A comprehensive study on impact of noise exposure on roadside school childrens' cognitive performance.

An uncontrolled vehicular population escalates distraction and affects mental wellness due to ambient noise, profoundly affecting the academic landscape. This study investigates the significant influence of ambient noise on schoolchildren's learning, attention, and cognition, underscoring the critical challenges and potential limitations it poses to their academic progress. Cognitive assessments were conducted under prevailing noise and controlled conditions.

Thiazepine-Based Hybrids as Promising Anti-Colon Cancer Agents: Design, Synthesis, Computational and In Vitro Screening.

Novel thiazepine-based hybrids (9 a-d) were designed and synthesized to create lead molecules with exceptional anti-colon cancer efficacy. Analytical methods, including IR, NMR, and HR-MS, characterized the synthesized compounds. The in vitro colorectal study was carried out to compare the biological activity of newly developed compounds with the computational data.

Automated diagnosis of atherosclerosis using multi-layer ensemble models and bio-inspired optimization in intravascular ultrasound imaging.

Atherosclerosis causes heart disease by forming plaques in arterial walls. IVUS imaging provides a high-resolution cross-sectional view of coronary arteries and plaque morphology. Healthcare professionals diagnose and quantify atherosclerosis physically or using VH-IVUS software.

Monolayer AlC: Mechanical, Thermoelectric, and Promising Sensing Properties for Environmentally Toxic/Nontoxic Oxygen-Containing Gases.

This work investigated the possibility of a monolayer AlC nanosheet as an optimistic sensor for ecologically poisonous/harmless oxygen-containing gases (OCGs), which includes CO, CO, and HO, implementing nonequilibrium Green's function (NEGF) and first-principles computations. The sensing properties of a pure AlC monolayer were explored in this study, including their mechanical and thermoelectric properties. The pristine AlC has a maximum mobility in the armchair direction for the hole carrier of 62797.

Aerosols and black carbon variability using OMI and MERRA-2 and their relationship to near-surface air temperature.

An extinction of incoming solar radiation is taking place by absorption and scattering by dust, water droplets, and gaseous molecules. Such phenomena are responsible for altering meteorological variables. In the present study, temporal analysis of the aerosol optical thickness (AOT) and black carbon (BC) surface mass concentration was undertaken using an ozone monitoring instrument (OMI) and modern-era retrospective analysis for research and applications, version 2 (MERRA-2) satellite from the year 2018 to 2022.

Data analytics and modelling in context to determination of moisture susceptibility of reclaimed asphalt foamed bituminous mix.

The presence of water badly affects the moisture susceptibility of the reclaimed asphalt Foamed Bituminous Mix (FBM). The present study is mainly emphasized to assess the moisture susceptibility of reclaimed asphalt FBM, Where RAP is being incorporated as a replacement of fresh aggregates. Moisture susceptibility of the mix is evaluated in terms of tensile strength ratio (TSR) and resilient modulus ratio, subjected to different conditioning procedures namely AASHTO T283, modified IDOT, TG-2 guidelines, and MIST.

Association of road traffic noise exposure and school childrens' cognition: A structural equation model approach.

This study explores the complex relationship between traffic noise and school children's cognition, acknowledging existing empirical inconsistencies and aiming to contribute to a richer understanding of this pivotal issue. Schools adjacent to noisy roads were selected, and outdoor noise levels were measured employing a Kimo dB300 sound level meter, focusing on noise level indices L, L, and L. Subsequent calculations were performed to determine the noise pollution level (L), noise climate (NC), and traffic noise index (TNI), revealing a severe noise exposure when compared to standard guidelines.

Thermal damage analysis in tissue caused by electromagnetic radiation using space-time collocation method.

Over the past half-century, the usage of external heat sources in medical applications has increased substantially. Controlling heat damage is essential for ensuring the efficacy of the treatment. Living tissues are highly non-homogeneous; hence, it is important to take into account the effects of local non-equilibrium on their thermal behavior.

Impact of Interdependent Ca and IP Dynamics On ATP Regulation in A Fibroblast Model.

The vital participation of Ca in human organ functions such as muscular contractions, heartbeat, brain functionality, skeletal activity, etc, motivated the scientists to thoroughly research the mechanisms of calcium (Ca) signalling in distinct human cells. Ca, inositol triphosphate (IP), and adenosine triphosphate (ATP) play important roles in cell signaling and physiological processes. ATP and its derivatives are hypothesized to be important in the pathogenic process that leads to fibrotic illnesses like fibrosis.

