1 results match your criteria: "Royal Adelaide Hospital fEnvironment Protection Authority SA[Affiliation]"
Targeted α-therapy using 227Th-APOMAB and cross-fire antitumour effects: preliminary in-vivo evaluation.
Nucl Med Commun
December 2014
aTranslational Oncology Laboratory, Centre for Cancer Biology, SA Pathology bSchool of Medicine cSchool of Chemistry and Physics, University of Adelaide dDepartment of Medical Physics eCancer Clinical Trials Unit, Royal Adelaide Hospital fEnvironment Protection Authority SA, Adelaide, Australia.
Resistance to conventional cancer treatments is a major problem associated with solid tumours. Tumour hypoxia is associated with a poor prognosis and with poor treatment outcomes; therefore, there is a need for treatments that can kill hypoxic tumour cells. One potential option is targeted α-radioimmunotherapy, as α-particles can directly kill hypoxic tumour cells.
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