1 results match your criteria: "Rouen University Hospital-Charles Nicolle-France[Affiliation]"
Usefulness of the serum carcinoembryonic antigen kinetic for chemotherapy monitoring in patients with unresectable metastasis of colorectal cancer.
J Clin Oncol
August 2008
Hepato-Gastroenterology Department, Digestive Oncology Unit, Rouen University Hospital-Charles Nicolle-France, 1 rue de Germont, 76031 Rouen Cedex, France.
Purpose: The aim of the study was to evaluate the relationship between serum carcinoembryonic antigen (CEA) kinetic and response to chemotherapy in patients with unresectable metastasis of colorectal cancer.
Patients And Methods: The kinetic was calculated using the slope of an exponential-regressive curve connecting the semi-logarithmic values of CEA. Receiver operating characteristic (ROC) curves were drawn to select the CEA slope thresholds to define patients with progressive or responsive disease with the highest sensitivity, specificity, and diagnosis accuracy odds ratio (DOR).