A Transparent, Tough and Self-Healable Biopolymeric Composites Hydrogel for Open Wound Management.

Modern healthcare engineering requires a wound dressing solution supported by materials with outstanding features such as high biological compatibility, strong mechanical strength, and higher transparency with effective antibacterial properties. Here, we present a unique hydrogel technology consisting of two negatively charged biopolymers and a positively charged synthetic polymer. The interaction between charged polymers through hydrogen bonds has been created, which are revealed in the simulation by density functional theory and Fourier transform infrared spectra of individual polymers and the hydrogel film.

Computational insight of antioxidant and doxorubicin combination for effective cancer therapy.

Doxorubicin (DOX) is the most effective antineoplastic agent, destroys cancer cells by interrupting cellular function. However, the serious side effects on the heart limits its utility. To curb these unwanted side effects, nutritionist recommend antioxidants use along with DOX while chemotherapy.

Simulation of biochemical dynamics of [Formula: see text] and [Formula: see text] in fibroblast cell.

Calcium dynamics is not only responsible for maintaining the framework and functions of the cell but also plays a role in the dynamics of other biochemical systems in the cell. Phospholipase C-[Formula: see text] l ([Formula: see text]) has a crucial role in the function of fibroblast cells. Experiments have shown that [Formula: see text] and [Formula: see text] have interdependent dynamics in fibroblast cells.

Computational study on 2D three-phase lag bioheat model during cryosurgery using RBF meshfree method.

Biological tissue has a multidimensional and non-homogeneous inner structure by nature. The temperature distribution and freezing front locations in biological tissue are crucial to optimizing the damage to tissue during cryosurgery. There is a need for a good mathematical model and effective simulation techniques to predict the effectiveness of the therapy.

New bis[MoO] and [MoO(O)] compounds: An artificial enzyme with peroxidase activity against o-phenylenediamine and dopamine.

In this study, two binuclear dioxido- and oxidoperoxido molybdenum (VI) complexes, [{MoO}(L)(HO)] 1 and [{MoO(O)}(L)(HO)] 2, were synthesized. Complex 1 was obtained through a 1:2 reaction of ligand I with MoO(acac), while complex 2 was synthesized in situ by reacting MoO with HO in a 1:2 ratio. The structures and characteristics of the complexes were examined employing several techniques such as elemental (CHN) analysis, spectroscopy (FT-IR, UV-Vis, H, and CNMR), and thermal study (TGA).

Structural Distortion of β-Cyclodextrin Plays a Key Role in the pH-dependent Host-Guest Chemistry with Doxorubicin, Evident by the Electrochemical and Molecular Dynamics Approach.

β-Cyclodextrin (β-CD) is the potential drug carrier to deliver antitumor drugs like doxorubicin (DOX). However, the mechanism for the inclusion complex formation is still unclear and needs to be explored. This study investigated the effect of pH on the inclusion of DOX into thiolated β-CD (β-CD-SH) by electrochemical and molecular dynamics (MD) simulation.

G2/M-Phase-Inhibitory Mitochondrial-Depolarizing Re(I)/Ru(II)/Ir(III)-2,2'-Bipyrimidine-Based Heterobimetallic Luminescent Complexes: An Assessment of In Vitro Antiproliferative Activity and Bioimaging for Targeted Therapy toward Human TNBC Cells.

Triple-negative breast cancer (TNBC) is an extremely vicious subtype of human breast cancer having the worst prognosis along with strong invasive and metastatic competency. Hence, it can easily invade into blood vessels, and presently, no targeted therapeutic approach is available to annihilate this type of cancer. Metal complexes have successfully stepped into the anticancer research and are now being applauded due to their anticancer potency after the discovery of cisplatin.

New bis[-{MoO}] complexes with dihydrazone ligands: synthesis, characterization, theoretical investigation and their peroxidase mimicking activity.

Three binuclear dioxidomolybdenum complexes designated as [{MoO}(L)(HO)] 1, [{MoO}(L)(HO)] 2, and [{MoO}(L)(HO)] 3 with dihydrazone ligands, HLI, HLII, and HLIII, have been prepared by the process with ligands and MoO(acac) in a ratio of 1 : 2. Many analytical techniques have been used to describe these complexes, including elemental (CHN) analysis, spectroscopy (FT-IR, UV-vis, H, and CNMR), and TGA analysis. SC-XRD analysis has been employed to study the structures of these complexes 1a, 2a, and 3a revealing the octahedral geometry and the binding of one molybdenum atom to each side of azomethine nitrogen, enolate oxygen, and a phenolic oxygen atom.

