2 results match your criteria: "Russia Institute of Protein Research[Affiliation]"

We have created a new server FoldHandedness. Using this server it is possible: (i) to define the regions of helices from two issues (from the PDB file and using the last version of the DSSP program), (ii) to determine the handedness for any chosen three helices and (iii) to calculate the angle and sign between the chosen pairs of the helices for large proteins and complexes of proteins with DNA or RNA.

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Ste20-like protein kinase SLK (LOSK) regulates microtubule organization by targeting dynactin to the centrosome.

Mol Biol Cell

October 2013

A. N. Belozersky Institute for Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119991, Russia Institute of Gene Biology, Russian Academy of Sciences, Moscow 119334, Russia Institute of Protein Research, Russian Academy of Sciences, Moscow 117334, Russia.

The microtubule- and centrosome-associated Ste20-like kinase (SLK; long Ste20-like kinase [LOSK]) regulates cytoskeleton organization and cell polarization and spreading. Its inhibition causes microtubule disorganization and release of centrosomal dynactin. The major function of dynactin is minus end-directed transport along microtubules in a complex with dynein motor.

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