Comparison of toric intraocular lens alignment between femtosecond laser-assisted capsular marking and digital marking.

Purpose: To compare the accuracy of toric intraocular lens (IOL) alignment between femtosecond laser-assisted capsular marking and digital marking.

Setting: Ruhr University Eye Clinic, Bochum, Germany.

Design: Prospective clinical trial.

The Blue Light Hazard Versus Blue Light Hype.

Purpose: The blue light hazard is the experimental finding that blue light is highly toxic to the retina (photic retinopathy), in brief abnormally intense exposures, including sungazing or vitreoretinal endoillumination. This term has been misused commercially to suggest, falsely, that ambient environmental light exposure causes phototoxicity to the retina, leading to age-related macular degeneration (AMD). We analyze clinical, epidemiologic, and biophysical data regarding blue-filtering optical chromophores.

Ab externo device for the treatment of glaucoma: direct flow from the anterior chamber to the ocular surface.

A new microinvasive glaucoma surgery device, the Beacon Aqueous Microshunt (BAM), drains aqueous humor directly from the anterior chamber to the surface of the eye vs draining to enclosed spaces within the eye, where outflow resistance, including the episcleral venous pressure, might limit drainage effectiveness. The BAM has a 0.030 mm × 0.

Long-term follow-up and clinical evaluation of the light-adjustable intraocular lens implanted after cataract removal: 7-year results.

Purpose: To determine the long-term safety and effectiveness of a light-adjustable intraocular lens (LAL) over a period that is longer than reported in the literature at the time of the study.

Setting: University Eye Hospital, Bochum, Germany.

Design: Noninterventional observation.

Methods for the study of near, intermediate vision, and accommodation: an overview of subjective and objective approaches.

Purpose: To present an overview of contemporary methods and metrics used to measure near vision, intermediate vision, and accommodation.

Methods: A search in PubMed was performed with the following key phrases: near vision, intermediate vision, objective and subjective methods for the measurement of accommodation. For subjective methods, we included only those that are most widely used, had a scientific evidence of its outcomes, and have an easy availability at the doctor's office.

Photorefractive intrastromal corneal crosslinking for treatment of myopic refractive error: Findings from 12-month prospective study using an epithelium-off protocol.

Purpose: To assess the long-term effectiveness and safety of photorefractive intrastromal corneal crosslinking (CXL) in patients with low myopia.

Setting: Ruhr University Eye Hospital, Bochum, Germany.

Design: Prospective case series.

Safety of femtosecond laser-assisted primary posterior capsulotomy immediately after cataract surgery.

Purpose: To evaluate the safety and feasibility of a new femtosecond laser-assisted method for posterior capsule opacification (PCO) prevention.

Setting: University Eye Hospital Bochum, Bochum, Germany.

Design: Prospective randomized intraindividual case series.

Photorefractive intrastromal corneal crosslinking for the treatment of myopic refractive errors: Six-month interim findings.

Purpose: To evaluate the safety and efficacy of photorefractive intrastromal corneal crosslinking (CXL) in low myopia.

Setting: Ruhr University Eye Hospital, Bochum, Germany.

Design: Prospective case series.

Efficacy, Safety, and Risk Factors for Failure of Standalone Ab Interno Gelatin Microstent Implantation versus Standalone Trabeculectomy.

Purpose: To compare the efficacy, safety, and risk factors for failure of standalone ab interno gelatin microstent implantation with mitomycin C (MMC) versus trabeculectomy with MMC.

Design: International, multicenter, retrospective interventional cohort study.

Participants: Three hundred fifty-four eyes of 293 patients (185 microstent and 169 trabeculectomy) with no prior incisional surgery.

Greater vertical spot spacing to improve femtosecond laser capsulotomy quality.

Purpose: To evaluate the effect of adapted capsulotomy laser settings on the cutting quality in femtosecond laser-assisted cataract surgery.

Setting: Ruhr-University Eye Clinic, Bochum, Germany.

Design: Prospective randomized case series.

Clinical performance in continuous curvilinear capsulorhexis creation supported by a digital image guidance system.

Purpose: To test whether a default capsulorhexis diameter could be attained more precisely when manual continuous curvilinear capsulorhexis (CCC) creation was supported by a biomorphological detection unit.

Setting: Ruhr University Eye Hospital, Bochum, Germany.

Design: Prospective interventional study.

Cataract formation after YAG laser vitreolysis: importance of femtosecond laser anterior capsulotomies in perforated posterior capsules.

Purpose: To report a patient who developed a white cataract after Nd:YAG laser vitreolysis with a posterior capsule defect.

Methods: Femtosecond laser-assisted capsulotomy was performed for optic capture fixation in a patient with a cataract due to a posterior capsule defect after Nd:YAG laser-vitreolysis.

