825 results match your criteria: "Salivary Gland Tumors Minor Benign"

Mutational analysis of BRAFV600E in a case of sialadenoma papilliferum of oral cavity.

J Oral Maxillofac Pathol

October 2024

Department of Oral Pathology and Microbiology, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.

This case report presents a rare benign salivary gland tumour called sialadenoma papilliferum. It comprises 3 to 5% of head and neck tumours and about 1% of all minor salivary gland tumours. The focus is on discussing the BRAFV600E mutation analysis and exploring its clinical implications, along with delving into the histopathological differentials.

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Although myoepithelioma is defined as a benign tumour made up primarily of neoplastic myoepithelial cells, its actual histopathological characteristics are highly diverse. It can be considered a rare disease. The most common site of occurrence is the parotid gland, followed by the minor salivary glands of the palate.

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Aims: Esophageal submucosal gland duct adenoma is an extremely rare benign tumour, with only a few reported cases. We conducted the largest single-centre clinical study of esophageal submucosal gland duct adenoma, examining its molecular mechanisms and clinicopathological features.

Methods And Results: Between 2018 and 2023, seven cases of esophageal submucosal gland duct adenoma were identified at a tertiary medical centre; two were female and five were male, aged between 51 and 75 years (mean = 63.

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Article Synopsis
  • Oncocytoma is a rare, benign tumor of the salivary glands, making up less than 2% of all salivary tumors, typically presenting as swelling and rarely recurring.
  • A systematic review analyzed 147 case reports, finding that the average patient was 58.7 years old, with the parotid gland being the most commonly affected, and treatment mainly involved excisional biopsy.
  • The review also noted a slight female predominance in cases and a low association with Birt-Hogg-Dube syndrome, alongside a generally indolent course with few recurrences.
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Diode laser removal of lower lip mucocele: a case report.

Pan Afr Med J

November 2024

Faculty of Dental Medicine of Rabat, Mohammed V University in Rabat, Rabat, Morocco.

Mucocele is a common benign cyst pathology of minor salivary glands of the oral mucosa. The most common location for these lesions is the lower lip. It mainly occurs due to chronic trauma or habit of lip biting or sucking.

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Multiple Benign Minor Salivary Gland Tumours of Nasal Cavity : A Rare Case Report.

Indian J Otolaryngol Head Neck Surg

December 2024

Department of Otolaryngology, Head and Neck Surgery, Government Medical College, Patiala, 147001 India.

Article Synopsis
  • A 60-year-old woman had multiple benign tumors in her minor salivary glands, which caused nasal obstruction, discharge, and postnasal drip.
  • Diagnostic tests showed non-pulsating masses in her nasal cavity and nasopharynx, confirmed to be ectopic minor salivary glands through histopathology.
  • The tumors were successfully removed using endoscopic surgery, leading to symptom resolution and no recurrence detected during follow-up, emphasizing the need for thorough clinical and diagnostic evaluations for nasal issues.
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CARCINOMA-EX- PLEOMORPHIC ADENOMA ARISING WITHIN A PALATAL MINOR SALIVARY GLAND: A CASE REPORT AND REVIEW OF LITERATURE.

West Afr J Med

November 2024

Department of Pathology, Ahmadu Bello University Teaching Hospital (ABUTH), Shika-Zaria, Kaduna State, Nigeria. E-mail: Phone Number: +2348038444939.

Article Synopsis
  • Carcinoma-ex-Pleomorphic Adenoma (CXPA) is a rare malignant tumor that develops from a pre-existing benign Pleomorphic Adenoma, often affecting minor salivary glands like the palate, and has a significant risk of metastasis.
  • A 52-year-old man had a painless, progressively enlarging palatal mass for seven years, which upon examination was found to be non-tender, firm, and adhered to underlying tissues without any prior medical trauma.
  • Pathological analysis confirmed the diagnosis of CXPA, revealing both benign pleomorphic adenoma and malignant features in the same tumor sample, emphasizing the importance of histopathological evaluation for accurate diagnosis.
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A Rare Presentation of Myoepithelioma of the Parotid Gland Manifesting as an Infra-Auricular Swelling.

