649 results match your criteria: "Rothman Institute at Thomas Jefferson[Affiliation]"

Study Design: Retrospective cohort study.

Objective: To evaluate inpatient complication profiles of patients receiving neuromuscular blockade reversal via sugammadex versus neostigmine/glycopyrrolate.

Summary Of Background Data: Sugammadex is a neuromuscular blockade reversal agent that binds non-depolarizing muscle relaxants.

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Introduction: Bone Marrow Lesions (BMLs) have a strong correlation to patient reported pain, functional limitations, joint deterioration, and rapid progression to total knee arthroplasty. The Subchondroplasty® (SCP) Procedure uses AccuFill®, a calcium phosphate bone substitute material (BSM), to treat bone defects such as microtrabecular fractures and BML.

Methods: This observational, prospective, multicenter, cohort study evaluated the effect of the SCP Procedure at two-year follow-up for 70 patients with knee BML.

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Introduction: Cervical nerve palsies, most commonly C5, are relatively common following posterior cervical decompression and fusion (PCDF) for the management of cervical myelopathy. However, phrenic nerve palsy following PCDF is a rare complication documented in only one previous case report. The authors present a case of phrenic nerve palsy following PCDF.

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Surgeon Prescribing Patterns And Perioperative Risk Factors Associated With Prolonged Opioid Use After Total Shoulder Arthroplasty.

J Am Acad Orthop Surg

December 2024

From the Thomas Jefferson University School of Medicine, Philadelphia, PA (Pezzulo, Farronato, and Juniewicz), and The Rothman Institute at Thomas Jefferson University, Philadelphia, PA (Kane, Kellish, and Davis).

Introduction: The opioid epidemic in the United States has contributed to a notable economic burden and increased mortality. Total shoulder arthroplasty (TSA) has become more prevalent, and opioids are commonly used for postoperative pain management. Prolonged opioid use has been associated with adverse outcomes, but the role of surgeons in this context remains unclear.

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Study Design: Literature review with clinical recommendations.

Objective: To highlight important studies about osteoporotic spinal fractures (OF) that may be integrated into clinical practice based on the assessment of the AO Spine KF Trauma and Infection group key opinion leaders.

Methods: 4 important studies about OF that may affect current clinical practice of spinal surgeons were selected and reviewed with the aim of providing clinical recommendations to streamline the journey of research into clinical practice.

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Background: Distal one-third clavicle fractures are frequently unstable and often require surgical fixation due to high rates of nonunion. Many common methods of fixation have high rates of union but are associated with hardware discomfort and need for secondary surgery. The purpose of this study was to evaluate the outcomes of a fixation technique involving arthroscopically assisted open reduction internal fixation of unstable distal clavicle fractures via a coracoclavicular (CC) suspensory endobutton and cerclage tape.

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Article Synopsis
  • - The medial patellofemoral ligament (MPFL) plays a crucial role in preventing lateral patellar dislocation, and the study aims to compare the effectiveness of autograft versus allograft for MPFL reconstruction in terms of functional outcomes and recurrence rates.
  • - In a cohort study assessing patients who underwent MPFL reconstruction from 2013 to 2018, no significant differences were found in postoperative functional scores or rates of recurrent instability between the autograft and allograft groups.
  • - The research concluded that both graft types are effective options for MPFL reconstruction, as they demonstrated comparable patient outcomes in terms of pain and instability following the procedure.
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The abstract of a research paper functions to attract readers and highlight the clinical significance of a research project in a broadly appealing manner. Abstract structure is commonly dictated by the target journal, however, a basic style typically follows the "Introduction, Methods, Results and Discussion" structure of introduction, materials/methods, results, and discussion/conclusion. The abstract itself is commonly the initial accessible portion of a research paper, so writing in an engaging while informative manner is imperative for increasing manuscript views and citations.

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With the vast increase in spinal surgery research and accessibility, critical evaluation of studies is paramount. Historically, P values and confidence intervals have been the gold standard, but more recently, the inclusion of the Fragility Index has brought a more holistic approach. The Fragility Index aims to communicate the robustness of a trial and how tenuous statistical significance may be.

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Purpose: The AOSpine classification divides thoracolumbar burst fractures into A3 and A4 fractures; nevertheless, past research has found inconsistent interobserver reliability in detecting those two fracture patterns. This systematic analysis aims to synthesize data on the reliability of discriminating between A3 and A4 fractures.

Methods: We searched PubMed, Scopus, and the Web of Science for studies reporting the inter- and intra-observer reliability of detecting thoracolumbar AO A3 and A4 fractures using computed tomography (CT).

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Factors Related to Clinical Performance in Spine Surgery Fellowship: Can We Predict Success.

J Am Acad Orthop Surg

September 2024

From the Department of Orthopedic Surgery, Mayo Clinic, Rochester, MI (Levy, Currier, Huddleston, Nassr, Freedman, and Sebastian), the Department of Orthopaedic Surgery, Rothman Institute at Thomas Jefferson University, Philadelphia, PA (Boere, Bodnar, Paulik, Kurd, Rihn, Canseco, Schroeder, Kepler, Vaccaro, Hilibrand), and the Department of Orthopaedic Surgery, University of Utah, Salt Lake City, UT (Randell, Spina, Spiker, Lawrence, Brodke, Karamian).

