Acute colchicine intoxication in a child: a case report.

Colchicine poisoning is an uncommon, but potentially life-threatening, toxicologic emergency. The clinical features associated with overdose and the options for treatment are discussed. Colchicine poisoning typically shows 3 phases: initially, gastrointestinal symptoms predominate; in the second phase, multiorgan failure may occur, possibly leading to death.

Bone age and probable aetiological causes in primary nocturnal enuresis.

Aim: To investigate probable aetiological risk factors and to identify whether there are any differences in bone age between normal children and children with primary nocturnal enuresis (PNE).

Methods: Ninety children with primary nocturnal enuresis and 40 healthy children were included in the study. Enrolment began in January 2001, and continued through July 2002.

Nomogram of the fetal gastric size development in normal pregnancy.

Objective: To construct an ultrasonographic nomogram of the fetal gastric size with gestational age in normal singleton pregnancy.

Patients And Methods: Out of 17 000 outpatient pregnant women who were admitted to our hospital, a total of 250 fetal measurements were randomly collected from routine ultrasonographic examinations performed in women with normal singleton pregnancies between 13 and 39 weeks of gestation without medical or obstetric complications. None of the fetuses had detectable fetal malformations.

Moyamoya disease and Down syndrome.

Moyamoya disease is an obstruction of the internal carotids and of the afferent and efferent channels of Willis polygon, which causes a collateral circulation, responsible for the typical angiographic image of a "puff of smoke" (Moyamoya, in Japanese). Its etiology is unknown, and it might be congenital or acquired. The clinical features are cerebral ischemia, recurrent transient ischaemic attacks, sensorimotor paralysis, convulsions and migraine-like headaches.

True hermaphroditism with characteristics of Klinefelter's syndrome: a rare presentation.

True hermaphroditism, a very rare cause of intersex, is usually diagnosed during the newborn period in the course of evaluating ambiguous genitalia. As an exception we report an unusual case of a 14.5 year-old boy with phenotypically near-normal male genitalia and bilaterally descended gonads, who was seen for evaluation of gynecomastia and hematuria.

The relation of increased uterine artery blood flow resistance and impaired trophoblast invasion in pre-eclamptic pregnancies.

Objective: To assess the association between histopathologically confirmed vascular abnormalities developed during pre-eclampsia and abnormal arterial blood flows recorded during Doppler sonographies.

Materials And Methods: From pregnant women who attended our clinic between 01/03/2002 and 01/07/2002, a detailed medical history was obtained and routine biochemical blood tests, fetal ultrasonography and UA Doppler scans were performed. In addition, from pre-eclamptic and normal pregnant women who underwent cesarean sections, placental bed biopsies were taken.

The importance of surgeons' experience on intraobserver and interobserver reliability of classifications used for Perthes disease.

The objective of this study was to evaluate the percentage agreement and intraobserver and interobserver reliability for the Catterall, Salter-Thompson, Herring, and Stulberg classification systems, with special reference to the experience of surgeons. AP and frog-leg radiographs of 10 patients were evaluated by 18 reviewers with three levels of experience on two occasions. Each patient had three sets of radiographs of different stages of disease (initial stage, fragmentation phase, and healed phase).

The effect of femoral lengthening on skeletal muscle: an experimental study in rats.

Background: To investigate the muscular changes occurring during femoral lengthening performed in 42 rats.

Methods: The rats were randomly divided into six groups and different rates of lengthening were utilized and the rats were sacrificed at the end of the distraction. Histopathologic and histomorphometric measurements were done for all specimens.

A clinical and EEG study on idiopathic partial epilepsies with evolution into ESES spectrum disorders.

Purpose: Questioning the presence of any possible prognostic predictors, this study includes a long-term follow-up of clinical and EEG characteristics of 16 patients with idiopathic partial epilepsy (IPE) who subsequently developed epilepsy with electrical status epilepticus during slow sleep (ESES) spectrum disorders.

Methods: Epilepsy, cognitive and behavioral parameters, and waking and non-rapid eye movement (NREM) EEG data were evaluated and scored for initial stage (i.e.

General anesthesia versus epidural and general anesthesia in radical cystectomy.

Introduction: The aim of this study is to compare two different anesthetic techniques in radical cystectomy with regard to blood loss, transfusional requirements, intraoperative complications and the quality of analgesia.

Materials And Methods: 50 patients scheduled for radical cystectomy were randomized to two groups: group GA - general anesthesia, n = 25 and group CEGA - combined epidural and general anesthesia. The patients were monitored and hemodynamic changes, intraoperative bleeding, transfusional requirements, quality of analgesia and postoperative complications were evaluated.

Transuterine migration as a complication of intrauterine contraceptive devices: six case reports.

Objectives: We retrospectively analyzed six cases between 1986 and 2002 that had been operated within our unit with the diagnosis of migration of an intrauterine contraceptive device (IUD). Although an IUD is an effective contraceptive method, the migration of one is a rare but serious complication. The aim of this report is to emphasize the management and therapy of this complication.

Adaptation of functional outcomes of sleep questionnaire (FOSQ) to Turkish population.

Turkish version of functional outcomes of sleep questionnaire (FOSQ.tr) was examined for its psychometric properties in patients with obstructive sleep apnoea hypopnoea syndrome (OSAHS). The FOSQ was translated into Turkish using a forward-backward translation.

