State of the nonspecific component of the immune system during combination therapy for experimental bile peritonitis.

Combined use of sodium hypochlorite and intravenous laser irradiation of the blood in the postoperation therapy of 24-h bile peritonitis improved recovery of engulfing and digestive activity of neutrophilic granulocytes in the early postoperation period. Enzyme activity of neutrophilic granulocytes in earlier postoperation periods returned to normal after treatment with sodium hypochlorite alone.

Effect of sodium hypochlorite and UV irradiation of the blood on fluid and electrolyte balance, metabolism of lipids and proteins, and state of cell plasma membranes during experimental bile peritonitis.

We compared the normalizing effects of various methods of hemocorrection on homeostasis in animals with bile peritonitis. Combined treatment with hypochlorite and UV irradiation produced a potent membrane-stabilizing effect and increased adaptability of erythropoiesis.

Water-electrolyte balance, lipid and protein metabolism, and state of cell plasma membranes during experimental bile peritonitis.

The development of experimental bile peritonitis was accompanied by a variety of homeostatic changes. The disease is characterized by a specific clinical and laboratory syndrome.

Comparative pre- and postoperative results analysis of functional state of the esophagus assessment in patients with various stages of achalasia.

Objective: The aim of this study was to evaluate main results of morpho-functional state of the esophagus assessment in patients with various stages of achalasia before and after surgical treatment.

Methods: Between 1993 and 2002, a total of 65 patients with achalasia (26 males, 39 females; mean age 44.5+/-14.

[Pancreatic exocrine secretion in experimental acute postoperative pancreatitis].

Transformations of parameters of pancreatic exocrine secretion after the direct operations on the pancreas of a dog were studied during the experiment. It was determined that the early post-operative period proceeds in the conditions of the expressed pancreatic hypersecretion, hyperenzymemia and ductal hypertension. Their intensity reduces as the destructive process in pancreas develops.

[Morphofunctional organization of pancreatic secretory activity (a new paradigm)].

This is a review of physiological, morphological and clinical studies of pancreas secretion with the emphasis placed on pancreatic enzymes. It was established that different parts of the duodenal mucous coat have different chemosensory thresholds to the stimulators and inhibitors of pancreatic secretion. Secretory regions of the pancreas having a modular organization are also functionally different.

[Local arterial hypertension in the pathogenesis of ulcers and chronic pancreatitis].

Local arterial hypertension is a morphological and functional phenomenon representing a change of the arterial channel, which is observed in a restricted part of an organ being as large as the blood supply pool of a large artery, or the pool of a separate artery. No demonstrative explanation has been found for these vascular channel changes similar to the widespread ones that are observed in case of systemic hypertension until now.

[Crystallo-optic structures of bile in chronic acalculous cholecystitis].

A crystal optical study of the cystic bile under the conditions of compulsory dehydration in patients with acalculous cholecystitis made it possible to determine selective markers of lithogenic dyscholia according to the bile oversaturation with cholesterol, bilirubin and calcium. Chronic acalculous cholecystitis (CAC) is a chronic polyetiologic inflammatory disease of the gall-bladder (GB) combined with motor-tonic impairments of the bile-excreting tract function and with changes of physical and chemical properties and biochemical bile structure (dyscholia). CAC contributes to cholestasia, metabolic disorders and formation of calculi.

[Surgical treatment of complicated peripapillary duodenal ulcer].

Ulcerative gastroduodenal bleedings have remained one of the most complicated problems of emergency abdominal surgery up to the present. According to the literature, they make up approximately one half of all gastroduodenal bleedings and are accompanied by high lethality--from 10 to 30%. At that the highest percentage of lethality falls at elderly and old patients.