33 results match your criteria: "Saint Joseph Saint Luc Hospital[Affiliation]"

Background: Despite vaccination, patients receiving anti-CD20 monoclonal antibodies (mAbs) for multiple sclerosis (MS) or neuromyelitis optica spectrum disorders (NMOSD) have an increased risk of developing severe or protracted COVID-19. The aim of this study was to describe the effect of COVID-19 convalescent plasma (CCP) in patients with MS or NMOSD exposed to anti-CD20 and infected by SARS-CoV-2.

Methods: This French national, retrospective cohort study was conducted between November 2020 and June 2023.

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The objective of this study is to assess the quality of life and how to return to work after burns in adults. We conducted a monocentric, observational, prospective and open study in an intensive care burn unit. Patients aged between 18 and 65 years old were enrolled.

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Prognostic value of 18 FDG-PET at diagnosis and follow-up in giant cell arteritis: An observational restrospective study.

Eur J Intern Med

August 2024

Department of Internal Medicine and Clinical Immunology, Referral Center for Rare Systemic Autoimmune and Autoinflammatory Diseases (MAIS), Dijon Bourgogne University Hospital, Dijon, France; INSERM, EFS BFC, UMR 1098, RIGHT Graft-Host-Tumor Interactions/Cellular and Genetic Engineering, Bourgogne Franche-Comté University, Dijon, France. Electronic address:

Objectives: To evaluate the ability of FDG PET/CT, at diagnosis of giant cell arteritis (GCA) and during follow-up, to predict occurrence of relapse in large-vessel GCA (LV-GCA).

Methods: We conducted a retrospective study using the French Study Group for Large-Vessel Vasculitis (GEFA) network. Data from patients with LV-GCA diagnosed by PET/CT and who had PET/CT in the following year were collected.

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Introduction: This study aimed to provide an updated analysis of the different prognostic trajectories of patients with anti-melanoma differentiation-associated gene 5 (MDA5) antibodies.

Methods: Among a cohort of 70 patients, baseline characteristics and phenotypes, treatments and outcomes were analyzed. A Cox proportional hazards model was used to identify factors associated with poor outcomes, i.

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Endoscopic treatment of diastasis recti: Training method and literature review.

Ann Chir Plast Esthet

June 2023

Department of Plastic and Reconstructive Surgery, Croix-Rousse University Hospital, Hospices Civils de Lyon, University of Lyon I, UCBL 1, 103, Grande Rue de la Croix-Rousse, 69004 Lyon, France. Electronic address:

Introduction: Endoscopic treatment of diastasis rectus abdominis offers the possibility of correcting the condition without complete abdominoplasty. The purpose of this study was to develop a training method on fresh cadavers models based on a literature review on this surgery.

Material And Methods: The endoscopic procedure considered involved the insertion of a 10mm suprapubic trocar and of 5mm trocars in each iliac fossae.

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Introduction: Anterior shoulder dislocation is a common reason for consultation at the emergency department (ED). Hypnosis could be a safe and effective alternative therapy for pain relief during shoulder dislocation reduction but nowadays, evidence is not sufficient. The main objective of this study is to show that reduction under hypnosis is associated with a decrease in the use of analgesic compared with usual care.

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Objective: Dermatomyositis associated with anti-MDA5 autoantibodies (DM-MDA5+) is a rare autoimmune disease usually characterized by skin involvement, often-severe lung involvement, and general features. Several reports of infections have been described, sometimes early after the introduction of immunosuppressive therapy. We studied the infection risk in a DM-MDA5+ population.

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Background: Pelvic organ prolapse (POP) affects about half of the women and affects their quality of life. The current study is, therefore, aimed at determining the prevalence and surgical outcomes of severe stage POP at Jimma University medical center from November 2016 to May 2018.

Method: A Hospital-based cross-sectional study was conducted on all patients with stage 3 and 4 POP, who were admitted, and had surgery.

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Saliva Quantification of SARS-CoV-2 in Real-Time PCR From Asymptomatic or Mild COVID-19 Adults.

Front Microbiol

January 2022

Health, Systemic, Process, UR4129 Research Unit, University Claude Bernard Lyon 1, University of Lyon, Lyon, France.

The fast spread of COVID-19 is related to the highly infectious nature of SARS-CoV-2. The disease is suggested to be transmitted through saliva droplets and nasal discharge. The saliva quantification of SARS-CoV-2 in real-time PCR from asymptomatic or mild COVID-19 adults has not been fully documented.

