175 results match your criteria: "SSM Health Cardinal Glennon Children's Hospital.[Affiliation]"

Forecasting Pediatric Trauma Volumes: Insights From a Retrospective Study Using Machine Learning.

J Surg Res

December 2024

Department of Pediatric Surgery, SSM Health Cardinal Glennon Children's Hospital, St. Louis, Missouri; Department of Pediatric Surgery, St. Louis University, St. Louis, Missouri.

Introduction: Rising pediatric firearm-related fatalities in the United States strain Trauma Centers. Predicting trauma volume could improve resource management and preparedness, particularly if daily forecasts are achievable. The aim of the study is to evaluate various machine learning models' accuracy on monthly, weekly, and daily data.

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Background And Objectives: A wholesale recommendation against use of live virus vaccines in patients treated with any medication classified as an immunosuppressant has been based on global theoretical concerns rather than clinical outcomes for specific drugs.

Methods: A retrospective search of electronic medical records identified patients seen by the Allergy and/or Dermatology services between 2017 and 2023 at a pediatric tertiary center who received a live attenuated vaccine during the 6 week interval prior to the first prescription for methotrexate or dupilumab until 6 weeks after the last prescription for either medication. Individual charts of identified patients were manually reviewed for evidence of adverse events.

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Article Synopsis
  • Patients with congenital heart disease (CHD) have a significantly increased risk of both ischemic and hemorrhagic strokes, with pooled hazard ratios showing they are over three times more likely to experience strokes compared to non-CHD patients.
  • A systematic review analyzed data from eleven studies involving over 5 million participants to assess stroke risks associated with CHD and found higher risks particularly in Europe and among adults rather than children.
  • The study suggests a need for more targeted research to address identified regional and data gaps, which could improve clinical approaches to managing stroke risk in CHD patients.
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Oscillatory Blood Pressure Values in Newborn Infants: Observational Data Over Gestational Ages.

Neonatology

November 2024

Division of Neonatal-Perinatal Medicine, Department of Pediatrics, Saint Louis University School of Medicine, St. Louis, Missouri, USA.

Introduction: Normative blood pressure (BP) values on preterm infants exist but are based on small cohorts of infants. Utilizing electronic medical records (EMR), we can explore earlier gestational ages (GA) and follow their progression to 40 weeks corrected gestational age (CGA).

Methods: A retrospective cohort study of infants within the SSM Health System from July 1, 2013 through June 30, 2023.

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Background: The increased accessibility and utilization of molecular testing including next-generation sequencing (NGS) has impacted the practice of pediatric pathology, with diagnostic, prognostic, and therapeutic implications for our patients. This survey is the first to describe the utilization of molecular testing in the routine practice of pediatric pathology for the care of children with known or suspected solid tumors.

Procedure: The Society for Pediatric Pathology Practice Committee distributed a survey to our membership asking 25 questions about training, practice setting, molecular ordering practices, and barriers to testing.

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Article Synopsis
  • A unique medical case involved a 15-year-old girl who had a cyst near her diaphragm and a possible hernia, even though she showed no symptoms at first.
  • After surgery, she experienced severe stomach pain and they discovered that her stomach had moved through a hole in her diaphragm.
  • To fix it, they put her stomach back where it belongs, and she fully recovered two weeks later; the doctors learned they should check for such holes more carefully in the future.
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Review of Low Titer Group O Whole Blood (LTOWB) Transfusion in Initial Resuscitation of Pediatric Trauma Patients: Assessing Potential Benefits.

J Pediatr Surg

September 2024

Department of Pediatric Surgery, SSM Health Cardinal Glennon Children's Hospital, 1465 S. Grand Blvd. St. Louis, MO 63104, USA; Department of Pediatric Surgery, Saint Louis University School of Medicine, 1402 S Grand Blvd, St. Louis, MO 63104, USA. Electronic address:

Background: Hemorrhagic shock secondary to trauma is a leading cause of pediatric mortality in the United States. Timely intervention is crucial to prevent many of these deaths. Children and adults exhibit distinct responses to trauma due to varying blood volume ratios and injury patterns.

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Objective: Health literacy is the ability to find, understand, and use information and services to inform health-related decisions and actions. Inadequate health literacy is associated with health disparities, poor health outcomes, and increased emergency department (ED) visits and hospitalizations. Children with medical complexity (CMC) have high rates of acute health care utilization.

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Characterizing Pediatric Patients at Risk for Violence-Related Injuries at a Trauma Center in the Midwest United States.

Hosp Top

August 2024

Department of Trauma Surgery, Saint Louis University School of Medicie, SSM Health Saint Louis University Hospital, SSM Health Cardinal Glennon Children's Hospital, Saint Louis, MO, USA.

Introduction: Hospital-based violence intervention programs (HVIPs) have emerged nationwide to help address the societal and economic costs of violence. Little literature exists regarding selecting those patients most likely to benefit from intensive case management. The study aims to describe the pediatric patient population presenting at a Level 1 ACS trauma center with a chief complaint of violent trauma and identify the characteristics of patients most at risk.

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Objective: To evaluate the association between enteral sodium supplementation on growth and hypertension (HTN) in preterm infants.

