Free radical synthesis of succinic anhydride grafted poly(lactic acid) porous templates for sustained drug delivery in the buffer media.

Poly(lactic) (PLA) is a biodegradable material obtained from renewable resources and is recognized as a safe biopolymer by the Food and Drug Administration. PLA expresses excellent mechanical and moldability attributes nonetheless poor elasticity/functionality limits its widespread utilization. One approach to compensate for this is chemical surface modification through free radical grafting with small organic molecules like maleic anhydride (MA).

Effects of Dexpanthenol on Corneal Neovascularization and Inflammation on Rat Model.

Purpose: To evaluate the effect of subconjunctival injection of dexpanthenol on corneal neovascularization and inflammation in rats with induced chemical burns.

Methods: This experimental study included 40 female albino Wistar rats. Chemical burns were induced in the right eye of all rats on the first day, and the left eye was used as a control.

Social media experiences of solo leisure travelers during the travel process: A phenomenological study.

The rise of solo travel has become a significant trend in the leisure sphere; nonetheless, there is limited understanding of how solo travelers utilize social media throughout their travel process. This lack of insight represents a research problem, as it hinders the ability to enhance solo travel experiences through social media engagement. Addressing this gap, this study investigates the specific ways in which solo leisure travelers experience and engage with social media during their journeys.

The appearance of external genital organs and anogenital distance in male fetal cadavers.

This study aimed to determine the normal size of the male external genital organs and anogenital distance in human fetuses during the fetal period through the anatomic morphometric method. The study was performed on 104 spontaneously aborted human male fetuses aged between 10 and 39 weeks of gestation. Fetuses were divided into groups according to gestational weeks, months, and trimesters.

Celiac Disease in Children and YouTube: Do the Videos Contain Accurate Information?

Objective: Celiac disease (CD) is a gluten-associated enteropathy whose incidence has been increasing in recent years. Parents whose children are diagnosed with CD search for information about the disease via the internet. YouTube is one of the most frequently used platforms to access information due to the number of users and ease of access.

Preliminary validation of the virtual bariatric endoscopic simulator.

Background And Aims: Obesity is a global health concern. Bariatric surgery offers reliably effective and durable weight loss and improvements of other comorbid conditions. However, the accessibility of bariatric surgery remains limited.

Angiotensin-Converting Enzyme Insertion/Deletion Gene Polymorphism in Chronic Rhinosinusitis with Nasal Polyps.

Objective: Inflammatory processes play a role in the etiopathogenesis of chronic rhinosinusitis. Many gene polymorphisms have been associated with inflammation. In this study, we aimed to examine the relationship between angiotensin-converting enzyme insertion/deletion gene polymorphism and chronic rhinosinusitis.

Choriocapillaris flow in two different patterns of exudative type 1 macular neovascularization.

Background: To compare the characteristics of type 1 macular neovascularization (MNV) and the surrounding choriocapillaris (CC) perfusion in patients with neovascular age-related macular degeneration (nAMD) versus those with pachychoroid neovasculopathy (PNV) using swept-source optical coherence tomography angiography (SS-OCTA).

Methods: This retrospective study included 64 treatment-naïve eyes (37 nAMD, 27 PNV) with type 1 MNV. SS-OCTA images were analysed to measure MNV area and perimeter, and CC flow deficits (FD) in five concentric rings surrounding the lesion.

Serum NMR Metabolomics in Distinct Subtypes of Hematologic Malignancies.

Hematological malignancies encompass a diverse array of subtypes, contributing to substantial heterogeneity that poses challenges in predicting clinical outcomes. Leveraging the capabilities of nuclear magnetic resonance holds substantial promise in the detection of serum biomarkers and individual metabolic alterations in patients. The study involved the analysis of the sera from patients with acute myeloid leukemia, chronic lymphocytic leukemia, and non-Hodgkin lymphoma to investigate the impacted metabolites and their associated pathways.

The relationship between temperament with nutritional status and anthropometric measurements in adult individuals.

Interest in studies examining the effect of temperament types on nutrition has recently increased. The aim of this study was to evaluate the relationship between nine types of temperament, anthropometric measurements, and nutrition in adults. This study was conducted on 1317 individuals aged between 18 and 55 years.

Iristectorin A Ameliorates Cisplatin-Induced Hepatorenal Injury in Mice Through Modulation of the Nrf2/HO-1 Signaling Pathway.

Cisplatin (CIS) is a chemotherapeutic agent frequently used in cancer treatment. However, depending on the dosage and duration of use, CIS can lead to hepatotoxicity and nephrotoxicity. Iristectorin A (IRIS), a natural flavonoid, has been found to exhibit antioxidant and protective effects.

Safety and efficacy of supraciliary dexamethasone implantation for macular oedema: a preliminary comparative study.

Purpose: To evaluate the efficacy and safety of dexamethasone implantation in the supraciliary (SC) space, a novel and potential effective implantation site, compared to intravitreal (IV) application.

Methods: This prospective study included 39 eyes of 38 patients with macular oedema (ME) who underwent SC and IV dexamethasone implantation (SC-DEX and IV-DEX). Patients were randomly assigned to treatment groups and followed for 3 months.

