115 results match your criteria: "Rutgers New Jersey Medical School Newark[Affiliation]"

Objectives: While it is known that surgical costs continue to rise in the United States, there is little information about the specific underlying factors for this variation in many common procedures. This study investigates the influence of geographic location and hospital demographics on hospital cost and postoperative outcomes in adult patients undergoing total thyroidectomy (TT).

Methods: The National Inpatient Sample was queried for patients who underwent primary TT between 2016 and 2017.

View Article and Find Full Text PDF

Purpose: Chat Generative Pre-Trained Transformer (ChatGPT) may have implications as a novel educational resource. There are differences in opinion on the best resource for the Orthopaedic In-Training Exam (OITE) as information changes from year to year. This study assesses ChatGPT's performance on the OITE for use as a potential study resource for residents.

View Article and Find Full Text PDF

Objectives: Auditory brainstem response (ABR) is the gold standard to assess hearing loss in pediatric patients. Multiple widely accepted ABR protocols with varying parameters are accepted, difference in standards may lead to misdiagnosis or delay in diagnosis and treatment. This study investigates the quality of ABR testing in pediatric patients in addition to changes in diagnoses and management.

View Article and Find Full Text PDF

Introduction: Exosomes are extracellular vesicles that transport bioactive substances during normal and abnormal cellular physiological processes. The unique properties of exosomes can be exploited for use as biomarkers and targeted drug delivery vehicles, and are, for this reason, gaining increasing attention in the field of dermatology. This review aims to synthesise the existing evidence supporting exosomes in regenerative and cosmetic dermatology.

View Article and Find Full Text PDF

Inflammatory bowel disease (IBD), which encompasses ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory condition of the gastrointestinal (GI) tract that presents complex diagnostic and management challenges. Early detection and treatment of IBD is paramount, as IBD can present with serious complications, including bowel perforation, arthritis, and colorectal cancer. Most forms of diagnosis and therapeutic management, like ileocolonoscopy and upper endoscopy are highly invasive and require extensive preparation at great discomfort to patients.

View Article and Find Full Text PDF

Objectives: Congenital laryngomalacia (CLM) is the most common cause of stridor in neonates and is commonly associated with reflux disease (RD) such as gastroesophageal reflux and newborn esophageal reflux. This study investigates the impact of RD on the management and outcomes of neonates with CLM.

Methods: The 2016 Kids' Inpatient Database (KID) was queried for neonates with CLM (ICD-10: Q31.

View Article and Find Full Text PDF

Objective: Surgical resection is associated with higher overall survival (OS) than definitive radiotherapy (RT) or chemoradiotherapy (CRT) in cT4b sinonasal squamous cell carcinoma (SCC). Our study investigates the survival benefit of surgical resection in cT4b sinonasal non-SCC.

Methods: The 2004 to 2019 National Cancer Database was queried for patients with cT4b sinonasal non-SCC undergoing definitive treatment with (1) surgical resection + additional therapy (RT, chemotherapy, or both), (2) RT alone, or (3) CRT.

View Article and Find Full Text PDF

Objective: Retrograde cricopharyngeal dysfunction (R-CPD) is a syndrome with rapidly increasing awareness since being first described in March 2019. As such, few cases of R-CPD are currently reported in the literature. The goal of this study is to provide a comprehensive systematic review of the available literature on R-CPD, including patient characteristics, diagnosis, and management.

View Article and Find Full Text PDF
Article Synopsis
  • - Pemphigus is a serious autoimmune blistering disease that significantly impacts patients' health and quality of life, prompting numerous clinical trials to explore effective treatments.
  • - A review of 53 randomized clinical trials showed that the Pemphigus Disease Area Index is the most commonly used disease severity measure, particularly gaining traction after 2015, while less popular methods have declined.
  • - There's a growing trend toward including Quality of Life (QoL) measurements in clinical trials, although only a quarter currently assess it; standardizing these measures can improve data interpretation and clinical relevance over time.
View Article and Find Full Text PDF

Perceptions, realities, and alternatives in rescue epinephrine.

Ann Allergy Asthma Immunol

December 2024

Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

View Article and Find Full Text PDF

Objective: To investigate primary site surgical resection and overall survival (OS) in clinically distantly metastatic (cM1) oral cavity squamous cell carcinoma (OCSCC).

Methods: The 2006-2018 National Cancer Database was queried for patients presenting with cM1 OCSCC who underwent chemotherapy. Binary logistic, Kaplan-Meier, and multivariable Cox proportional hazards regression models were implemented.

View Article and Find Full Text PDF

Objectives: Artificial intelligence is evolving and significantly impacting health care, promising to transform access to medical information. With the rise of medical misinformation and frequent internet searches for health-related advice, there is a growing demand for reliable patient information. This study assesses the effectiveness of ChatGPT in providing information and treatment options for chronic rhinosinusitis (CRS).

View Article and Find Full Text PDF

The Journal of Trauma and Acute Care Surgery: Emergency General Surgery Algorithms Article Series.

