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Physiol Rep
January 2015
I. M. Sechenov First Moscow State Medical University, Moscow, Russia Petrovsky Russian Research Center of Surgery, RAMS, Moscow, Russia.
The Brugada syndrome (BrS) is an inherited arrhythmia characterized by ST-segment elevation in V1-V3 leads and negative T wave on standard ECG. BrS patients are at risk of sudden cardiac death (SCD) due to ventricular tachyarrhythmia. At least 17 genes have been proposed to be linked to BrS, although recent findings suggested a polygenic background.
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