Influence of gender on clinical presentation, management practices and outcomes of ocular syphilis.

Ocular syphilis is a re-emerging inflammatory eye disease with a clear gender imbalance, disproportionately affecting men. We investigated the impact of gender on the presentation, management practices and clinical outcomes of this condition. Data generated from a study of patients consecutively diagnosed with ocular syphilis who attended a subspecialist uveitis service at one of four hospitals in Brazil over a 30-month period were disaggregated for analysis by gender.

Vision-related quality of life in patients treated for ocular syphilis.

Multiple studies have showed negative impact of non-infectious uveitis on quality of life (QoL). Less is understood regarding life experiences in patients with infectious uveitis. We investigated vision-related QoL in individuals who had recovered from ocular syphilis.

Impact of gender on clinical features and outcomes of ocular toxoplasmosis.

Aim: To investigate the effect of gender on the clinical features and outcomes of ocular toxoplasmosis.

Methods: 262 patients (139 women and 123 men) presenting to a tertiary referral uveitis service in Ribeirão Preto, Brazil, with serological and clinical evidence of ocular toxoplasmosis were prospectively enrolled in an observational study. Predefined data items including demographics, descriptors of uveitis and ocular toxoplasmosis, best-corrected visual acuity and ocular complications were disaggregated by gender and compared statistically.

Comparison of Retinal Structure Using Optical Coherence Tomography Angiography between Persons with and without HIV Infection.

HIV retinal microangiopathy is an important predictor for increased risk of mortality. Optical coherence tomography angiography (OCTA) can investigate microvascular changes resulting from retinal diseases. Study included 25 persons with HIV and 25 healthy persons.

Optical Coherence Tomography Findings in Ocular Syphilis Involving the Posterior Segment of the Eye.

Purpose: To analyse posterior segment optical coherence tomography (OCT) findings in ocular syphilis.

Methods: Medical records of 54 patients presenting consecutively with syphilitic uveitis were reviewed. Vitreous, retina and choroid (one eye/patient) were assessed by spectral-domain OCT on presentation (54 eyes) and after treatment (31 eyes).

Brillouin microscopic depth-dependent analysis of corneal crosslinking performed over or under the LASIK flap.

Purpose: To determine the impact of corneal crosslinking (CXL) performed over the laser in situ keratomileusis (LASIK) flap using the Standard CXL (S-CXL) protocol or under the flap after flap lift (flap-CXL) on regional corneal stiffness using Brillouin microscopy.

Setting: University of Southern California Keck School of Medicine, Los Angeles, California, and Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA.

Design: Laboratory ex vivo experiment.

Toric Artisan after transepithelial topography-guided photorefractive keratectomy for higher-order aberrations following intrastromal corneal ring segments in keratoconus - Trioptics.

We report a case of a 40-year-old female with keratoconus and high myopia who had previous ICRS implantation in both eyes (OU) and was intolerant to contact lenses. Manifest refraction was -8.50 -1.

Optimized CorT Total to compare Scheimpflug vs dual Scheimpflug/Placido imaging devices.

Purpose: To compare the manufacturer-provided measures of total corneal power (TCP) generated by Scheimpflug and dual Scheimpflug/Placido imaging compared with corneal topographic astigmatism calculated on the basis of measured TCP data (CorT Total).

Setting: Emory University, Atlanta, Georgia, USA.

Design: Retrospective case series.

Late-onset corneal haze after intrastromal corneal ring implantation in an eye with previous topography-guided PRK.

Purpose: To report a case of late-onset corneal haze 3 months after intrastromal corneal ring segment (ICRS) implantation in an eye with previous transepithelial topography-guided photorefractive keratectomy (TG-PRK).

Observations: A 40-year-old woman with stable keratoconus for 10 years underwent limited TG-PRK with mitomycin C in both eyes for mixed astigmatism. After four years, with atopic symptoms worsening and eye rubbing, the patient presented keratoconus progression in the left eye with increased irregular astigmatism.

Late progressive corneal flattening, haze and visual loss after eccentric crosslinking for Pellucid marginal degeneration.

Purpose: Pellucid marginal degeneration (PMD) is a rare disease that is often mistaken for keratoconus but can similarly be treated with corneal collagen crosslinking (CXL). We report a case followed though 6 years of progressive irregular corneal flattening and thinning in both eyes (OU) after eccentric CXL for PMD.

Observation: A 46-year-old man with bilateral PMD and corrected distance visual acuity (CDVA) of 20/20 (-2.

Optical behavior of the eye implanted with extreme intraocular lens powers.

Purpose: To evaluate the induced ocular aberrations after cataract surgery with extreme low- powered and high-powered spherical monofocal intraocular lenses (IOLs) using a new pyramidal wavefront sensor aberrometer.

Setting: Vissum Instituto Oftalmológico, Alicante, Spain.

Design: Prospective observational comparative study.

Corneal higher-order aberrations measurements: Comparison between Scheimpflug and dual Scheimpflug-Placido technology in keratoconic eyes.

Purpose: To compare the difference and agreement of corneal higher-order aberrations (HOAs) in keratoconic eyes using Scheimpflug and dual Scheimpflug-Placido imaging systems.

Setting: Emory University, Atlanta, Georgia, and the University of Southern California, Los Angeles, California, USA.

Design: Retrospective between-devices reliability and agreement study.

Current ophthalmology practice patterns for syphilitic uveitis.

Background: Syphilitic uveitis is re-emerging alongside the systemic infection. In July 2017, an international group of uveitis-specialised ophthalmologists formed the International Ocular Syphilis Study Group to define current practice patterns.