J Trauma Acute Care Surg

October 2024

From the Riverside University Health System Medical Center, Comparative Effectiveness and Clinical Outcomes Research Center (CECORC), 26520 Cactus Ave, CPC Building, Suite 102-5 Moreno Valley, CA 92555 (R.C.); Department of Surgery, Brigham and Women's Hospital (A.S.); Department of Surgery, University of South Florida Morsani College of Medicine (J.D.); Scripps Memorial Hospital La Jolla (W.L.B.); Weill Cornell Medicine (R.W.); Dept. of Surgery, University of Michigan School of Medicine (L.N.); Department of Surgery, University of California San Diego School of Medicine (T.C.); Department of Surgery, Rutgers New Jersey Medical School Newark (D.H.L.); Trauma Surgery & Surgical Critical Care, University of Southern California (K.I.).

View Article and Find Full Text PDF
Article Synopsis
  • Celiac disease (CD) is linked to a decreased risk of serious complications and mortality in patients with acute pancreatitis (AP), according to a recent analysis of over 2.25 million inpatient cases from 2016 to 2019.
  • The study found that patients with CD experienced significantly lower odds of adverse outcomes like sepsis and organ failure, but they were at a heightened risk for deep vein thrombosis and hypotensive shock.
  • Overall, patients with CD had shorter hospital stays and incurred lower medical costs during their treatment for AP, suggesting better outcomes compared to non-CD patients.
View Article and Find Full Text PDF
Article Synopsis
  • The study analyzed emergency department patients with documented heroin overdoses to determine the presence of fentanyl and its analogs.
  • Findings revealed that 88% of those who claimed to have used heroin had fentanyl or a fentanyl analog in their system, while only 27% actually had heroin detected.
  • The results indicate a significant discrepancy between the opioids patients thought they were using and what was actually found, suggesting that clinicians should assume fentanyl involvement in all opioid overdoses.
View Article and Find Full Text PDF
Article Synopsis
  • Rhinoscleroma is a chronic disease typically affecting the nose and nasopharynx, but in this case report, it presented with tracheal lesions as the first sign in an 88-year-old male.
  • The patient experienced longstanding dysphonia, and examinations revealed tracheal and sinus abnormalities, with biopsy confirming the presence of rhinoscleroma.
  • There is a lack of extensive literature on rhinoscleroma, especially in nonendemic regions, highlighting the need for thorough evaluation of unusual airway lesions to include rare conditions in the diagnosis.
View Article and Find Full Text PDF

Objective: Evaluate the quality of responses from Chat Generative Pre-Trained Transformer (ChatGPT) models compared to the answers for "Frequently Asked Questions" (FAQs) from the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) Clinical Practice Guidelines (CPG) for Ménière's disease (MD).

Study Design: Comparative analysis.

Setting: The AAO-HNS CPG for MD includes FAQs that clinicians can give to patients for MD-related questions.

View Article and Find Full Text PDF

Objective: To analyze current standards in urethroplasty by urologists employing buccal mucosal grafts (BMG) for treating urethral stricture disease (USD).

Methods: An IRB-approved online survey was distributed to members of the Society of Genitourinary Reconstructive Surgeons (GURS) between July and October 2022 to assess BMG utilization in urethroplasty. Questions covered surgeon experience, graft harvest site, graft length, surgical technique, and perceived success rates.

View Article and Find Full Text PDF

Objectives: Retraction of publications is critical to maintaining scientific integrity, yet there is a lack of research on its occurrence in Otolaryngology. This study investigates characteristics, trends, and reasons for retraction of publications in otolaryngology journals.

Study Design: Bibliometric analysis.

View Article and Find Full Text PDF

Purpose: Since its release in November 2022, Chat Generative Pre-Trained Transformer 3.5 (ChatGPT), a complex machine learning model, has garnered more than 100 million users worldwide. The aim of this study is to determine how well ChatGPT can generate novel systematic review ideas on topics within spine surgery.

View Article and Find Full Text PDF
Article Synopsis
  • This text indicates that there is a correction issued for the article with the DOI 10.1002/emp2.13143.
  • It implies that there were errors or inaccuracies in the original article that need to be addressed.
  • The correction is necessary for ensuring the accuracy and reliability of the published work.
View Article and Find Full Text PDF

A pseudoaneurysm results from a tear in a vessel wall. This leads to extravasation of blood into adjacent tissue and eventual formation of a fibrous sac that maintains continuity with the lumen. These vascular injuries very rarely occur in deeper vessels of the face (e.

View Article and Find Full Text PDF

Key Clinical Message: High-dose intravenous immunoglobulin exhibits great potential in the treatment of Netherton syndrome.

Abstract: Netherton syndrome (NS) is a rare autosomal recessive genodermatosis (OMIM #256500) characterized by superficial scaling, atopic manifestations, and multisystemic complications. It is caused by loss-of-function mutations in the SPINK5 gene, which encode a key kallikrein protease inhibitor.

View Article and Find Full Text PDF