Revolutionizing dairy waste: emerging solutions in conjunction with microbial engineering.

The dairy industry is grappling with significant challenges in managing effluent due to environmental concerns and stringent regulatory demands, necessitating innovative solutions. The paper investigates how microbial engineering is transforming the treatment of dairy wastewater, offering advanced methods to minimize environmental impact and enhance sustainability. It delves into the current challenges faced by the dairy industry, such as regulatory compliance and the limitations of traditional treatment technologies, and introduces microbial engineering as a promising solution for effluent management.

Unleashing the future: The revolutionary role of machine learning and artificial intelligence in drug discovery.

Drug discovery is a complex and multifaceted process aimed at identifying new therapeutic compounds with the potential to treat various diseases. Traditional methods of drug discovery are often time-consuming, expensive, and characterized by low success rates. Because of this, there is an urgent need to improve the drug development process using new technologies.

Unlocking the role of herbal cosmeceutical in anti-ageing and skin ageing associated diseases.

The process of skin ageing is a natural biological phenomenon characterised by the emergence of wrinkles, age spots, sagging skin, and dryness over time. The increasing significance of skin in physical attractiveness has heightened skincare concerns. Anti-ageing cosmetics play a pivotal role in nurturing the skin, enhancing its quality, and promoting overall health.

Exploring the diverse performance of nickel and cobalt spinel ferrite nanoparticles in hazardous pollutant removal and gas sensing performance.

A simple sol-gel combustion process was employed for the creation of MFeO (M=Ni, Co) nanoparticles. The synthesized nanoparticles, acting as both photocatalysts and gas sensors, were analyzed using various analytical techniques. MFeO (M=Ni, Co) material improved the degradation of methylene blue (MB) under UV-light irradiation, serving as an enhanced electron transport medium.

Visible-Light-Driven Regioselective Decarboxylative Acylation of -Methyl-3-phenylquinoxalin-2(1)-one by Dual Palladium-Photoredox Catalysis Through C-H Activation.

We report herein an efficient visible-light-promoted approach for the regioselective decarboxylative C-H acylation of -methyl-3-phenylquinoxalin-2(1)-ones using α-oxo-2-phenylacetic acids dual palladium-photoredox catalysis. The reactions were carried out at room temperature in the presence of 24 W blue LEDs. The established protocol tolerated a wide range of functional groups and enabled the synthesis of several acylated -methyl-3-phenylquinoxalin-2(1)-ones in good to excellent yields.

Optimizing the effect of ultrasonication and germination on antinutrients and antioxidants of kodo () and little () millets.

Kodo () and little () millet grains were utilized to minimize their antinutrient content (phytate and tannin) and maximize their antioxidant activity (DPPH) by studying the effect of ultrasonication time, germination time and temperature using central composite rotatable design. Results revealed the optimum conditions for producing ultrasonicated and germinated kodo and little millet flour of the highest antioxidant activity and lowest antinutrient content (phytate and tannin) by using 30 min for ultrasonication, 72 h for germination at 40 °C. Further, a second order model was developed to describe and predict the effect of process variables on antioxidant activity and antinutrient contents.

Hyper-parameter tuned deep learning approach for effective human monkeypox disease detection.

Human monkeypox is a very unusual virus that can devastate society. Early identification and diagnosis are essential to treat and manage an illness effectively. Human monkeypox disease detection using deep learning models has attracted increasing attention recently.

Characterization of Phietavirus Henu 2 in the virome of individuals with acute gastroenteritis.

There is a growing interest in phages as potential biotechnological tools in human health owing to the antibacterial activity of these viruses. In this study, we characterized a new member (named PhiV_005_BRA/2016) of the recently identified phage species Phietavirus Henu 2. PhiV_005_BRA/2016 was detected through metagenomic analysis of stool samples of individuals with acute gastroenteritis.

Secondary Metabolite Profiling, Antioxidant, Antidiabetic and Neuroprotective Activity of (Night Scented-Jasmine): Use of In Vitro and In Silico Approach in Determining the Potential Bioactive Compound.

This study aims to describe the therapeutic potential of leaf extracts against diabetes and neurological disorders via the targeting of α-amylase and acetylcholinesterase (AChE) activities, followed by computational molecular docking studies to establish a strong rationale behind the α-amylase and AChE inhibitory potential of leaves-derived secondary metabolites. In our study, the antioxidant activity of the sequentially extracted leaves extract was also investigated, in which the methanolic fraction exhibited the strongest antioxidant potential against DPPH (IC 39.12 ± 0.

Artificial Intelligence-Based Ensemble Learning Model for Prediction of Hepatitis C Disease.

Machine learning algorithms are excellent techniques to develop prediction models to enhance response and efficiency in the health sector. It is the greatest approach to avoid the spread of hepatitis C, especially injecting drugs, is to avoid these behaviors. Treatments for hepatitis C can cure most patients within 8 to 12 weeks, so being tested is critical.

Non-contact breathing rate monitoring in newborns: A review.

The neonatal period - the first 4 weeks of life - is the most critical time for a child's survival. Breathing rate is a vital indicator of the health condition and requires continuous monitoring in case of sickness or preterm birth. Breathing movements can be counted by contact and non-contact methods.

Multi-criterion Intelligent Decision Support system for COVID-19.

COVID-19 is a buzz word nowadays. The deadly virus that started in China has spread worldwide. The fundamental principle is "if the disease can travel faster information has to travel even faster".

Impact of the transverse direction on the many-body tunneling dynamics in a two-dimensional bosonic Josephson junction.

Tunneling in a many-body system appears as one of the novel implications of quantum physics, in which particles move in space under an otherwise classically-forbidden potential barrier. Here, we theoretically describe the quantum dynamics of the tunneling phenomenon of a few intricate bosonic clouds in a closed system of a two-dimensional symmetric double-well potential. We examine how the inclusion of the transverse direction, orthogonal to the junction of the double-well, can intervene in the tunneling dynamics of bosonic clouds.

Aldehydes: magnificent acyl equivalents for direct acylation.

From the viewpoint of meeting the current green chemistry challenges in chemical synthesis, there is a need to disseminate how the cocktail of acylation and activation can play a pivotal role in affording bioactive acylated products comprising substituted ketone motifs in fewer reaction steps, with higher atom-economy and improved selectivity. In recent years, a significant number of articles employing the title compounds "aldehydes" as magnificent acylation surrogates which are less toxic and widely applicable have been published. This review sheds light on the compounds use for selective acylation of arene, heteroarene and alkyl (sp3, sp2 and sp) C-H bonds by proficient utilization of the C-H activation strategy.

Possible activation of NRF2 by Vitamin E/Curcumin against altered thyroid hormone induced oxidative stress via NFĸB/AKT/mTOR/KEAP1 signalling in rat heart.

Oxidative stress is implicated in both hypo- and hyper-thyroid conditions. In the present study an attempt has been made to elucidate possible interaction between vitamin E or/and curcumin (two established antioxidants) with active portion (redox signaling intervening region) of nuclear factor erythroid 2-related factor 2 (NRF2) as a mechanism to alleviate oxidative stress in rat heart under altered thyroid states. Fifty Wistar strain rats were divided into two clusters (Cluster A: hypothyroidism; Cluster B: hyperthyroidism).