Significant Implications of Gene Sequence Variations and Its Protein Expression in Bladder Cancer.

Apolipoprotein A1 () is a potential biomarker because of its variable concentration in different types of cancers. The current study is the first of its kind to evaluate the association between the genotypes of -75 G/A and +83 C/T in tandem with the protein expression in urine samples to find out the risk and potential relationship for differentially expressed urinary proteins and genotypes. The study included 108 cases of bladder tumors and 150 healthy controls that were frequency matched to cases with respect to age, sex, and smoking status.

Association of -75G/A and +83C/T polymorphic variation with acute coronary syndrome patients in Kashmir (India).

Acute coronary syndrome (ACS) comes under the ambit of cardiovascular disease.APOA-1 gene plays a vital role in lipid metabolism and has been observed to have plausible role in ACS. This cross sectional case-control study was conducted to evaluate association between 1-75G/A(rs1799837), +83C/T (rs5069) genotypes and risk for ACS.