75 results match your criteria: "SRM (Sri Ramaswamy Memorial) Medical College Hospital & Research Centre[Affiliation]"

Article Synopsis
  • Benign prostatic hyperplasia (BPH) is the leading cause of lower urinary tract symptoms, and the study explores how vitamin D's anti-inflammatory properties might help alleviate these symptoms.
  • The research involved men aged 45 to 80 with urinary issues, categorizing them based on their prostate-specific antigen (PSA) levels to assess the link between vitamin D levels and prostate health.
  • Results indicated that PSA levels rise with age, particularly in men over 60, and a negative correlation between PSA and vitamin D levels was found in men aged 60 to 69.
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Follicular lymphoma (FL) is a gradually progressing type of B-cell non-Hodgkin lymphoma (NHL), distinguished by its characteristic follicular pattern of growth and a typically indolent clinical course. It is identified by the abnormal growth of B-cells in the lymph nodes. We report a case of a 45-year-old female who came up with complaints of heavy menstrual bleeding and easy fatiguability.

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Infective endocarditis (IE) primarily affects the endocardium of the heart valves. One of the common neurological complications of IE is the embolization of endocardial vegetation, which can obstruct the cerebral arteries. We describe the case of a 47-year-old male patient who developed neurological symptoms as a complication of IE.

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Introduction Breast cancer is a significant health concern in India, representing a large portion of all cancers affecting women and ranking as one of the most common cancers overall. Reliable diagnostic tools are essential for accurately predicting malignancy and reducing the need for unnecessary biopsies. A Breast Imaging Reporting and Database System (BI-RADS) 3 designation suggests a low likelihood of cancer, indicating that findings are likely benign.

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Article Synopsis
  • * A total of 150 laboratory workers participated, using a questionnaire to assess demographics, safety practices, and perceptions of workplace safety, with statistical analysis performed via Microsoft Excel and SPSS.
  • * Results show poor safety habits: 62% of participants do not wash their hands before wearing gloves, and 20% consume food at work; perceptions about workplace disturbances are significantly influenced by factors like age and job responsibilities.
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A Paradigm Shift in Renal Cell Carcinoma: Recognizing Hypoglycaemia as a Significant Paraneoplastic Syndrome.

Cureus

November 2024

Department of General Medicine, Sri Ramaswamy Memorial (SRM) Medical College Hospital and Research Centre, SRM Institute of Science and Technology, Chengalpattu, IND.

Recurrent hypoglycaemia is a rare paraneoplastic syndrome associated with several cancers, including renal cell carcinoma (RCC). Here we present a curious case of a patient with type 2 diabetes mellitus (T2DM) who had numerous hospitalisations due to recurrent hypoglycaemia. A well-defined lesion at the lower pole of the right kidney and bilateral pyelonephritis were found during imaging investigations.

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Introduction The abdomen comprises several layers that enhance its strength and flexibility, extending from the superficial to the deep layers of the anterior abdominal wall. Among these, the rectus sheath serves as a fibromuscular compartment essential for structural integrity, providing mechanical support and safeguarding the underlying tissues and organs. This study evaluates two midline closure techniques employed after midline laparotomy surgery to determine which technique offers superior strength and mechanical support.

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Immunoglobulin A vasculitis (IgAV; initially known as Henoch-Schönlein purpura) is a form of vasculitis involving the small blood vessels of the gastrointestinal tract, skin, joints, and kidney, presenting as a multisystem disorder. A 21-year-old gentleman presented with joint pain, skin rash, abdominal pain, and proteinuria. Biopsies performed from the skin and kidney were both consistent with IgA deposition.

