EVALUATION OF ETORPHINE-MEDETOMIDINE-MIDAZOLAMAZAPERONE FOR IMMOBILIZATION IN CAPTIVE PRONGHORN ().

Etorphine based immobilization protocols are reported to be effective in pronghorn; however, information on cardiorespiratory effects is limited. The objective of this study was to evaluate the efficacy and cardiopulmonary effects of etorphine, medetomidine, midazolam, and azaperone for immobilization in captive pronghorn. Additionally, the effects of endotracheal intubation and manual ventilation on cardiopulmonary variables were assessed.

International society of sports nutrition position stand: β-hydroxy-β-methylbutyrate (HMB).

Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on an analysis of the literature regarding the effects of β-Hydroxy-β-Methylbutyrate (HMB). The following 12 points have been approved by the Research Committee of the Society: 1. HMB is a metabolite of the amino acid leucine that is naturally produced in both humans and other animals.

Covered Stent Correction for Sinus Venosus Atrial Septal Defects, an Emerging Alternative to Surgical Repair: Results of an International Registry.

Background: Covered stent correction for a sinus venosus atrial septal defect (SVASD) was first performed in 2009. This innovative approach was initially viewed as experimental and was reserved for highly selected patients with unusual anatomic variants. In 2016, increasing numbers of procedures began to be performed, and in several centers, it is now offered as a standard of care option alongside surgical repair.

Cultural and religious structures influencing the use of maternal health services in Nigeria: a focused ethnographic research.

Background: Cultural and religious structures encompass a set pattern of values, beliefs, systems and practices that define a community's behaviour and identity. These structures influence women's health-seeking behaviour and access to maternal health services, predisposing women to preventable maternal health complications. However, most maternal health policies have focused on biomedical strategies, with limited attention to women's cultural challenges around childbirth.

Measuring personality in Libyan Arabs: validating the big five aspect scale with 10 factors domain.

Research has developed the Big-Five Aspect Scale (BFAS), supporting a five-domain model that includes 10 related aspects. In Arabic societies, there is currently a lack of validation evidence for a scale with these 10 aspects. Thus, this study develops and examines the psychometric properties of the short version of the BFAS (BFAS-SV) within Libyan Arab adults.

Efficacy and acceptability of pharmacological interventions for tardive dyskinesia in people with schizophrenia or mood disorders: a systematic review and network meta-analysis.

Tardive Dyskinesia (TD) can occur in people exposed to dopamine receptor antagonists (DRAs). Its clinical management remains challenging. We conducted a systematic review/random-effects network meta-analysis (NMA) searching PubMed/MEDLINE/PsycINFO/ClinicalTrials.

Tracing nitrogen use efficiency of diverse Canadian spring wheat cultivars.

Decades of wheat breeding have provided growers with numerous high-yielding options, but it is unknown if these yield improvements are likewise characterized with improved nitrogen use efficiency (NUE). Fertilizer nitrogen (N) is an ever-increasing expense, so improving NUE by reducing the requirement for N fertilizer without risking yield and quality is necessary. The goal of our research is to identify cultivars and associated traits that may improve NUE while maintaining productivity.

Does land use change decline the regional ecosystem health maintenance? Case study in subtropical coastal region, Fuzhou, China.

Regional environmental management aims to maintain or improve regional ecosystem health (REH) and prevent its degradation over time. In the context of rapid urbanization and global sustainability over the last two decades, has land use change resulted in a deterioration of REH? By using the improved REH framework model as Pressure-Vigor-Organization-Resilience-Service (P-VOR-S), this paper proposed Regional Ecosystem Health Maintenance (REHM) as a dynamic quantitative indicator of REH, and detected REHM as well as its response to land use change in the coastal city of Fuzhou, China during 2003-2018. The results showed that: (1) During 2003-2018, the average REH gradually decreased in spite of the 62.

Temporal kinetics of serum amyloid A (SAA) concentration and identification of SAA isoforms in blood and synovial fluid of horses with experimentally induced septic arthritis, non-septic synovitis, and systemic inflammation.

