3 results match your criteria: "Sainte-Clotilde Clinic[Affiliation]"
The Potential of Human Pulmonary Mesenchymal Stem Cells as Vectors for Radiosensitizing Metallic Nanoparticles: An In Vitro Study.
Cancers (Basel)
September 2024
Laboratoire Interdisciplinaire de Recherche en Santé (LIRS), RunResearch, Sainte-Clotilde Clinic, 127 Route de Bois de Nèfles, 97400 Saint-Denis, Reunion Island, France.
Article Synopsis
- Metallic nanoparticles (NPs), specifically core-shell FeO@Au NPs, were evaluated for their effects on human pulmonary mesenchymal stem cells (HPMSCs), showing no impact on cell viability at a concentration of 100 µg/mL.
- Gene expression in HPMSCs was altered after exposure, with significant changes noted at 72 hours, including decreased proinflammatory cytokines, but no effects on certain key tumor-related gene expressions.
- The study concluded that FeO@Au NPs do not harm HPMSCs and may be a promising method for targeted delivery to tumors alongside radiation therapy.
Reasons for the Failure of Platelet Function Testing to Adjust Antiplatelet Therapy: Pharmacodynamic Insights From the ARCTIC Study.
Circ Cardiovasc Interv
November 2019
Sorbonne University, ACTION Study Group, INSERM UMRS 1166, Cardiology Institute, Pitié-Salpêtrière (AP-HP) University Hospital, Paris, France (B.L., J.S., Y.Y., G.M., J.-P.C.).
Background: In the ARCTIC trial (Assessment by a Double Randomization of a Conventional Antiplatelet Strategy Versus a Monitoring-Guided Strategy for Drug-Eluting Stent Implantation and of Treatment Interruption Versus Continuation One Year After Stenting), treatment adjustment following platelet function testing failed to improve clinical outcomes. However, high-on-treatment platelet reactivity (HPR) is considered as a predictor of poor ischemic outcome. This prespecified substudy evaluated clinical outcomes according to the residual platelet reactivity status after antiplatelet therapy adjustment.
View Article and Find Full Text PDFIatrogenic cerebral air embolism: importance of an early hyperbaric oxygenation.
Intensive Care Med
May 2002
Department of Cardiology, Sainte Clotilde Clinic and Intensive Care Unit, Felix Guyon Hospital, Saint Denis, Réunion Island, France.
Objectives: To assess the relationship between the time period before hyperbaric oxygenation therapy (HBO) and clinical outcome in patients with iatrogenic cerebral air embolism.
Design And Setting: Retrospective study in a hyperbaric chamber and medical intensive care unit of a university hospital.
Patients: All patients with air embolism from 1980 to 1999.