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Article Synopsis
  • Majocchi's granuloma is a dermatological condition where dermatophytes invade deeper skin layers, often triggered by trauma or excessive use of topical corticosteroids.
  • A 57-year-old man experienced itchy skin lesions on his right ankle after using over-the-counter steroids, leading to the diagnosis of Majocchi's granuloma evidenced by clinical and histopathological findings.
  • The patient was treated with oral terbinafine and topical luliconazole, resulting in resolution of lesions within three weeks, though he was advised to continue treatment for two months.
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Introduction Psoriasis involves rapid cell growth and abnormal differentiation of skin cells. Dysregulation of apoptosis has been proposed in the pathogenesis of psoriasis. The role of Bcl-2 as an anti-apoptotic protein in pathogenesis has not been studied in detail in these cases.

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Facial nerve palsy (FNP) may arise from multiple etiological reasons, including anatomical anomalies, circulatory complications, and infectious agents. This case series underscores the importance of a comprehensive diagnostic approach to identify the precise etiology, including structural abnormalities, vascular anomalies, or infectious illnesses. Here, we present three distinct occurrences of FNP, emphasizing the varied diagnostic difficulties and therapeutic strategies.

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Analyzing the Anatomical Characteristics of the Facial Artery Branches: A Human Cadaveric Study.

Cureus

October 2024

Department of Oral and Maxillofacial Surgery, Sri Ramaswamy Memorial (SRM) Kattankulathur Dental College and Hospital, Sri Ramaswamy Memorial Institute of Science and Technology (SRMIST), Chengalpattu, IND.

Article Synopsis
  • The study focuses on the facial artery, a key blood supply source for the head and neck, aiming to map its branches and measure their dimensions in relation to face and neck landmarks.
  • Conducted on 60 hemifaces from 30 male cadavers, the research used statistical methods to analyze the diameter and length of the facial artery branches, noting significant values for the superior labial, inferior labial, lateral nasal, angular, and submental branches.
  • The results revealed no major side-to-side differences in most branches, except for the submental artery, which showed a notable variation, providing valuable anatomical insights for surgical planning, particularly for the Indian population.
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Systemic lupus erythematosus (SLE) is an intricate autoimmune disease characterized by its impact on various organ systems, presenting with a wide range of clinical manifestations such as hematologic, neuropsychiatric, mucocutaneous, serosal, musculoskeletal, immunologic, cardiac, pleuropulmonary, and renal symptoms. Although its etiology is primarily autoimmune, various triggers, such as pregnancy, certain drugs, and infections, can result in "flares" with frequent relapses. Although more common in females, SLE is not uncommon in males, with a significant proportion experiencing a high disease burden.

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Background The metabolic score for insulin resistance (METS-IR) is a neoteric score for assessing insulin resistance that has been used as a non-insulin-based, objectively measured method. It is an easily accessible tool that can be used on a large scale to detect insulin resistance in a community. Methods We conducted a retrospective cohort study to explore the utility of this score in identifying metabolic risk in those individuals attending a master health checkup in a tertiary care setting.

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Article Synopsis
  • Crohn's disease (CD) significantly affects patients' quality of life, and this review assesses the effectiveness and safety of upadacitinib, a JAK inhibitor, in treating it.
  • The analysis included seven studies with 1,481 patients, and results showed upadacitinib outperforms placebo in achieving clinical remission and reducing inflammation quickly, often within five to six days.
  • While the treatment has a generally acceptable safety profile, with risks like infections and laboratory abnormalities, it presents as a promising option for managing moderate to severe CD, particularly for those who have not responded to other therapies.
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Dengue and Typhoid: A Duet of Choreoathetosis.

Cureus

September 2024

General Medicine, Sri Ramaswamy Memorial (SRM) Medical College Hospital and Research Centre, SRM Institute of Science and Technology (SRMIST), Chengalpattu, IND.

Article Synopsis
  • A 16-year-old male with fever presented typical symptoms of paroxysmal dystonic choreoathetosis after an acute illness, but initially showed no involuntary movements.
  • * While hospitalizing, he developed involuntary movements in both upper and lower limbs, as well as his face, suggesting a rare condition.
  • * Co-infection with dengue and typhoid, which is becoming more common, complicates treatment and management for physicians.
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Background: Non-carious cervical lesions (NCCLs) present themselves as smooth saucer lesions with variable height and depth. Treatment of choice for these lesions should be aimed at conservative management by restoring the teeth. The present study aims to evaluate the micro-tensile bond strength in NCCLs after various surface pre-treatments.