Prompt diagnosis of equine septic arthritis is crucial for successful treatment. Serum amyloid A (SAA) has been suggested as a reliable biomarker. However, we previously found that synovial fluid SAA increases in nonaffected joints of horses with septic arthritis.

Advancing thyroid care: An accurate trustworthy diagnostics system with interpretable AI and hybrid machine learning techniques.

The worldwide prevalence of thyroid disease is on the rise, representing a chronic condition that significantly impacts global mortality rates. Machine learning (ML) approaches have demonstrated potential superiority in mitigating the occurrence of this disease by facilitating early detection and treatment. However, there is a growing demand among stakeholders and patients for reliable and credible explanations of the generated predictions in sensitive medical domains.

A Parallel Process of Staff-Family Distress in Long-Term Care: A Challenge to Collaboration.

Introduction: Supporting persons living with advanced dementia in long-term care (LTC) homes requires strong collaborative partnerships between staff, family members, and residents. Yet, relational tensions-such as differing expectations around care decisions-can inhibit the implementation of collaborative partnerships at this critical point in the trajectory of care.

Objective: This study aims to explore the emotional experiences of families and staff during shared decision-making processes for individuals with advanced dementia in LTC.

MugenNet: A Novel Combined Convolution Neural Network and Transformer Network with Application in Colonic Polyp Image Segmentation.

Accurate polyp image segmentation is of great significance, because it can help in the detection of polyps. Convolutional neural network (CNN) is a common automatic segmentation method, but its main disadvantage is the long training time. Transformer is another method that can be adapted to the automatic segmentation method by employing a self-attention mechanism, which essentially assigns different importance weights to each piece of information, thus achieving high computational efficiency during segmentation.

Feline Diabetes Is Associated with Deficits in Markers of Insulin Signaling in Peripheral Tissues.

Like humans, cats have a strong relationship between decreasing insulin sensitivity and the development of diabetes with obesity. However, the underlying molecular mechanisms of impaired insulin secretion and signaling in cats remain largely unknown. A total of 54 client-owned nondiabetic lean ( = 15), overweight ( = 15), and diabetic ( = 24) cats were included in the study.

Effect of Treatment Methods on Material Properties and Performance of Sawdust-Concrete and Sawdust-Polymer Composites.

The circular economic approach in polymer composite research has gained acceptance for offering low-cost, high-performance solutions. Sawdust-derived composites have drawn interest as alternatives in concrete and composite fabrication, addressing housing shortages and resource depletion. Sawdust concrete (SDC) and sawdust polymer composites (SDPC) are key areas under investigation, with SDC additionally aiding in carbon reduction in building materials.

A Comparative Review of Eugenol and Citral Anticandidal Mechanisms: Partners in Crimes Against Fungi.

is an emerging multidrug-resistant opportunistic pathogen that causes candidiasis, superficial infections on the mucosa, nails or skin, and life-threatening candidemia in deep tissue when disseminated through the bloodstream. Recently, there has been a sharp rise in resistant strains, posing a considerable clinical challenge for the treatment of candidiasis. There has been a resurged interest in the pharmacological properties of essential oils and their active components, for example, monoterpenes with alcohol (-OH) and aldehyde (-CHO) groups.

Ambulatory pediatric adenotonsillectomy.

Purpose: This Continuing Professional Development module aims to help the general anesthesiologist recognize common pitfalls in ambulatory pediatric adenotonsillectomy and perform appropriate risk stratification, analgesic management, and disposition planning.

Principal Findings: Pediatric adenotonsillectomy is a widely performed procedure. An updated approach to preoperative risk assessment of commonly associated comorbidities allows the practitioner to anticipate and plan for adverse events.

Fostering Adherence to Evidence-Based Care in the Management of Musculoskeletal Shoulder Pain: A Mixed Methods Study.

