Mannitol for bowel preparation: Efficacy and safety results from the SATISFACTION randomised clinical trial.

Background: Bowel preparation represents a significant issue to high-quality colonoscopy. Oral mannitol requires a single dose, is of low volume, and has a pleasant taste and rapid action.

Aims: This SATISFACTION study compared single-dose (same day) oral mannitol 100 g/750 mL with standard split-dose PEG-ASC2 L (MoviPrep®).

Uncertainty Estimation for Tumor Prediction with Unlabeled Data.

Estimating uncertainty of a neural network is crucial in providing transparency and trustworthiness. In this paper, we focus on uncertainty estimation for digital pathology prediction models. To explore the large amount of unlabeled data in digital pathology, we propose to adopt novel learning method that can fully exploit unlabeled data.

Botanical origins of honeys from pollen analysis during the main honey flow across agro-ecologies in kelala district, South Wollo, Ethiopia.

This study aimed to identify the botanical origins of honey through pollen analysis across agro-ecologies of Kelala district, South Wollo, Ethiopia. Fifteen honey samples were collected from traditional beehives, with 5 samples from each of the highland, midland, and lowland agro-ecologies. Qualitative and quantitative pollen analyses revealed that 22 honeybee plants belonging to 8 families, with no families of poisonous origin, and 3 growth forms were identified.

Identification and functional analysis of novel homozygous LMF1 variants in severe hypertriglyceridemia.

Background: The genetic basis of hypertriglyceridemia (HTG) is complex and includes variants in Lipase Maturation Factor 1 (LMF1), an endoplasmic reticulum (ER)-chaperone involved in the post-translational activation of lipoprotein lipase (LPL).

Objective: The objective of this study was to identify and functionally characterize biallelic LMF1 variants in patients with HTG.

Methods: Genomic DNA sequencing was used to identify biallelic LMF1 variants in HTG patients without deleterious variants in LPL, apolipoprotein C-II (APOC2), glycosylphosphatidylinositol-anchored high-density lipoprotein binding protein 1 (GPIHBP1) or apolipoprotein A-V (APOA5).

[Telemedicine capabilities for monitoring patients with fragility.].

The article presents a review of the literature over the past 10 years on the use of telemedicine capabilities in the management of patients with a focus on patients with fragility. The relevance and validity of the implementation of medical care using telemedicine technologies for patients with fragility are considered. Examples of the most successful solutions for telemonitoring of the selected cohort of patients are given, and both the positive sides and disadvantages of these solutions are considered.

An overview about biomarkers in breast cancer: Insights into the diagnostic and prognostic significance.

Breast cancer (BC) is one of the most significant neoplasms globally due to its high incidence and mortality, particularly among females. As a highly heterogeneous pathology, biomarkers are essential for characterizing specific tumors. Currently, several biological processes are well-described in the context of this neoplasm, such as alterations in BRCA1/2, HER, and pathways involving estrogen and progesterone hormone receptors.

Evaluating the Correlation Between Stimulus Frequency Otoacoustic Emission Group Delays and Tuning Sharpness in a Cochlear Model.

Purpose: A theoretical framework based on coherent reflection and filter theory predicts that the phase-gradient delays of stimulus frequency otoacoustic emissions (SFOAEs) are correlated with tuning sharpness in the mammalian cochlea. In this paper, we use a computational model of the cochlea to test this theory and to evaluate how SFOAE phase-gradient delays may be used to estimate the sharpness of cochlear tuning.

Methods: This study is based on a physiologically motivated model which has been previously shown to predict key aspects of cochlear micromechanics.

Analysis of constraints and opportunities in maize production and marketing in Ethiopia.

Maize, primarily composed of carbohydrates, is the cheapest source of calories. It plays a crucial role in domestic food supply, income generation, and employment. Additionally, maize constitutes a large share of the marketable surplus and is allocated a significant portion of cereal farmland.

Rare giant ovarian thecoma presented as atypical/incomplete Meigs' syndrome: A case image report.

We present a 39-centimeter thecoma with ascites and elevated Ca-125 values which is compatible with an atypical/incomplete Meigs' syndrome. Giant ovarian masses with elevated Ca-125 values and ascites are an alarming combination, although Gynecologists should be aware that there are also benign entities that mimic advanced stage ovarian cancer.