Synthesis, characterization, molecular dynamic simulation, and biological assessment of cinnamates linked to imidazole/benzimidazole as a CYP51 inhibitor.

A class of 2-(1-imidazol-1-yl)-1-phenylethyl cinnamates and 2-(1-benzo[]imidazol-1-yl)-1-phenylethyl cinnamates were synthesized, and their synthesis was validated using various spectroscopic techniques like IR, NMR, and Mass spectrometry. In addition, the compounds were assessed for antibacterial against gram-positive and gram-negative strains and antifungal against six different fungal strains. Compounds , , , and exhibited significant activity against all bacterial strains ranging from and compounds , , and exhibited considerable activity against all fungal strains ranging from .

Luminescent 11-{Naphthalen-1-yl}dipyrido[3,2-a:2',3'-c]phenazine-Based Ru(II)/Ir(III)/Re(I) Complexes for HCT-116 Colorectal Cancer Stem Cell Therapy.

Due to a number of unpleasant considerations, marketed drugs have steadily lost their importance in the treatment of cancer. In order to find a viable cancer cell diagnostic agent, we therefore focused on metal complexes that displayed target adequacy, permeability to cancer cells, high standard water solubility, cytoselectivity, and luminescent behavior. In this aspect, luminescent 11-{naphthalen-1-yl} dipyrido [3,2-a:2',3'-c] phenazine based Ru(II)/Ir(III)/Re(I) complexes have been prepared for HCT-116 colorectal cancer stem cell therapy.

Application of multi-criteria decision-making techniques to develop modify-leachate pollution index.

The modify-leachate pollution index (m-LPI) was developed with the help of multi-criteria decision-making (MCDM) technique based on the landfill leachate pollution potential by considering the limitations of traditional methodologies. Across India, twenty major landfill sites (LS) were selected for which m-LPI was assessed. Twenty-five experts' opinions were taken for the determination of nine input criteria weights, such as pH, COD, TDS, Cl, Zn, Pb, Cu, annual rainfall, and landfill age with the help of a questionnaire-based survey.

Hydrothermal carbonization of cow dung with human urine as a solvent for hydrochar: An experimental and kinetic study.

Hydrothermal carbonization (HTC) is the most cost-effective, environmentally friendly, and efficient physicochemical and biochemical process for converting biomass to products with added value. The objective and novelty of this work is to produce and investigate the qualities of hydrochar fuel (as a solid fuel) from cow manure using human urine as a solvent in order to find a suitable replacement for conventional fuel (i.e.

Advancement in concept to develop biomaterials from agricultural waste for tissue engineering and biomedical applications.

Unlabelled: Presently on a global scale, one of the major concerns is to find effective strategies to manage the agricultural waste to protect the environment. One strategy that has been drawing attention among the researchers is the development of biocompatible materials from agricultural waste. This strategy implies successful conversion of agricultural waste products (e.

Study on generalized fuzzy fractional human liver model with Atangana-Baleanu-Caputo fractional derivative.

This study aims to develop a novel fuzzy fractional model for the human liver that incorporates the ABC fractional differentiability, also known as ABC gH-differentiability, based on the generalized Hukuhara derivative. In addition, a novel fuzzy double parametric -homotopy analysis method with a generalized transform and ABC gH-differentiability is used to deal with the fuzzy mathematical model and examine its convergence analysis. The stability of the unique equilibrium point for the fuzzy fractional human liver model and the existence of a unique solution in the proposed model are investigated using the Arzela-Ascoli theorem and Schauder's fixed-point theory.

Exploration of Molecular Structure, DFT Calculations, and Antioxidant Activity of a Hydrazone Derivative.

The hydrazine derivatives are known to possess several biological activities including anticancer, antibacterial and anti-fungal, anticonvulsant, and antioxidant. This communication presents the synthesis, X-ray crystal structure analysis, DFT calculations, cell cytotoxicity, and antioxidant activity of the Schiff base 4,4'-((1E,1'E)-hydrazine-1,2-diylidenebis(ethan-1-yl-1-ylidene))bis(benzene-1,3-diol) (compound ). We have also isolated the side product compound and characterized it using single X-ray crystallography.