3 results match your criteria: "Royal Melbourne HospitalParkville[Affiliation]"
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AJNR Am J Neuroradiol
July 2024
Department of RadiologyThe University of MelbourneParkville, Victoria, Australia.
Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by and Its Outer Membrane Vesicles.
Front Cell Infect Microbiol
April 2018
Department of Medicine, University of Melbourne, Royal Melbourne HospitalParkville, VIC, Australia.
Article Synopsis
- The text discusses the bacterial species associated with periodontitis and its outer membrane vesicles (OMVs), which are thought to contribute to the bacteria's ability to cause disease.
- The study compares how macrophages, which are immune cells, respond to either the bacteria or its OMVs, with the latter causing greater immune mediator production and shifting macrophage metabolism to glycolysis.
- The findings highlight that while the bacteria do not activate inflammasomes leading to cell death, the OMVs do trigger significant inflammatory responses and cell death processes, suggesting their important role in chronic periodontitis pathology.
Impact of Mild Head Injury on Neuropsychological Performance in Healthy Older Adults: Longitudinal Assessment in the AIBL Cohort.
Front Aging Neurosci
May 2016
School of Psychology and Speech Pathology, Curtin UniversityPerth, WA, Australia; Health Department of WA, Neurosciences UnitPerth, WA, Australia.
Traumatic brain injury (TBI) is suggested to be a significant risk factor for dementia. However, little research has been conducted into long-term neuropsychological outcomes after head trauma. Participants from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing (AIBL) who had recovered after sustaining a mild TBI involving loss of consciousness more than 5 years previously were compared with matched controls across a 3-year period.
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