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Objectives: To determine if commercially available mouthwash with β-cyclodextrin and citrox (bioflavonoids) (CDCM) could decrease the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) salivary viral load.

Methods: In this randomized controlled trial, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) PCR-positive patients aged 18-85 years with asymptomatic to mild coronavirus disease 2019 (COVID-19) symptoms for <8 days were recruited. A total of 176 eligible patients were randomly assigned (1:1) to CDCM or placebo.

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Background: The indication for antibiotic prophylaxis in burn patients remains highly controversial, with no consensus having been reached. The objective of antibiotic prophylaxis is to reduce the risk of postoperative local and systemic infections. Burn surgery is associated with a high incidence of bacteremia, postoperative infections, and sepsis.

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Desquamative interstitial pneumonia induced by metal exposure. A case report and literature review.

Sarcoidosis Vasc Diffuse Lung Dis

November 2020

Service de Pneumologie et d'explorations fonctionnelles respiratoires, CHU Bretonneau, Tours, France.

Background: Forms of interstitial pneumonia secondary to exposure to an air-contaminant are varied and so far, insufficiently described.

Objectives/methods: We report here a case of a 57-year-old patient managed in our department for the exploration of MRC grade 2 dyspnoea and interstitial pneumonia. He mentioned multiple occupational and domestic exposures such as hens' excrements, asbestos and metal particles; he also had a previous history of smoking.

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Bedside Ultrasound for Weaning from Mechanical Ventilation: The Diaphragm Is Not Enough!

Anesthesiology

May 2020

From the Intensive Care Unit, Saint Joseph Saint Luc Hospital, Lyon, France (E.V.) University Paris Est Créteil (UPEC), Mondor Institute of Biomedical Research (IMRB), Clinical Research Group on Cardiovascular and Respiratory Manifestations of Acute Lung Injury and Sepsis (CARMAS), Créteil, France (E.V., A.M.D.) Greater Paris Public Hospitals (Assistance Publique-Hôpitaux de Paris), Henri Mondor University Hospital, Ageing Thorax-Vessels-Blood Department, Departments of Intensive Care, Créteil, France (A.M.D.) National Institute of Health and Research (INSERM), Unit U955, Team 13, Créteil, France (A.M.D.).

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Diagnostic Accuracy of Diaphragm Ultrasound in Detecting and Characterizing Patient-Ventilator Asynchronies during Noninvasive Ventilation.

Anesthesiology

June 2020

From the Intensive Care Unit, Saint Joseph Saint Luc Hospital, Lyon, France (E.V.) University Paris Est Créteil (UPEC), Mondor Institute of Biomedical Research (IMRB), Clinical Research Group on Cardiovascular and Respiratory Manifestations of Acute Lung Injury and Sepsis (CARMAS), Créteil, France (E.V., A.F.H., A.M.D., G.C.) Greater Paris Public Hospitals (Assistance Publique-Hôpitaux de Paris), Henri Mondor University Hospital, Ageing Thorax-Vessels-Blood Department, Departments of Intensive Care, Créteil, France (A.F.H., A.M.D., G.C.) National Institute of Health and Research (Institut National de la Santé et de la Recherche Médicale; INSERM), Clinical Research Center 1430, Henri Mondor University Hospital, Créteil, France (P.LC.) National Institute of Health and Research (INSERM), Unit U955, Team 13, Créteil, France (A.M.D., G.C.).

Article Synopsis
  • Noninvasive ventilation for acute respiratory failure can face issues like patient-ventilator asynchronies, which may result from leaks in the interface, affecting patient comfort and ventilation efficacy.
  • The study introduces two innovative methods using ultrasound to measure diaphragm movement and airway pressure to detect these asynchronies, specifically during deliberately induced leaks in healthy individuals.
  • The results indicated high sensitivity for detecting asynchronies, with diaphragm excursion and thickening methods showing comparable or superior performance to traditional flow/pressure analysis, highlighting their potential for improving noninvasive ventilation monitoring.
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Management of severe thermal burns in the acute phase in adults and children.

Anaesth Crit Care Pain Med

April 2020

Department of Anaesthesiology, Critical Care and Burn Centre, Lariboisière-Saint-Louis Hospitals, DMU Parabol, AP-HP Nord, University of Paris, Paris, France; Inserm UMR-S 942, Cardiovascular Markers in Stress Conditions (MASCOT), University of Paris, Paris, France; Department of Research, University of Ottawa Heart Institute, Ottawa, ON, Canada.

