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Utility of BoneXpert in assessing bone age and bone health in Indian children and youth with type 1 diabetes mellitus.

Bone

October 2023

Department of Paediatric growth and Endocrinology, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, India; Interdisciplinary School of Health Sciences, Savitribai Phule University, Pune, India.

Article Synopsis
  • BoneXpert (BX) is useful for evaluating bone age (BA) and metacarpal index (MCI) in Indian children and youth with type-1 diabetes (T1D), but its application in this group had not been previously studied.
  • A study of 1,272 T1D subjects revealed that BX can accurately assess BA, with minimal errors compared to established methods, and MCI showed a significant correlation with bone density measurements.
  • Findings indicated that over 50% of subjects exhibited decreased MCI, highlighting the importance of monitoring factors like height and vitamin D levels, as well as the negative impact of HbA1c and T1D duration on bone health.
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