4 results match your criteria: "Saint-Louis Hospital and Paris-7 University[Affiliation]"
Article Synopsis
- This study investigates the effectiveness of tepotinib, a MET inhibitor, in treating hepatocellular carcinoma (HCC) with gene amplification (amp), specifically in patients showing high levels of amp (≥10). * -
- Preclinical tests on patient-derived tumor models showed tepotinib caused nearly complete tumor regression in cases with high-level amp, while clinical trials indicated that 11 out of 15 patients with amp experienced disease control. * -
- The findings suggest that high-level amp might drive cancer growth in HCC and that tepotinib could be an effective treatment option for these patients. *
A communication strategy and brochure for relatives of patients dying in the ICU.
N Engl J Med
February 2007
Saint-Louis Hospital and Paris 7 University, Assistance Publique-Hôpitaux de Paris, France.
Background: There is a need for close communication with relatives of patients dying in the intensive care unit (ICU). We evaluated a format that included a proactive end-of-life conference and a brochure to see whether it could lessen the effects of bereavement.
Methods: Family members of 126 patients dying in 22 ICUs in France were randomly assigned to the intervention format or to the customary end-of-life conference.
Burnout syndrome in critical care nursing staff.
Am J Respir Crit Care Med
April 2007
Medical ICU, Saint-Louis Hospital and Paris 7 University, Assistance Publique, Hôpitaux de Paris, Paris, France.
Rationale: Burnout syndrome (BOS) associated with stress has been documented in health care professionals in many specialties. The intensive care unit (ICU) is a highly stressful environment. Little is known about BOS in critical care nursing staff.
View Article and Find Full Text PDFThe prognosis of acute respiratory failure in critically ill cancer patients.
Medicine (Baltimore)
November 2004
From Medical Intensive Care Unit, Biostatistics Department, Respiratory Department, Department of Pathology, Saint-Louis Hospital and Paris 7 University. Assistance Publique, Hôpitaux de Paris, France.
Acute respiratory failure (ARF) in patients with cancer is frequently a fatal event. To identify factors associated with survival of cancer patients admitted to an intensive care unit (ICU) for ARF, we conducted a prospective 5-year observational study in a medical ICU in a teaching hospital in Paris, France. The patients were 203 cancer patients with ARF mainly due to infectious pneumonia (58%), but also noninfectious pneumonia (9%), congestive heart failure (12%), and no identifiable cause (21%).
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