Factors associated with zero vegetable and fruit consumption among Tanzanian children.

Background: Proper nutrition during early childhood is essential for healthy growth and development, yet many children, particularly in low and middle-income countries, fail to meet recommended intake levels of fruits and vegetables. This study aims to assess the factors associated with zero vegetable and fruit (ZVF) consumption among children aged 6-23 months in Tanzania, using data from the 2022 Tanzania Demographic and Health Survey (DHS).

Methods: A weighted sample of 4582 children aged between 6 and 23 months were included in the study.

Proximate composition, some phytochemical constituents, potential uses, and safety of neem leaf flour: A review.

Globally, there is a growing concern about avoiding using artificial compounds in food ingredients, food preservation, and packaging. Among the parts of the neem tree, leaf flour is one of the most commonly used parts in some countries for food and medicinal purposes and is known for containing several nutrients and phytochemicals. In this review, the proximate composition, phytochemical constituents, potential uses, and safety issues of neem leaf flour are discussed.

Penguin colony georegistration using camera pose estimation and phototourism.

Satellite-based remote sensing and uncrewed aerial imagery play increasingly important roles in the mapping of wildlife populations and wildlife habitat, but the availability of imagery has been limited in remote areas. At the same time, ecotourism is a rapidly growing industry and can yield a vast catalog of photographs that could be harnessed for monitoring purposes, but the inherently ad-hoc and unstructured nature of these images make them difficult to use. To help address this, a subfield of computer vision known as phototourism has been developed to leverage a diverse collection of unstructured photographs to reconstruct a georeferenced three-dimensional scene capturing the environment at that location.

Determinants of suboptimal birth spacing among reproductive-age women in Adama district, Ethiopia: a community-based unmatched case-control study.

Background: Birth spacing is crucial for ensuring the health of mothers and their children, as well as determining population growth. Short birth intervals represent a universal public health problem associated with adverse maternal, fetal, neonatal, and child outcomes. However, there is limited information in the study area regarding the determinants of suboptimal birth spacing.

Experimental and theoretical study of the Sn-O bond formation between atomic tin and molecular oxygen.

The merging of the electronic structure calculations and crossed beam experiments expose the reaction dynamics in the tin (Sn, P) - molecular oxygen (O, XΣ-g) system yielding tin monoxide (SnO, XΣ) along with ground state atomic oxygen O(P). The reaction can be initiated on the triplet and singlet surfaces addition of tin to the oxygen atom leading to linear, bent, and/or triangular reaction intermediates. On both the triplet and singlet surfaces, formation of the tin dioxide structure is required prior to unimolecular decomposition to SnO(XΣ) and O(P).

Spontaneous space closure after extraction of young first permanent molar. Retrospective cohort study.

Background: Early compromised first-permanent-molar (FPM) extraction can adversely affect occlusion. However, the current literature does not provide sufficient support for definitive early extraction outcome. This cohort study aimed to evaluate the pattern of post-FPM extraction spontaneous space closure and its pre-extraction indicators.

Lymphoepithelial Carcinoma of the Lung: A Case Report and Review of the Literature.

Lymphoepithelial or lymphoepithelioma-like carcinoma is a poorly differentiated carcinoma located outside the nasopharynx with similar morphologic characteristics to its nasopharyngeal counterpart. Lymphoepithelial carcinoma of the lung is a rare subtype of squamous cell lung carcinoma frequently associated with Epstein-Barr virus (EBV) infection, accounting for approximately 1% of non-small cell lung carcinomas (NSCLC). We herewith present a case of a 78-year-old female patient who was diagnosed with lymphoepithelial carcinoma of the lung, emphasizing its distinct epidemiological features, clinical workup, and histopathological characteristics.

Interrater agreement and reliability of the Bosniak classification for cystic renal masses version 2019.

Background: The Bosniak classification for cystic renal masses has undergone refinements since its inception. The 2019 version provides more objective criteria to enhance interrater agreement but needs validation. This study compares the interrater agreement of the 2005 and 2019 Bosniak classifications for cystic renal masses.