We conducted an online survey among 1,177 respondents over the age of 18 residing in Russia.