5 results match your criteria: "SB Goztepe Training and Research Hospital[Affiliation]"
Evaluation of oxidative stress via protein expression of glutathione S-transferase and cytochrome p450 (CYP450) ısoenzymes in psoriasis vulgaris patients treated with methotrexate.
Cutan Ocul Toxicol
June 2018
c Department of Biology , Kırıkkale University, Kırıkkale , Turkey.
Introduction: Oxidative stress is the imbalance between oxidant-antioxidant systems and may play a major role in the psoriasis pathogenesis. Cytochrome (CYP) is a family of enzymes that are responsible for the metabolism of various endogenous and exogenous substances such as drug metabolism. Most importantly, the antioxidant system is the glutathione S-transferases (GST), which decrease oxidative stress by reducing oxidative products.
View Article and Find Full Text PDFFirst-line treatment in senior adults with metastatic castration-resistant prostate cancer: A prospective international registry.
Urol Oncol
May 2016
Department of Urology, Hacettepe University, Ankara, Turkey.
Article Synopsis
- * Data from 333 patients showed that taxane therapy significantly improved overall and progression-free survival compared to nontaxane therapy, even among frail patients, and was generally well tolerated with specific side effects.
- * The findings indicate that taxane therapy may be more beneficial for older adults with mCRPC than other treatments, and treatment decisions should not solely rely on a patient's age.
Oral mucosal involvement and petechial lesions: a SDRIFE case with unusual findings.
Cutan Ocul Toxicol
December 2016
f Department of Pathology , SB Goztepe Training and Research Hospital, Istanbul Medeniyet University, Istanbul , Turkey.
Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) is a type IV hypersensitivity reaction characterized by a symmetrical erythematous rash in the gluteal and intertriginous areas. SDRIFE was previously considered to be the same presentation as Baboon Syndrome, however, has been suggested to be a different entity in the recent publications. The lesions are generally maculopapular and there is no mucosal involvement.
View Article and Find Full Text PDFA comparative study of histopathological findings in skin biopsies from patients with psoriasis before and after treatment with acitretin, methotrexate and phototherapy.
Cutan Ocul Toxicol
September 2016
b Department of Dermatology , Istanbul Medeniyet University, School of Medicine, SB Goztepe Training and Research Hospital, Istanbul , Turkey , and.
Introduction: Psoriasis is a chronic and inflammatory skin disease. Few studies in the literature evaluate the responses to the treatment histopathologically.
Objectives: In this study, we evaluated and compared skin biopsies taken from patients with psoriasis before and after phototherapy and therapy with acitretin and methotrexate.
Chiari malformation type III and results of surgery: a clinical study: report of eight surgically treated cases and review of the literature.
Pediatr Neurosurg
May 2009
Department of Neurosurgery, SB Goztepe Training and Research Hospital, Istanbul, Turkey.
Background: The characteristics of Chiari malformation type III and its treatment are evaluated in this study. Radiological and surgical findings were correlated and the benefits of the therapy are discussed.
Methods: Eight patients (6 males, 2 females) with Chiari malformation type III were studied.