8 results match your criteria: "Salah Azaeiz Institute[Affiliation]"

Advanced artificial intelligence framework for T classification of TNM lung cancer inFDG-PET/CT imaging.

Biomed Phys Eng Express

October 2024

University of Tunis El Manar, Faculty of Medicine of Tunis, Laboratory of Biophysics and Medical Technologies (Higher Institute of Medical Technologies of Tunis), Department of Nuclear Medicine, Salah Azaiez Institute, Tunis, Tunisia.

Article Synopsis
  • - The integration of AI in lung cancer management aims to enhance diagnostic and treatment strategies by automatically segmenting lung tumors and classifying lung cancer using PET/CT imaging.
  • - A modified ResNet-50 model was utilized for accurate tumor segmentation, producing 3D models that help visualize tumor boundaries for better treatment planning.
  • - The study's AI framework showed strong performance in classifying T stages of lung tumors, which is crucial for determining treatment options and assessing prognosis, ultimately improving patient outcomes.
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Immunometabolism mRNA expression phenotypes and reprogramming of CD14 in T2DM with or without CVD.

Int Immunopharmacol

September 2023

Unit of Immunology and Microbiology Environmental and Carcinogenesis [IMEC], Faculty of Sciences of Bizerte, Zarzouna7021, University of Carthage, Bizerte, Tunisia.

Background/aim: Type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD) have a significant impact on the expression of genes in peripheral blood mononuclear cells (PBMCs). The primary objective of this study was to investigate the role of two signaling pathways, STAT1/6, and two important modulators of immunometabolism, leptin and PPARs, in the development of T2DM with and without CVD. Furthermore, the study aimed to assess the correlation between these factors and the dynamics of CD14 in PBMCs.

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Introduction: Cystic lymphangioma (CL) is a benign tumor originating from the lymph vessels. Lymphangiomas in the abdominal cavity are extremely rare, particularly in adults.This article was designed to study the epidemiological, diagnostic difficulties, and therapeutic principles of intra-abdominal cystic lymphangioma (ACL) in adults.

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Article Synopsis
  • SMARCA4-deficient thoracic sarcoma (SMARCA4-DTS) is a new and aggressive form of sarcoma diagnosed in a 44-year-old man after he had surgery for a perforated small intestine.
  • A CT scan showed a mass in the mediastinum and lungs, and histopathological tests revealed a malignant tumor with specific cell types and significant necrosis.
  • The confirmation of SMARCA4-DTS was made through extensive immunohistochemistry, highlighting the need to include this diagnosis when examining tumors with similar features, particularly in patients with metastasis and thoracic masses.
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Alterations in colonic mucus secretion are linked to the induction and maintenance of inflammation during inflammatory bowel disease (IBD) and its progression to colorectal cancer (CRC). MUC1, a multifunctional glycoprotein, is the best studied cell surface mucin in mouse models of IBD and CRC. However, little information on MUC1 expression and localization in different types of pathologic human colon mucosa is available.

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Background: Cardiac tumors are a very rare entity. Leiomyosarcoma represents less than 1% of cases.

Case Presentation: a 51-year-old woman diagnosed with primary left atrium leiomyosarcoma.

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Orbital tumor revealing a systemic sarcoidosis.

Acta Med Iran

September 2015

Department of Pathology, Salah Azaeiz Institute, Bab Saadoun, 1006 Tunis, Tunisia.

Ocular involvement is seen in approximately 25% of patients with sarcoidosis. Uveitis is the most common ocular manifestation, but sarcoidosis may involve any part of the eye. Orbital manifestations of sarcoidosis are uncommon with few series in the literature.

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Testicular synovial sarcoma: a case report.

Cancer Biol Med

December 2012

Department of Medical Oncology, Salah Azaeiz Institute, Tunis 1006, Tunisia.

This paper reports a case of testicular synovial sarcoma with molecular genetic analysis. A 24-year-old male presented with painless scrotal mass. Ultrasonography showed a heterogeneous mass of 66 mm × 34 mm in size involving the inguinal region.

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