Mathematical modeling of infectious diseases and the impact of vaccination strategies.

Mathematical modeling plays a crucial role in understanding and combating infectious diseases, offering predictive insights into disease spread and the impact of vaccination strategies. This paper explored the significance of mathematical modeling in epidemic control efforts, focusing on the interplay between vaccination strategies, disease transmission rates, and population immunity. To facilitate meaningful comparisons of vaccination strategies, we maintained a consistent framework by fixing the vaccination capacity to vary from 10 to 100% of the total population.

Effects of autism spectrum disorder on parents labour market: Productivity loss and policy evaluation in Kazakhstan.

Kazakhstan has witnessed a significant increase in the number of Autism Spectrum Disorder cases due to the implementation of mechanisms for early detection. However, despite these efforts, accessing quality services and effective interventions for individuals with Autism Spectrum Disorder remains challenging. While the government has implemented various policies to address the impact of Autism Spectrum Disorder on the labour market, especially for those with disabilities, the effectiveness of these policies needs to be evaluated.

Design and Evaluation of a Low-Power Wide-Area Network (LPWAN)-Based Emergency Response System for Individuals with Special Needs in Smart Buildings.

The Internet of Things (IoT) is a growing network of interconnected devices used in transportation, finance, public services, healthcare, smart cities, surveillance, and agriculture. IoT devices are increasingly integrated into mobile assets like trains, cars, and airplanes. Among the IoT components, wearable sensors are expected to reach three billion by 2050, becoming more common in smart environments like buildings, campuses, and healthcare facilities.

KZ-BD: Dataset of Kazakhstan banknotes with annotations.

The field of deep learning is rapidly advancing and impacting various industries, including banking. However, there are still challenges when it comes to accurately identifying the denomination of currencies, especially when dealing with issues like variation within the same class of currency and inconsistent lighting conditions. One notable problem is the lack of available data for Kazakhstan's currency.

High school physics teachers' pedagogical discontentment: The effect of curriculum improvement and professional development programs.

Pedagogical discontentment refers to the feeling of dissatisfaction or frustration that teachers experience with the current state of their teaching. The purpose of this study is to explore high school physics teachers' pedagogical discontentment within the Kazakhstani context. A survey was administered to 126 physics teachers from urban and suburban areas.

WRN loss accelerates abnormal adipocyte metabolism in Werner syndrome.

Background: Metabolic dysfunction is one of the main symptoms of Werner syndrome (WS); however, the underlying mechanisms remain unclear. Here, we report that loss of WRN accelerates adipogenesis at an early stage both in vitro (stem cells) and in vivo (zebrafish). Moreover, WRN depletion causes a transient upregulation of late-stage of adipocyte-specific genes at an early stage.

WRN promotes bone development and growth by unwinding SHOX-G-quadruplexes via its helicase activity in Werner Syndrome.

Werner Syndrome (WS) is an autosomal recessive disorder characterized by premature aging due to mutations of the WRN gene. A classical sign in WS patients is short stature, but the underlying mechanisms are not well understood. Here we report that WRN is indispensable for chondrogenesis, which is the engine driving the elongation of bones and determines height.

Excess medical comorbidity and mortality across the lifespan in schizophrenia.: A nationwide Danish register study.

Introduction: People with severe mental illness have greater risk of un-detected and inadequately treated medical disorders, adding up to the risk of premature death. This study investigated how chronic medical comorbidity evolved across the lifespan in schizophrenia and the associated impact on mortality.

Method: A register-based retrospective nested case-control study was conducted, identifying incident cases of cardiovascular disease (CVD), chronic obstructive pulmonary disease (COPD), cancer and diabetes, as well as mortality due to these diseases, across the lifespan in schizophrenia.

Induced dielectric-force-effect by 50 Hz strong electric field on living tissue.

The main objective of this paper is to study on the fields, resultant forces, and the dielectric substances in biologic tissues. Additionally, to unveil the possible mechanism which affects on major biological activities were examined. In the scientific literature, there are many studies conducted with low frequency Electromagnetic Fields (MFs), Static Magnetic Fields (SMFs), and Pulsed Electromagnetic Fields (PEMFs).