The effect of transdermal fentanyl treatment on serum cortisol concentrations in patients with non-cancer pain.

We treated 50 patients with chronic nonmalignant pain using transdermal fentanyl (TDF) 25 microg/hr and concurrently measured pain using a visual analog scale (VAS) and serum cortisol concentration. We determined these outcomes at baseline and on days 30, 60, and 90 of the therapy. The patients also were asked to document any adverse effects.

PER-1 production in a urinary isolate of Providencia rettgeri.

A Providencia rettgeri strain resistant to extended-spectrum cephalosporins and intermediate to aztreonam was isolated from the urine of a patient hospitalized in the urology clinic of SSK Educational Hospital in Ankara. Clavulanic acid restored the activity of extended-spectrum cephalosporins, suggesting that the strain was harboring an extended-spectrum beta-lactamase. Since the PER-1 enzyme is widespread in Turkey, and had been already detected in a related species such as Proteus mirabilis, the Providencia strain was suspected of harboring a PER-1 enzyme, which was indeed detected by PCR.

Evaluation of adding preoperative or postoperative rectal paracetamol to caudal bupivacaine for postoperative analgesia in children.

Background: Our aim was to investigate whether effects of caudal analgesia could be extended by preoperative or postoperative rectal paracetamol administration in children undergoing surgical repair of hypospadias.

Methods: The group consisted of 60 ASA I boys, aged 3-12 years, who were operated for surgical repair of hypospadias. The patients were randomized into three groups: patients in group I received rectal paracetamol (20-25 mg x kg(-1)) just before the operation.

Granulomatous cheilitis resulting from a tuberculide.

Granulomatous cheilitis (GC) is a chronic granulomatous inflammation of the lips of unknown etiology. The possible relationship with tuberculosis has been described although most of the studies excluded infectious agents as potential causes of the granulomatous response. To our knowledge only one case of granulomatous cheilitis resulting from a tuberculide has been reported in the literature but accompanying internal involvement has not been previously described.

[The influence of sarcoidosis on quality of life].

In the follow up of chronic illnesses like sarcoidosis, the psychological and social dimensions are getting more important in addition to the clinical parameters. It is the quality of life (QoL) that brings psychological and social dimensions in to the clinic. In this study we aimed to investigate the QoL of patients suffering from sarcoidosis.

Intraobserver and interobserver reliability of Catterall, Herring, Salter-Thompson and Stulberg classification systems in Perthes disease.

Objective: To assess the percentage agreement and intraobserver and interobserver reliability among Catterall, Salter-Thompson, Herring and Stulberg classification systems with special reference to the stage of treatment.

Methods: Anteroposterior and frog-leg radiographs of 10 patients were evaluated by 18 reviewers on two occasions. Each patient had three sets of radiographs of different stages of disease: before treatment, 6-12 months after the initiation of treatment and at least 5 years after the treatment.

A prospective, randomized, controlled trial of primary wound closure after lateral internal sphincterotomy.

Background: Much of the lateral internal sphincterotomy (LIS) complications is related to LIS incision. In this study, incisions sutured primarily or left to secondary healing after open LIS procedure are compared regarding the wound healing and complications associated with wounds.

Methods: Planning a prospective, randomized clinical study, 39 patients were separated into two groups.

Primary vaginal leiomyosarcoma in pregnancy.

Background: Primary vaginal sarcoma constitutes about 2% of all malignant vaginal lesions, with leiomyosarcoma being the most common in adult women. To our knowledge, this is the first case of vaginal leiomyosarcoma occurring during pregnancy.

Case: A 21-year-old woman, at 39 weeks of gestation, presented with a pedunculated vaginal mass.

Adult type granulosa cell tumor causing precocious pseudopuberty in a 6 year-old girl.

Malignant ovarian tumors are responsible for 2-3% of all cases of precocious pseudopuberty (PP) in girls. The most common forms of ovarian tumors presenting as PP are the granulosa cell tumors (GCT). The clinical and pathological features of granulosa cell tumors that occur frequently in young girls, so-called juvenile granulosa cell tumors (JGCT), differ histologically from those occurring in adults.

Chemotherapy induced transverse leukonychia in children.

Transverse white nail banding can be inherited or caused by various diseases and medications, including cancer chemotherapeutic agents, retinoids, tetracyclines, antimalarials, sulfonamides, pilocarpine, cortisone and zidovudine. Neither a specific drug nor classes of cancer chemotherapeutics were associated more frequently than the other with acquired transverse leukonychia in patients with cancer. Here we report transverse leukonychia in four children with cancer receiving different chemotherapeutic agents.

Osteoporosis after renal transplantation.

This study was performed to determine risk factors associated with osteoporosis that develops after renal transplantation. Sixty-five kidney graft recipients were included in this study. They were divided into four groups according to the time since transplantation: Group 1 (< 1 year; n = 26), group 2 (1-3 years; n = 16), group 3 (3-5 years; n = 12) and group 4 (> 5 years; n = 11).

The role of intra-peritoneal honey administration in preventing post-operative peritoneal adhesions.

Objective(s): The accelerative effect of honey in the wound healing process is known. This effect is related to its specific physical properties of hygroscopicity, hypertonicity, lower pH and complex chemical composition. Because peritoneal healing is a kind of wound healing process we hypothesised that post-operative peritoneal adhesions (PPA) may be reduced with intra-peritoneal honey administration.