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Article Synopsis
  • Bronchiolitis is a common respiratory illness in children under two, primarily caused by respiratory syncytial virus, leading to respiratory distress and wheezing.
  • The study focused on children with their first wheezing episode, excluding those with pre-existing health conditions, to assess clinical profiles, risks, severity, and outcomes using statistical analysis.
  • Results showed that younger children faced more severe bronchiolitis, with higher prevalence in males, and initial symptoms often included cough and respiratory distress, particularly in those with irritability.
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Aim: The study aimed to evaluate the effects of alpha hydroxy acids and chelating agents on dentin conditioning for the release of growth factors.

Methods: The agents used for dentin conditioning included 17% ethylenediaminetetraacetic acid (EDTA), 10% glycolic acid (GA), 10% citric acid (CA), and 5% maleic acid (MA). Forty horizontally sectioned (SV1) human dentine slices were conditioned for 5 and 10 minutes so that the growth factor liberation reached quantifiable levels.

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Gambling, which was previously restricted to physical casinos and card rooms, has become readily accessible through internet platforms and virtual card games as a result of recently developed technological advances. The increase in the prevalence of pathological gambling (PG) disorder has been attributed to the extensive availability of online gambling platforms and the covert advertising that is associated with them. In this case, we examine an individual with a PG disorder who is intrigued by online gambling.

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Xanthogranulomatous pyelonephritis (XGPN) is a chronic granulomatous inflammatory condition that affects the kidney and can often be hard to diagnose preoperatively due to its varying clinical presentations. We present here a rare case of a 36-year-old man with focal XGPN with preoperative CT imaging showing a large heterogenous lesion (computer tomography Hounsfield unit (CT HU) + 20) of size ~ 8.6 x 8.

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Article Synopsis
  • * A case report discusses a patient with type 2 diabetes who had unusual symptoms that made it hard to diagnose, with initial treatments failing.
  • * The use of advanced microbiological methods helped quickly identify the pathogen, leading to effective treatment and stressing the importance of considering melioidosis in severe infection cases, especially for patients with preexisting conditions.
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Article Synopsis
  • The study investigates how marital status influences the quality of life (QoL) of women, comparing married and single women living near a tertiary care hospital.
  • It involved 200 women (100 married and 100 single), using the WHO-QOL-BREF questionnaire to assess various QoL aspects including physical, psychological, social, and environmental factors.
  • Results indicated that married women had higher family incomes and better social QoL scores, while single women were generally younger and lived in nuclear families; however, there were no significant differences in physical, psychological, or environmental QoL domains between the two groups.
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Breast masses presenting as fungating growths usually represent advanced malignancy. One remarkable exception is a benign phyllodes tumour. These tumours of stromal origin often exhibit rapid growth, resulting in pressure necrosis at the summit of the tumor causing fungation.

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Two Interesting Cases of Thyroid Gland Tuberculosis.

Cureus

September 2024

Department of Radiodiagnosis, SRM Medical College Hospital and Research Centre, Sri Ramaswamy Memorial Institute of Science and Technology (SRMIST), Chengalpattu, IND.

Tuberculosis involving the thyroid gland is an exceptionally rare condition with varied clinical presentations, often leading to diagnostic challenges. We report two cases: a 9-year-old male with necrotic tuberculous cervical lymphadenopathy secondarily involving the thyroid gland, and a 40-year-old male with disseminated tuberculosis affecting multiple organ systems, including the thyroid gland. Both cases presented with swelling over the neck region and were evaluated using ultrasonography and contrast-enhanced computed tomography (CECT), which revealed characteristic imaging findings of thyroid involvement.

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