Electron microscopic evaluation of the effect of therapeutic silicone hydrogel lenses on the limbal area.

Purpose: To investigate the effects of high-permeability silicone hydrogel contact lenses used for therapeutic purposes on limbal cells, inflammation, and neovascularization.

Methods: Bullous keratopathy was induced by injection of 0.05% benzalkonium chloride into the anterior chamber of 20 anesthetized rabbit eyes.