Evaluation of p53 nuclear accumulation in low- and high-grade (WHO/ISUP classification) transitional papillary carcinomas of the bladder for tumor recurrence and progression.

Objectives: To evaluate the association of p53 nuclear accumulation with recurrence and progression in transitional cell carcinomas of the bladder and to examine the distribution of p53 in low-grade and high-grade transitional cell carcinomas according to the World Health Organization/International Society of Urological Pathology classification.

Patients And Methods: Nuclear accumulations of p53 were examined in a total of 99 patients with transitional cell carcinoma between May 1995 and October 1999. The mean age was 64 years.

The value of serum zinc, copper, ceruloplasmin levels in patients with gastrointestinal tract cancers.

Background/aims: Gastrointestinal cancers are frequent diseases of particular importance for surgeons with regard to their management and follow-up. Neoplastic diseases activate antioxidant defense systems. As a result, concentrations of redoxal enzymes and their co-factor elements appear to change.

Primary breast lymphoma cytologic diagnosis.

Primary non-Hodgkin lymphoma of the breast is a rare pathology, and bilateral involvement is exceptional. We report a case of bilateral primary non-Hodgkin lymphoma of the breast in a 40-year-old woman. Predominantly atypical lymphocytes and rare plasma cells were found in the microscopic evaluation of the fine-needle aspiration biopsy of the right and left breasts.

Intussusception in adults: an unusual and challenging condition for surgeons.

Background And Aims: Intestinal intussusception in adults is a rare entity and there is an ongoing controversy regarding the optimal management of this problem. The purpose of this study was to determine the causes and management of intussusception in adults.

Patients And Methods: A retrospective review of patients more than 18 years of age with a diagnosis of intestinal intussusception between January 1996 and December 2003 was conducted.

A case report of the unusual presence of hydatid disease in the pancreas and breast.

Context: Hydatid cyst disease can occur in all viscera and soft tissues although the liver and the lungs are the most commonly involved organs. Pancreatic and breast involvement with the disease are extremely rare and the presence of this disease in these organs without any other organ involvement has not been previously reported.

Case Report: We present herein a patient with isolated pancreatic cyst hydatid treated successfully with complete cyst excision.

Adjuvant chemotherapy in a unique population of patients with gastric cancer undergoing surgery.

Background/aims: Total gastrectomy with D2 dissection theoretically removes the gross primary tumor with its potential route of dissemination, that is locoregional lymph nodes. Complementary therapy for the control of systemic microscopic disease should be taken into consideration in patients whom surgery with curative intent was performed.

Methodology: Twenty-eight patients with moderately differentiated, locally advanced gastric carcinoma underwent total gastrectomy with D2 lymph node dissection.

Two-day induction with thymoglobulin in kidney transplantation: risks and benefits.

Introduction: The aim of this study was to develop an induction protocol to reduce allograft rejection with fewer posttransplant infections and malignancies.

Methods: In this prospective randomized study, a T- and B-cell depletion protocol, consisting of IV thymoglobulin (ATG 5 mg/kg/d) plus methylprednisolone (500 mg/d) plus azathiopurine (2 mg/kg/d), was on days 0 and 1 after renal transplantation. CyA was introduced at day 3.

Mirizzi's syndrome must be ruled out in the differential diagnosis of any patients with obstructive jaundice.

Background/aims: Mirizzi syndrome is a rare benign complication of long-standing cholelithiasis and neither diagnostic modality nor clinical feature has a 100% sensitivity and specificity. The objective of our study was to call attention to the importance of this rare syndrome with its miscellaneous treatments.

Methodology: Between January 1992 and June 1997, a total of 8 (4 females and 4 males) patients, who were operated and diagnosed as Mirizzi syndrome, were retrospectively evaluated.