Cureus

October 2024

Department of Otolaryngology, Head and Neck Surgery, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.

Article Synopsis
  • The report discusses myoepithelioma, an uncommon tumor of the salivary glands, particularly affecting the parotid gland, and typically considered benign.
  • Myoepitheliomas arise from abnormal growth of myoepithelial cells and are classified as a type of pleomorphic adenoma, making their diagnosis challenging due to their complex characteristics.
  • A case of a 42-year-old woman with a lump in the right infra-auricular area is presented, where initial assessments suggested an oncocytic lesion, but further tests confirmed it was a myoepithelioma in the parotid gland.
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Pleomorphic adenoma: Indeed, a versatile tumor.

J Cancer Res Ther

July 2024

Department of General Surgery, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

Article Synopsis
  • Pleomorphic adenoma is the most prevalent benign tumor found in salivary glands, primarily affecting the parotid gland but can also appear in other salivary glands.
  • The tumor exhibits various types of metaplasia, including squamous, osseous, oncocytic, sebaceous, and adipocytic metaplasia, with tyrosine crystalloids sometimes present.
  • The study focuses on these metaplasias and the occurrence of tyrosine crystals in pleomorphic adenomas, highlighting the tumor’s complex nature.
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Article Synopsis
  • Pleomorphic adenoma (PA) is a common benign tumor of the salivary glands, accounting for 80% of salivary gland tumors, but there is limited demographic data available in Tanzania.
  • A retrospective study examined 1824 patient reports from 2016 to 2021, identifying 62 cases (3.4%) of pleomorphic adenoma, with a mean age of 39.9 years and a male-to-female ratio of 1:1.
  • The majority of tumors were found in the palatal minor salivary glands (50%), while the parotid gland accounted for 25.8% of cases, indicating that PA occurs commonly in the 3rd to 5
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Clinical and Morphological Aspects of Aggressive Salivary Gland Mixed Tumors: A Narrative Review.

Diagnostics (Basel)

September 2024

Department of Microscopic-Morphology-Morphopathology, ANATPATMOL Research Center, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square, No. 2, 300041 Timișoara, Romania.

Salivary gland tumors are a rare and heterogeneous group of neoplasms of the head and neck region. The mixed category of these tumors include the following entities: pleomorphic adenoma (PA), carcinoma ex pleomorphic adenoma (CEPA), salivary carcinosarcoma (CS), and metastasizing PA (MPA). The most common benign tumor of the salivary glands is PA.

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Pleomorphic adenoma (PA) is the most prevalent benign salivary gland tumor. Although rare, among the minor salivary glands, palatal PA exhibits the highest incidence. Unlike other benign tumors, PA infiltrates the surrounding tissues, posing challenges for complete removal through conservative measures.

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Article Synopsis
  • Basal cell adenoma is a rare, benign tumor of the salivary gland, mostly found in the parotid gland, and can often be misdiagnosed, requiring thorough histopathological analysis for a correct diagnosis.
  • A case of a 65-year-old woman with a painless mass in the parotid gland, initially suspected to be cancer, ultimately revealed a basal cell adenoma after surgical removal and histopathological examination.
  • The discussion highlights the tumor's characteristics, classification by the WHO, and the necessity for accurate diagnosis and surgical intervention to improve patient outcomes.
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Traumatic Neuroma of the Hard Palate Mimicking a Small Salivary Gland Tumor-A Case Report.

Biomedicines

July 2024

Department of Pediatric Dentistry and Preclinical Dentistry, Wrocław Medical University, Krakowska 26, 50-425 Wrocław, Poland.