Results: A 55-year-old, highly myopic woman presented with visual impairment 4 days after Nd:YAG laser vitreolysis due to preexisting floaters.

Primary posterior capsulotomy in femtosecond laser-assisted cataract surgery: In vivo spectral-domain optical coherence tomography study.

Purpose: To evaluate whether the size of Berger space is safely predictable in patients having cataract surgery using 3-dimensional spectral-domain optical coherence tomographic (3-D SD-OCT) image analysis.

Setting: Ruhr University Eye Hospital, Bochum, Germany.

Design: Prospective interventional case series.

Systemic ocular antigen immunization leads only to a minor secondary immune response.

The immunization with optic nerve homogenate antigen (ONA) or S100 induced retinal degeneration. Since many neurological diseases are reinforced or initiated by immune cells, leucocytes were analyzed. CD3(+) T-cells in the retina increased slightly in ONA rats, but not in S100 treated retinas.

Laser-assisted marking for toric intraocular lens alignment.

Unlabelled: We describe a technique of 3-dimensional spectral-domain optical coherence tomography-controlled laser-assisted corneal marking for toric intraocular lens implantation. To facilitate accurate alignment, the technique creates 2 perpendicular intrastromal incisions (width 0.75 mm) using an image-guided femtosecond laser.

Retinal and Optic Nerve Damage is Associated with Early Glial Responses in an Experimental Autoimmune Glaucoma Model.

It is well established that the immunization with ocular antigens causes a retinal ganglion cell (RGC) decline, which is accompanied by glia alterations. In this study, the degenerative effects of the immunization with an optic nerve homogenate (ONA) and its purified compound S100 were analyzed on retinas and optic nerves. Since a participation of glia cells in cell death mechanisms is currently discussed, rats were immunized with S100 or ONA.

Femtosecond laser-assisted compared with standard cataract surgery for removal of advanced cataracts.

Purpose: To compare effective phacoemulsification time (EPT) for the removal of brunescent cataracts treated with femtosecond laser-assisted cataract surgery with standard cataract phacoemulsification techniques.

Setting: Ruhr University Eye Hospital, Bochum, Germany.

Design: Comparative prospective case study.

Early Clinical Results of a Novel Ab Interno Gel Stent for the Surgical Treatment of Open-angle Glaucoma.

Purpose: To evaluate the intraocular pressure (IOP) lowering effect of the XEN140 microfistula gel stent implant for the surgical treatment of open-angle glaucoma.

Patients And Methods: Forty-nine eyes of 49 patients with an IOP>18 mm Hg and ≤35 mm Hg were studied in a prospective nonrandomized multicenter cohort trial of the surgical implantation of the XEN140 implant in patients with open-angle glaucoma. Complete success was defined as a postoperative IOP≤18 mm Hg with ≥20% reduction in IOP at 12 months without any glaucoma medications.

Optic capture in complicated laser-assisted cataract surgery.

Unlabelled: An 84-year-old woman had routine laser-assisted cataract surgery with anterior laser capsulotomy and lens fragmentation. During hydropolishing of the posterior capsule, an unexpected posterior capsule rupture occurred without vitreous loss. The haptics of the intraocular lens (IOL) were implanted in the ciliary sulcus, and the IOL optic was fixated in the capsular bag by the anterior laser capsulotomy.

Correlation of Tear Film Osmolarity and 2 Different MMP-9 Tests With Common Dry Eye Tests in a Cohort of Non-Dry Eye Patients.

Purpose: Given that early-stage dry eye is difficult to diagnose, the purpose of this study was to evaluate the performance of matrix metalloproteinase 9 (MMP-9) and tear film osmolarity (TFO) in a cohort of elderly patients with potential dry eye disease (DED).

Methods: A group of 20 patients, aged 60 years and above, previously undiagnosed with DED were selected. The following DED tests were performed: tear osmolarity, MMP-9 (InflammaDry), Schirmer test, tear film break-up time, Ocular Surface Disease Index (OSDI) questionnaire, corneal fluorescein staining, and conjunctival lissamine green staining.

Femtosecond laser-assisted pediatric cataract surgery: Bochum formula.

Purpose: To assess capsulotomy enlargement after femtosecond laser treatment in pediatric cataract surgery and to assess the possible relationship to the patient's age.

Setting: Ruhr University Eye Hospital, Bochum, Germany.

Design: Prospective case series.

Histologic evaluation of in vivo femtosecond laser-generated capsulotomies reveals a potential cause for radial capsular tears.

Purpose: To compare histologically the size and appearance of capsule disks after femtosecond laser-assisted cataract surgery and conventional cataract surgery.

Methods: In 100 eyes of 100 patients with visually significant cataracts, a femtosecond laser capsulotomy or a capsulorhexis with an aimed diameter of 5.0 mm was performed by one experienced surgeon.