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Evaluation of clinical efficacy and safety of once daily topical administration of 1% oxiconazole cream and lotion in dermatophytosis : an open label, non comparative multicentre study.

Indian J Dermatol Venereol Leprol

October 2012

LTM Medical College & LTM General Hospital, Sion, Mumbai, Madras Medical College & Government General Hospital, Madras, SSG Medical College and General Hospital, Baroda, Glaxo & Wellcome India, India.

The clinical efficacy and safety of once daily topical administration of 1% oxiconazole cream and lotion was assessed in an open label, non comparative trial in tinea cruris, tinea corporis and tinea pedis patients. In treated patients, severity scores of erythema, pruritus, scaling, vesicles, papules and burning showed a progressive fall over a period of 4 weeks at all the study centres. With lotion, mean percentage improvement of symptoms varied from 35% (week 1) to 87.

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