Objectives: To provide recommendations to facilitate the management of severe thermal burns during the acute phase in adults and children.

Design: A committee of 20 experts was asked to produce recommendations in six fields of burn management, namely, (1) assessment, admission to specialised burns centres, and telemedicine; (2) haemodynamic management; (3) airway management and smoke inhalation; (4) anaesthesia and analgesia; (5) burn wound treatments; and (6) other treatments. At the start of the recommendation-formulation process, a formal conflict-of-interest policy was developed and enforced throughout the process.

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Myocardial ischemia during ventilator weaning: a prospective multicenter cohort study.

Crit Care

September 2019

Medical Intensive Care Unit, DHU A-TVB, Henri Mondor University Hospital, Assistance Publique - Hôpitaux de Paris, Créteil, F-94010, France.

Article Synopsis
  • The study looked at why some patients having trouble breathing on their own after using a machine (mechanical ventilation) fail the process called weaning.
  • They found that more than half of the patients had a problem called pulmonary edema, which is when fluid stays in the lungs caused by heart issues.
  • The researchers didn’t find a strong link between another heart problem called cardiac ischemia and the issues with weaning, meaning the heart problem wasn't the main reason patients had trouble breathing again.
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Objective: To determine the ophthalmological and extra-ophthalmological clinical characteristics and visual prognosis of patients with sarcoid uveitis in different ethnic groups.

Methods: We retrospectively analysed the data from patients with sarcoid uveitis seen at two departments of Ophthalmology between December 2003 and December 2017. Patients presented biopsy-proven sarcoidosis and/or presumed sarcoid uveitis based on the following criteria: compatible thoracic imaging, associated with elevated angiotensin-conversion enzyme (ACE) and/or lymphocytic alveolitis on bronchoalveolar lavage fluid analysis (> 15% lymphocytes and CD4/CD8 > 3.

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Background: Colistin resistance in Acinetobacter baumannii often results from mutational activation of the two-component system PmrAB and subsequent addition of phospho-ethanolamine (pEtN) to lipooligosaccharide by up-regulated pEtN transferase PmrC.

Objectives: To characterize mechanisms of colistin resistance independent of PmrCAB in A. baumannii.

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Atrophy of Diaphragm and Pectoral Muscles in Critically Ill Patients.

Anesthesiology

September 2019

From the Intensive Care Unit (E.V., S.R., C.P.) Commission Innovation Recherche (E.V., F.D.) Department of Anesthesiology (A.R.), Saint Joseph Saint Luc Hospital, Lyon, France AP-HP (Greater Public Hospitals in Paris), Henri Mondor University Hospital, DHU A-TVB, Medical Intensive Care, Creteil, France (G.C., A.M.D.) Paris Est Creteil University, Creteil School of Medicine, IMRB, GRC CARMAS, Creteil, France (G.C., A.M.D.) INSERM, U955 Unit, Creteil, France (G.C., A.M.D.).

What We Already Know About This Topic: Muscle atrophy is common in the critically ill, and diaphragm atrophy occurs during mechanical ventilation. It is not known whether wasting of diaphragm and nondiaphragm muscle is related.

What This Article Tells Us That Is New: Ultrasound was used for serial assessment of diaphragm and pectoral muscle in 97 critically ill patients.

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Objective: To evaluate the efficacy of NovaSure radiofrequency global endometrial ablation (GEA) in adenomyosis.

Study Design: We conducted a monocentric longitudinal cohort study at Croix-Rousse University Hospital (Lyon, France). Inclusion criteria were symptomatic adenomyosis resistant to drug therapy (dysmenorrhea and abnormal uterine bleeding (AUB)), for whom Novasure GEA was considered.

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Estimation of blood loss during adult burn surgery.

Burns

September 2018

Burn Intensive Care Unit, Saint Joseph Saint Luc Hospital, 20 quai Claude Bernard, 69007 Lyon, France.

Introduction: Large burns excision and graft can produce major blood loss. The main objective of this study is to evaluate the blood loss in relation with the excision size in square centimeters (cm) in adults.

Patients And Methods: We conducted a monocentric, observational, prospective and open study in a burn intensive care unit.

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Purpose: ULISSE is the only study that prospectively assessed the efficiency of a standardized strategy, compared to an open strategy for the etiologic diagnosis of uveitis. Our aim was to evaluate the diagnostic yield of the tests prescribed in the ULISSE study to clarify their relevance.

Methods: ULISSE is a non-inferiority, prospective, multicenter and cluster randomized study.

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