Disruptive multiple cell death pathways of bisphenol-A.

Endocrine-disrupting chemicals (EDCs) significantly contribute to health issues by interfering with hormonal functions. Bisphenol A (BPA), a prominent EDC, is extensively utilized as a monomer and plasticizer in producing polycarbonate plastic and epoxy resins, making it one of the highest-demanded chemicals in commercial use. This is the major component used in plastic products, including bottles, containers, storage items, and food serving ware.

Exploring Perceptions and Treatment-Seeking Behaviors for Viral Hepatitis Among the Ethnic Irula Tribe in Tamil Nadu, India: A Qualitative Study on Health Disparities.

Objectives: Qualitative research was undertaken to determine the perceptions and treatment-seeking behaviors of the Irula tribal populations in Tamil Nadu, India, and to explore the depth, diversity, and complexity of viral hepatitis.

Methods: An in-depth interview (IDI) was conducted among the eligible respondents. A purposive sampling technique was used to obtain the study subjects.

Effects of and Pranayama on Cardio Respiratory Function in Post-COVID Patients: A Randomised Controlled Study.

Background: The COVID-19 pandemic has led to a range of long-term health issues in recovered patients, collectively known as "post-COVID syndrome."

Purpose: This study aimed to investigate the effects of combined pranayama techniques, specifically and , on pulmonary function and heart rate variability in post-COVID patients.

Methods: A randomised controlled trial was conducted with 90 post-COVID patients (aged 19-40).

Advances in Migraine Treatment: A Comprehensive Clinical Review.

Migraine is a neurological disease that, while not inherently causing "chronic headaches," can evolve into a chronic condition over time including major symptoms such as nausea, and light, sound, and allodynia, particularly in cases of frequent episodic migraine or due to factors such as medication overuse or inadequate management. This condition's complex pathophysiology makes treatment difficult. Genetics, trigeminovascular system activation, and cortical spreading depression are involved.

IoT-based prediction model for aquaponic fish pond water quality using multiscale feature fusion with convolutional autoencoder and GRU networks.

The Internet of Things (IoT)-based smart solutions have been developed to predict water quality and they are becoming an increasingly important means of providing efficient solutions through communication technologies. IoT systems are used for enabling connection between various devices based on the ability to gather and collect information. Furthermore, IoT systems are designed to address the environment and the automation industry.

Management of female para-urethral cyst with dyspareunia: a case report.

Background: The diagnosis and management of female genital conditions (Rodriguez et al. in Clin Anat 34(1):103-107, 2020. https://doi.

Spatiotemporal generation of alternating disparate pH domains audible sound controlled opposing enzymatic reactions.

Intracellular spatiotemporal chemical heterogeneities with controlled properties are essential for life. However, creating these heterogeneities artificially is challenging. In this study, we used both acid- and base-producing enzymatic reactions simultaneously and demonstrated that the execution of these reactions in the presence of audible sound can effectively create spatiotemporally ordered pH domains in a solution.

Bibliometric Analysis of the Role of Artificial Intelligence in Detecting Maxillofacial Fractures.

Facial bone fractures are a common occurrence in trauma cases, particularly in India where road traffic accidents contribute significantly. Over the past few years, artificial intelligence (AI) has become a potent instrument to help medical professionals diagnose and treat facial fractures. This study aims to perform a bibliometric analysis, that is, a quantitative and qualitative analysis, of publications focusing on the role of AI in detecting facial bone fractures.

The Prevalence of Alveolar Ridge Defects According to Seibert's Classification: A Cross-Sectional Study.

Background and objective Alveolar ridge defects in partially edentulous patients present significant challenges in prosthodontic treatment planning. Seibert's classification system provides a structured approach to categorizing these defects based on the buccolingual and apico-coronal dimensions of the ridge. Accurate classification is crucial for determining appropriate treatment strategies for implant placement, fixed prosthesis, or tissue augmentation.

Alkaloid-rich fraction from Luffa cylindrica Linn fruit enhances memory and mitigates oxidative stress in hippocampus of ozone-exposed sprague Dawley rat via LCMS and network pharmacology approach.

Luffa cylindrica (L.), is a medicinal plant aimed to investigate the efficacy of the alkaloid-rich fraction (ARF) extracted from L. cylindrica.

Issues and Limitations on the Road to Fair and Inclusive AI Solutions for Biomedical Challenges.

Objective: In this paper, we explore the correlation between performance reporting and the development of inclusive AI solutions for biomedical problems. Our study examines the critical aspects of bias and noise in the context of medical decision support, aiming to provide actionable solutions. Contributions: A key contribution of our work is the recognition that measurement processes introduce noise and bias arising from human data interpretation and selection.

Synergistic effects of fly ash and graphene oxide composites at high temperatures and prediction using ANN and RSM approach.

Fly ash (FA) is a consequence of burning coal and is widely used in construction because of its pozzolanic qualities, which increase the strength and longevity of materials. Graphene oxide (GO) is a functionalized version of graphene with low electrical conductivity, high mechanical strength, and a large surface area. By examining the behavior of fly ash and GO composites at high temperatures, new materials with improved mechanical and functional qualities that are appropriate for a range of industrial uses can be created.