The evaluation of internal adaptation of glass ionomer restorations applied after the use of different cavity conditioners in primary teeth: an in-vitro study.

Background: This study aimed to comparatively evaluate the effects of different cavity conditioners on internal adaptation (IA) of glass ionomer-based restorative materials applied to primary teeth.

Methods: 80 extracted primary second molar teeth were randomly assigned to four different cavity conditioner groups [10% polyacrylic acid, 20% polyacrylic acid, 17% ethylene diamine tetraacetic acid (EDTA), 35% phosphoric acid]. Class V cavities were prepared on the buccal surfaces and relevant cavity conditioners were applied, and the samples in each cavity conditioner group were randomly assigned to glass hybrid (GHR) or conventional glass ionomer restoratives (CGIR).

Postprocedural Contrast-Associated Acute Kidney Injury and Prognosis of Patients Undergoing Recanalization of Chronic Total Occlusions.

Percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs) requires advanced techniques and prolonged procedural efforts, often necessitating high contrast volumes, which may increase the risk of contrast-associated acute kidney injury (CA-AKI). However, evidence suggests that factors beyond contrast exposure contribute to CA-AKI, though data specific to CTO PCI remain limited. Patients undergoing contemporary CTO PCI at our university-affiliated tertiary care center were enrolled.

Analyzing the Effect of Factors on Individuals' Subjective Well-Being with Quantile Bayesian Structural Equation Modeling Approach.

This study investigates factors influencing individuals' levels of subjective well-being by examining fundamental variables, called life domains, such as satisfaction with health, education, marriage, housing district, work life, social life, relationships, and public services. The aim is to understand how these domains affect various quantile values of subjective well-being. To achieve this, the Life Satisfaction Survey dataset for 2020, obtained from the Turkish Statistical Institute, was utilized, and Bayesian Quantile Structural Equation Modeling and Bayesian Structural Equation Modeling methods were applied.

Aggression in crime and sports: a study on prisoners and amateur combat athletes in Türkiye.

Background: This research focuses on examining and comparing the aggression levels of prisoners incarcerated for intentional injury and amateur combat athletes. The study aims to explore the differences in aggression levels among these groups to understand the impact of incarceration and sports participation on aggression.

Methods: The participants included in the analysis consist of prisoners (n = 363) housed in Marmara No.

A Newly Synthesized Benzimidazolium Salt: 1-(2-Cyanobenzyl)-3-(4-Vinylbenzyl)-1H-Benzo[D]imidazol-3-ium Chloride as a Potential Anticancer Agent for Colon Cancer Treatment, In Vitro Study.

Colon cancer is one of the most common cancer-related deaths. Drug resistance is one of the biggest challenges in cancer treatment. Numerous pharmacological and biochemical investigations have documented the benzimidazole ring's anticancer, anti-inflammatory, and antioxidant properties.

Turkish adapration of "Simulation-Based interprofessional Teamwork Assessment Tool": SITAT-TR.

Inroduction: The Simulation-based Interprofessional Teamwork Assessment Tool (SITAT) is a valuable instrument for evaluating individual performance within interprofessional teams.

Aim: This study aimed to translate and validate the SITAT into Turkish (SITAT-TR) to enhance interprofessional education and teamwork assessments in the Turkish context.

Methods: This study was designed as an adaptation study in a descriptive research design.

Strongyloides stercoralis infection in a patient initiating corticosteroid therapy for hypereosinophilia: A case report.

Strongyloides stercoralis (S. stercoralis) is a soil-transmitted nematode that is endemic to tropical and subtropical regions. S.

[Multicentric Screening of Local Antibiotic Resistance in Uncomplicated Urinary System Infections: 1850 Patients from 37 Centers].

This study was aimed to identify the most frequently observed pathogens in uncomplicated urinary tract infections from outpatient urinary isolates obtained across seven different geographical regions in Türkiye and to determine whether the antibiotic resistance rates of these pathogens differ significantly between these regions. The study included patients aged 18 to 65 years who were diagnosed with uncomplicated urinary tract infections and had positive urine cultures from March 2021 to August 2022, across 37 different centers in Türkiye. The participating centers were selected based on their use of the disk diffusion method, in line with the European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines, to ensure standardization of urine culture data.

SARS-CoV-2 immune responses in patients with multiple myeloma and lenalidomide maintenance therapy.

Introduction: Multiple myeloma (MM) is an uncontrolled plasma cell proliferation in the bone marrow, leading to immune dysregulation with impaired humoral immune responses. Conversely, cellular-based responses play a vital role in MM patients. However, the extent and duration of cellular-induced protection remain unclear to date.

Fractal analysis of jawbone structure in patients with rheumatoid arthritis.

Purpose: Periarticular and generalized osteoporosis are well-known comorbidities of rheumatoid arthritis (RA), associated with either the disease itself or glucocorticoid therapy. This study was performed to quantitatively evaluate changes in the jawbones of patients with RA using fractal analysis (FA).

Materials And Methods: The study comprised 186 participants, including 144 women and 42 men.