Article Synopsis
  • It's crucial to rule out odontogenic origins for any pathologies in the hard palate, and cone-beam computed tomography is essential for diagnosis.
  • Small salivary glands in this area can give rise to both benign and malignant tumors, which may present as solid nodules with healthy-appearing mucosa.
  • The paper discusses a unique case of a traumatic neuroma in the palate, differentiating it from other possible tumors and emphasizing the importance of excisional biopsy for accurate diagnosis and treatment options.
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Article Synopsis
  • - A mucocele is a benign mucous cyst typically found in the minor salivary glands, with two main types: mucus extravasation cysts and retention cysts.
  • - The study analyzed 68 cases, revealing that the majority of patients were young males with a common occurrence in the lower lip, often linked to a history of trauma.
  • - The findings emphasize the importance of recognizing the histopathological features of mucoceles to prevent misdiagnosis in dental practice.
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Sialolipoma of Parotid Gland: A Case Report.

Indian J Otolaryngol Head Neck Surg

August 2024

Department of General Surgery, Nemcare Superspeciality Hospital, Guwahati, Assam India.

Sialolipoma is a rare tumor found within both major and minor saliva. Benign fatty tumors of parotid gland (lipomas) are very unusual, accounting for less than 0.5% of all parotid tumors.

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Article Synopsis
  • Pleomorphic adenoma is a benign tumor primarily found in the salivary glands, especially the parotid, but can also appear in minor glands like the hard and soft palate and upper lip.
  • A case involved a 61-year-old man with a 1.5 cm mass on his upper lip, which was surgically removed and later identified as a pleomorphic adenoma through biopsy.
  • Diagnosing pleomorphic adenoma can be tricky during physical exams, as it might resemble other conditions like an inclusion cyst, leading to possible misdiagnosis and premature treatment decisions.
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Article Synopsis
  • Pleomorphic adenomas (PAs) are the most common benign tumors of the salivary glands, peaking in incidence between ages 40 and 60, and occurring more frequently in females.
  • These tumors primarily develop in the parotid gland (about 80%) but can also arise in minor salivary glands, especially in the palate.
  • The report discusses two unusual cases of PA in minor salivary glands, including an 83-year-old man with a lip swelling and a 45-year-old woman with a palate lesion, both diagnosed through histopathological examination after surgery.
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Article Synopsis
  • * It utilized special staining techniques on samples from 73 tumors, revealing that sialomucin was the most commonly expressed type of mucin across all tumor types.
  • * A significant difference was found in sialomucin levels between benign and malignant tumors, with pleomorphic adenomas showing much higher expression, indicating potential for mucin levels to aid in the diagnosis of salivary gland tumors.
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Canalicular Adenoma in the Parotid Gland: A Rare Case Study.

Ear Nose Throat J

June 2024

Department of Otorhinolaryngology, Al Mouwasat University Hospital, Faculty of Medicine, Damascus University, Damascus, Syria.

Article Synopsis
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The basaloid-spectrum of salivary gland tumors: A focused review with practical diagnostic considerations.

Semin Diagn Pathol

July 2024

Department of Pathology, University of Texas Southwestern Medical Center, 6201 Harry Hines Boulevard, Dallas, TX 75390, United States. Electronic address:

Basaloid salivary gland neoplasms are a diverse and varied group of benign and malignant tumors. The term 'basaloid' is broadly used in reference to cells with elevated nuclear to cytoplasmic ratio, sparse cytoplasm, and hyperchromatic nuclei. However, a subset may also fit within the "small round blue cell tumor" morphologic category or the "biphasic" salivary gland tumor category.

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Article Synopsis
  • Pleomorphic adenoma (PA) is the most common benign tumor in salivary glands and can rarely arise in the nasal septum as a borderline tumor.
  • A case study of a 49-year-old patient with nasal congestion revealed a pink tumor in the left nasal cavity, which was confirmed as PA after endoscopic surgery and histopathological analysis.
  • Post-surgery, regular follow-ups and thorough nasal examinations are important to prevent any recurrence of the tumor.
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