Electrospun nanofibers of collagen and chitosan for tissue engineering and drug delivery applications: A review.

Tissue engineering plays a vital role in the medical field that addresses the repair, regeneration, and replacement of damaged tissues or organs. The development of drug-eluting electrospun nanofiber composed of biological macromolecules plays a key role in providing localized drug delivery and structural support. This review examines the recent development and impact of electrospun nanofibers in the field of tissue engineering and explores their potential applications.

Hybrid optimization enabled DenseNet for autism spectrum disorders using MRI image.

Autism spectrum disorder (ASD) is the neuro-developmental disorder caused by various changes in the brain. It affects the life conditions with social interaction and communication. Most of the previous researches used the various techniques for the early detection to reduce the ASD, but it had been occurred several complications such as, time expenses, and low accessibility for diagnosis.

A novel hollow-core antiresonant fiber-based biosensor for blood component detection in the THz regime.

This article proposes a novel biosensor based on a five-semi-circular cladding tube hollow core antiresonant fiber (HC-ARF) with a frequency range of 0.5-2.8 THz, using Zeonex as the background material.

Reducing noble metal dependence: oxygen evolution reaction with a Ru-minimized BiRuO@MOF-801 composite.

Developing efficient and noble metal-minimized electrocatalysts for the oxygen evolution reactions (OER) is critical for energy conversion reactions. Here we present Ru-minimized BiRuO@MOF-801 that synergistically combines the high catalytic activity of the bimetallic oxide with the unique structural and hydrophilic properties of the Zr-MOF. The composite achieves superior OER performance with a low overpotential of 307 mV at 50 mA cm and a Tafel slope of 99.

Evaluating oral health status in elderly Irula tribes of Tamil Nadu by using the Geriatric Oral Health Assessment Index.

Introduction: Oral diseases are a significant global health issue, with over 3.5 billion cases worldwide. Caries and periodontitis are primary contributors to tooth loss, which not only incurs significant rehabilitation costs but also profoundly affects overall well-being.

Comparison of single-point insulin sensitivity estimator (SPISE) index and cognitive performance in vitamin B-deficient young adults: An analytical cross-sectional study.

Background: Vitamin B is an essential micronutrient, aids in synthesis of neurotransmitters, and vital for cognitive function. In the current younger population with more of electronic gadgets and scientific world seems to slow down critical thinking and impairs the trick of comprehensive subjective learning. Vitamin B deficiency has been linked to insulin-resistant state and future cardiovascular risk.

A protocol to study the effect of targeted parental education intervention to identify early childhood development disorder - multisite interventional study.

Background: In India, approximately 3.5 million children are affected by Developmental Delay (DD), often stemming from preterm births. These delays contribute to neurological and motor development delays, placing a significant financial burden on families.

Exploring the separation, characterization and antioxidant activity of proteins and peptides from selected seagrasses in Palk Bay region of Tamil Nadu in India.

In this study, five seagrass species Halodule uninervis, Thalassia hemprichii, Enhalus acoroides, Cymodocea serrulata, and Syringodium isoetifolium collected from the Mandapam coastal region of Rameswaram (Palk Bay region), Tamil Nadu, India, were selected to identify the antioxidant-rich proteins/peptides. The primary objective was to identify the proteins/peptides present in these seagrass filtrates extracted by using four different pH-based buffer extracts and to assess their antioxidant activity. Among the various buffer extracts, 0.

Fluorescent N-Doped Carbon Dots as a Biocompatible Sensor for Thiophanate-Methyl Detection.

An eco-friendly nitrogen-passivated carbon dot (N-CDs)-based fluorescent sensor was designed for the selective and sensitive detection of thiophanate-methyl, a widely applied fungicide in agriculture. The synthesized N-CDs exhibited robust fluorescence and remarkable photostability, which contributed to the sensor's performance. Notably, the sensor achieved a detection limit as low as 4.

Marine-Derived Compound Targeting mTOR and FGFR-2: A Promising Strategy for Breast, Lung, and Colorectal Cancer Therapy.

Introduction: The marine habitat is a plentiful source of diverse, active compounds that are extensively utilised for their medicinal properties. Pharmaceutical trends have currently changed towards utilising a diverse range of goods derived from the marine environment.

Method: This study aimed to examine the inhibitory effects of bioactive chemicals derived from marine algae and bacteria.

Antimicrobial Potentials of Haliclona fibulata Derived Compounds for Combatting Drug-Resistant Bacterial Infections in Zebrafish Model.

The rising threat of antimicrobial resistance among pathogens highlights the critical need for novel antimicrobial agents. This study explores the potential of natural products by investigating n-hexane extracts from the marine sponge Haliclona fibulata (HF) for their antibacterial efficacy. The well diffusion method of HF extract showed significant antibacterial activity against Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus with inhibition zones of 20 ± 0.