Objective: The objective was to identify the priorities of individuals with musculoskeletal shoulder pain and their health care providers (HCPs) that are perceived to foster multi-stakeholder adherence to evidence-based recommendations.

Methods: The study used a mixed methods design, informed by concept mapping. Patients with shoulder pain (ie, ≥6 weeks) and HCPs involved in their care (recruited via social media, email, etc.

Health Care Providers' Well-being Indicators are Associated With Their Intention to Leave Their Positions: A Cross-Sectional Study From Saskatchewan, Canada.

This study aimed to measure the intention to leave and well-being indicators (ie, job satisfaction, burnout, moral distress, risk of depression, and resilience) of health care providers (HCPs) in Saskatchewan, Canada and to explore the association between their intention to leave and well-being indicators and other demographic factors, including gender. A cross-sectional study was conducted among registered nurses (RNs), physicians, and respiratory therapists (RTs) in Saskatchewan between December 2021 and April 2022. An online survey inquired about intentions to leave current positions, well-being indicators, and demographics of HCPs.

Radioimmunotherapy combating biofilm-associated infection .

Background: Addressing prosthetic joint infections poses a significant challenge within orthopedic surgery, marked by elevated morbidity and mortality rates. The presence of biofilms and infections attributed to () further complicates the scenario.

Objective: To investigate the potential of radioimmunotherapy as an innovative intervention to tackle biofilm-associated infections.

Acute sport-related concussion alters cardiac contribution to cerebral oxygenation during repeated squat stands.

Assessment of cerebral oxygenation during repeated squat stands following an acute sport-related concussion (SRC) has the potential to identify physiological changes following SRC. All varsity university athletes completed a pre-season assessment and 53 were followed up within 5-days of suffering an SRC. Of the 53 participants, 29 had continuous beat-to-beat blood pressure (BP; sampled at 200 hz) collected by finger photoplethysmography, and 53 had right prefrontal cortex oxygenation collected by near-infrared spectroscopy (NIRS; sampled at 10 hz).

Identification of key signaling pathways and novel computational drug target for oral cancer, metabolic disorders and periodontal disease.

Aim: Due to conventional endocrinological methods, there is presently no shared work available, and no therapeutic options have been demonstrated in oral cancer (OC) and periodontal disease (PD), type 2 diabetes (T2D), and obese patients. The aim of this study is to determine the similar molecular pathways and potential therapeutic targets in PD, OC, T2D, and obesity that may be used to anticipate the progression of the disease.

Methods: Four Gene Expression Omnibus (GEO) microarray datasets (GSE29221, GSE15773, GSE16134, and GSE13601) are used for finding differentially expressed genes (DEGs) for T2D, obese, and PD patients with OC in order to explore comparable pathways and therapeutic medications.

Design of composite chitosan/algae/zeolite by freeze- or air-drying: A comparative adsorbent analysis for optimized removal of brilliant green dye.

A bio-composite material was developed that contains chitosan, food-grade algae, and zeolite for the removal of brilliant green (BG) dye. The synthesized bio-composite was dried via two different methods (air-drying; AD, and freeze-drying; FD). The physicochemical characterization of air-dried chitosan-algae-zeolite (Cs-Alg-Zl-AD) and freeze-dried chitosan-algae-zeolite (Cs-Alg-Zl-FD) were investigated by spectroscopy (FTIR, SEM-EDX, and XPS), diffraction (XRD), surface charge via pH, specific surface area (SSA) and elemental analyses.

Multicenter Validation of the Ocular Myasthenia Gravis Rating Scale Questionnaire.

Background And Objectives: Ocular myasthenia gravis (OMG) causes disabling ocular symptoms of ptosis and diplopia, but a validated disease-specific patient-reported outcome measure (PROM) has not been reported. We sought to validate a novel PROM for OMG, OMG Rating Scale Questionnaire (OMGRate-q), as a measure of visual functioning to support patient-centered care.

Methods: This was a prospective study of patients aged 18 years and older with OMG receiving care at 3 medical centers (January 2022-October 2023).