Methods: 103 Study Group members based in 35 countries completed a 25-item questionnaire focused on case load, clinical presentations, use and interpretation of investigations, treatment and clinical indicators of poor prognosis.

Effectiveness of Treatments for Ocular Toxoplasmosis.

: To evaluate the effectiveness of treatments for ocular toxoplasmosis (OT).: A review of charts was conducted from patients who experienced an active episode of OT treated at the Federal University of São Paulo and associated sites. OT charts were reviewed to determine treatment effectiveness based on clinical judgment, taking clinical course and outcome into consideration in addition to change in best-corrected visual acuity.

Distinguishing Highly Asymmetric Keratoconus Eyes Using Dual Scheimpflug/Placido Analysis.

Purpose: To identify the best metrics or combination of metrics that provide the highest predictive power between normal eyes and the clinically unaffected eye of patients with highly asymmetric keratoconus using data from a Dual Scheimpflug/Placido device.

Design: Retrospective case-control study.

Methods: Combined Dual Scheimpflug/Placido imaging was obtained from the Galilei G4 device (Ziemer Ophthalmic Systems AG, Port, Switzerland) in 31 clinically unaffected eyes with highly asymmetric keratoconus and 178 eyes from 178 patients with bilaterally normal corneal examinations that underwent uneventful LASIK with at least 1 year follow-up.

Higher-order aberration measurements: Comparison between Scheimpflug and dual Scheimpflug-Placido technology in normal eyes.

Purpose: To compare higher order aberrations (HOAs) in normal eyes between a Scheimpflug imaging system (Pentacam HR) and dual Scheimpflug-Placido imaging system (Galilei G4).

Setting: Emory University, Atlanta, Georgia, and the University of Southern California, Los Angeles, USA.

Design: Retrospective case series.

Net technique for intraocular lens support in aphakia without capsular support.

Background: This paper describes a modified surgical technique for intraocular lens implantation in aphakic eyes with no capsular support.

Methods: Retrospective case series. Seventeen eyes of 17 aphakic patients with no capsule support underwent intraocular lens (IOL) implantation using a standardized technique in which a net was created at the ciliary sulcus plane with two threads forming a net pattern.

Accelerated corneal collagen crosslinking: Technique, efficacy, safety, and applications.

Unlabelled: Corneal collagen crosslinking (CXL) is an approach used to increase the biomechanical stability of the stromal tissue. Over the past 10 years, it has been used to halt the progression of ectatic diseases. According to the photochemical law of reciprocity, the same photochemical effect is achieved with reduced illumination time and correspondingly increased irradiation intensity.

Predictability and Vector Analysis of Laser In Situ Keratomileusis for Residual Errors in Eyes Implanted With Different Multifocal Intraocular Lenses.

Purpose: To investigate potential differences in predictability, efficacy, and safety of corneal excimer laser to correct residual myopia, hyperopia, and astigmatism in eyes previously implanted with multifocal intraocular lenses using distinct optical surfaces and platforms for multifocality.

Methods: This prospective comparative study included 37 eyes submitted to laser in situ keratomileusis correction for residual errors after implantation of either an apodized diffractive-refractive (Restor) or a full-diffractive (Tecnis) multifocal intraocular lens. Data analysis included investigation of predictability, efficacy, and safety of excimer laser surgery to correct residual errors.

Low dose corticosteroid in association with methotrexate for therapy of ocular sarcoidosis: report of a case.

Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Ocular involvement can be the initial manifestation, occurring by itself, or it can be associated with other systemic signs of sarcoidosis. A 31 years-old caucasian female presented a 10-day history of decreased vision and pain in OS.

Pachymetry-guided intrastromal air injection ("pachy-bubble") for deep anterior lamellar keratoplasty: results of the first 110 cases.

Purpose: To report intraoperative and 1-year postoperative results of the pachy-bubble technique for deep anterior lamellar keratoplasty (DALK).

Methods: This prospective interventional case series included 110 eyes of 107 patients with anterior corneal pathology who underwent DALK, including 78 with keratoconus. Outcome measures included the rate of bubble formation, rate of completing DALK, bubble types, complications, and visual and keratometric parameters.

Ophthalmologic findings in hepatitis C patients treated with pegylated interferon α-2b and ribavirin.

Purpose: To identify the effect of pegylated interferon ƒ¿-2b and ribavirin treatment in the ocular fundus examination, visual acuity, and visual field.

Methods: Prospective observational study was performed at the Hepatology Clinic of Sao Jose Regional Hospital and at the Vitreoretinal Department at the Sadalla Amin Ghanem Eye Hospital in patients with chronic hepatitis C before and during treatment with pegylated interferon ƒ¿-2b together with ribavirin.

Results: Six (37.

Tacrolimus for the treatment of subepithelial infiltrates resistant to topical steroids after adenoviral keratoconjunctivitis.

Purpose: To describe the use of topical 0.03% tacrolimus in patients with symptomatic corneal subepithelial infiltrates (SEIs) secondary to adenoviral keratoconjunctivitis (AK) that were resistant to tapering of corticosteroid eye drops.

Methods: This was a prospective, nonrandomized, noncomparative interventional case series that included consecutive patients treated with tacrolimus for resistant SEIs after AK.

Topographic, corneal wavefront, and refractive outcomes 2 years after collagen crosslinking for progressive keratoconus.

Purpose: The aim was to report the corneal higher-order aberrations (HOA), the topographic metrics, and the visual and refractive outcomes 2 years after performing collagen crosslinking (CXL) for progressive keratoconus. The correlation among corneal HOAs, topographic metrics, and visual acuity changes was also investigated.

Methods: This is a prospective case series involving 42 eyes from 32 patients with progressive keratoconus treated with CXL.