Study Design: A retrospective cohort study of infants born between 22-32 weeks and weighing 450-1500 grams (N = 821). Enteral sodium supplementation amounts, systolic blood pressures (SBP), weight gain, and other infant and maternal risk factors for HTN were electronically extracted.

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Objectives: Clinical settings are increasingly focused on addressing patients' social needs, thus medical education must prepare future clinicians for this task. Critical consciousness, an awareness that puts health within a broader social, historical, and cultural context, could help shape students' understanding of patient social needs. Our paper explores how experiential learning through participation in a social care intervention deepened students' critical consciousness, or their understanding of the systems and structures that make it difficult for patients to meet their basic needs.

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Article Synopsis
  • - The study evaluated the Person-Centered Care in Fetal Care Centers (PCC-FCC) Scale by gathering feedback from 247 participants who received care at a U.S. Fetal Care Center between 2017 and 2021, using online questionnaires that included both quantitative and qualitative data.
  • - Findings indicated that most participants perceived high levels of person-centered care, especially in care coordination, respect, and education; however, 8% had low scores, and nearly 38% provided negative feedback mainly related to setting expectations, maternal health preparation, and psychosocial support.
  • - The results highlighted the need for improvements in certain areas of care and emphasized the importance of studying diverse patient populations in future research to address insurance
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Timely identification of fetal conditions enables comprehensive evaluation, counseling, postnatal planning, and prenatal treatments. This study assessed the existing evidence on how social determinants of health (SDOH) influence diagnosis timing of fetal conditions appropriate for care in fetal care centers (FCCs). Eligible studies were conducted in the U.

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Systemic inflammation enhances metastatic growth in a syngeneic neuroblastoma mouse model.

Pediatr Surg Int

July 2024

Department of Pediatric Surgery, Kyoto Prefectural University of Medicine, 465 Kajii Cho, Kawaramachi Hirokoji, Kamigyo Ku, Kyoto, 602-8566, Japan.

Article Synopsis
  • The study explores how different surgical approaches affect metastatic growth in a mouse model of neuroblastoma, particularly after total tumor resection.
  • Mice underwent either partial resection, subcutaneous sponge implantation, or were simply observed, with results showing that sponge implantation led to increased lymph node and lung metastases compared to the other groups.
  • Higher levels of C-reactive protein and interleukin-6 were found in the sponge group, indicating that systemic inflammation may play a role in promoting metastatic growth.
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Tiny patients, huge impact: a call to action.

Front Public Health

July 2024

Division of Critical Care Medicine, Department of Pediatrics, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, United States.

The continuation of high-quality care is under threat for the over 70 million children in the United States. Inequities between Medicaid and Medicare payments and the current procedural-based reimbursement model have resulted in the undervaluing of pediatric medical care and lack of prioritization of children's health by institutions. The number of pediatricians, including pediatric subspecialists, and pediatric healthcare centers are declining due to mounting financial obstacles and this crucial healthcare supply is no longer able to keep up with demand.

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Ileocolic intussusception is a consideration in young pediatric patients with acute abdominal pain. Meckel's diverticulum is the most common pathologic lead point for intussusception in children and the appendix acting as the lead point is rare. In addition, management guidelines for recurrent ileocolic intussusception (RICI) are lacking.

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Improving Access to Autism Evaluation: A Coordinated Developmental-Behavioral Pediatrics and Pediatric Neurology Diagnostic Pathway.

Mo Med

June 2024

Division of Developmental-Behavioral Pediatrics, Department of Pediatrics, SSM Health Cardinal Glennon Children's Hospital, Saint Louis University School of Medicine, St. Louis, Missouri.

A shortage of board-certified developmental-behavioral pediatricians generates a bottleneck for children and families who seek autism diagnostic services. Wait time for autism evaluation commonly exceeds a year. To improve access, clinicians developed a coordinated Developmental-Behavioral Pediatrics and Pediatric Neurology autism diagnostic pathway.

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Objectives: To determine the patient-level factors associated with performing daily delirium screening in PICUs with established delirium screening practices.

Design: A secondary analysis of 2019-2020 prospective data from the baseline phase of the PICU Up! pilot stepped-wedge multicenter trial (NCT03860168).

Setting: Six PICUs in the United States.

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Purpose: Arthrogryposis multiplex congenita (AMC) consists of more than 400 conditions involving severe joint contractures of at least two or more body regions. Management of clubfoot in patients with AMC is notoriously challenging, with a higher likelihood of recurrence than idiopathic clubfoot, which can be treated using the Ponseti technique to avoid or delay more invasive procedures. The purpose of this study is to determine the utility of multiple serial casting as a treatment of clubfoot in AMC using Pirani scores as an objective measure of deformity.

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This case report presents a 13-year-old patient with a lung nodule identified on a chest radiograph in the emergency department during an evaluation of knee and side pain after a fall. The patient had nosebleeds, family history of hereditary hemorrhagic telangiectasia (HHT) and after chest computed tomography with angiography, the nodule was defined as a single pulmonary arteriovenous malformation (PAVM). Neither parent nor patient had been evaluated for HHT, an autosomal dominant disease, despite the family history.

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Background: Prevalence and risk of poor psychological outcomes following rhabdomyosarcoma (RMS) are not well-established.

Methods: Participants in this cross-sectional, case-control study (n = 713 survivors, 42.5% female; mean [SD] age, 30.

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