Introduction: The factors most important in the spine fellowship match may not ultimately correlate with quality of performance during fellowship. This study examined the spine fellow applicant metrics correlated with high application rank compared with the metrics associated with the strongest clinical performance during fellowship.

Methods: Spine fellow applications at three academic institutions were retrieved from the San Francisco Match database (first available to 2021) and deidentified for application review.

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Article Synopsis
  • The study aimed to examine how resilience affects pain and neck disability outcomes in patients who had single- or double-level anterior cervical discectomy and fusion (ACDF).
  • Patients completed surveys on resilience, pain, and disability levels both before and after surgery, allowing researchers to categorize them based on their resilience levels.
  • Results showed that all patients improved post-surgery, but those with higher resilience reported better pain relief compared to those with lower resilience, indicating resilience may play a role in recovery outcomes.
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Background: Effective surgical wound management in total knee arthroplasty (TKA) is crucial for optimal healing and patient outcomes. Despite surgical advances, managing wounds to prevent complications remains challenging. This study aimed to identify and address evidence gaps in TKA wound management, including preoperative optimization, intraoperative options, and postoperative complication avoidance.

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Fractures involving the lunate facet of the distal radius (commonly called the volar ulnar corner or "critical corner") are often difficult to recognize radiographically. "Lunate facet escape" refers to the displacement of this fragment after attempted distal radius fracture closed or open reduction methods. Lunate facet escape can have severe consequences including carpal collapse with pain, instability, and arthritis.

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Background: Complex proximal interphalangeal joint (PIPJ) fractures are challenging injuries to treat. There are multiple established treatment methods available for these injuries, including dynamic external fixation. This study reports the outcomes of complex PIPJ fractures treated with a hand-specific external fixation device.

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Background: Severe acetabular bone loss encountered during revision total hip arthroplasty (THA) poses a clinical challenge. In cases involving pelvic discontinuity, where the ilium is separated superiorly from the inferior ischiopubic segment through the acetabulum, acetabular distraction may be used to restore the biomechanics of the hemipelvis. This technique allows for correct sizing of the acetabulum, and the subsequent peripheral distraction and medial compression at the discontinuity provide initial mechanical stability and biological fixation as bone in growth occurs.

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Background: Spontaneous rupture of the extensor pollicis longus (EPL) tendon following both nonoperative and operative treatment of distal radius fractures has been well described.

Purpose: The purpose of this study was to assess long-term outcomes of extensor indicis proprius to EPL tendon transfers for patients following distal radius fracture and EPL tendon repair.

Study Design: Retrospective case series focusing on long-term clinical outcomes.

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Background: This modified Delphi study aimed to develop a consensus on optimal wound closure and incision management strategies for total hip arthroplasty (THA). Given the critical nature of wound care and incision management in influencing patient outcomes, this study sought to synthesize evidence-based best practices for wound care in THA procedures.

Methods: An international panel of 20 orthopedic surgeons from Europe, Canada, and the United States evaluated a targeted literature review of 18 statements (14 specific to THA and 4 related to both THA and total knee arthroplasty).

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Case: Arteriovenous (AV) fistula in the ipsilateral extremity for hemodialysis presents unique challenges during shoulder arthroplasty. We describe 3 cases of shoulder arthroplasty performed through a deltopectoral approach on the ipsilateral side of an AV fistula. In all cases, the cephalic vein was found to be arterialized with increased diameter and thickness.

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Background: The purpose of this modified Delphi study was to obtain consensus on wound closure and dressing management in total knee arthroplasty (TKA).

Methods: The Delphi panel included 20 orthopaedic surgeons from Europe and North America. There were 26 statements identified using a targeted literature review.

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 Patients acutely infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may have increased risk for postsurgical pulmonary complications and mortality, particularly with general anesthesia. Surgery is often delayed to mitigate risk; however, excessive delays may result in morbidity. Optimal criteria for delaying surgery in patients with or without symptoms are unknown.

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Risk of noise-induced hearing loss in the spine surgeon.

N Am Spine Soc J

March 2024

The Rothman Institute at Thomas Jefferson University, Department of Orthopaedic Spine Surgery, 925 Chestnut St., Philadelphia, PA 19107, United States.

Background: Occupation-related noise-induced hearing loss (NIHL) has both negative economic and quality of life implications. The risk spine surgeons undertake in regards to NIHL during operative intervention is unknown. Governing bodies, including the National Institute for Occupational Safety and Health, have recommended exposure limits not to exceed 85 decibels (dB) over 8 hours.

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Electronic surveys are readily utilized for the conduction of orthopedic research and are commonly plagued by decreased response rates as compared with more conventional telephone and paper surveys. Given the rise of electronic survey usage and technological implementation into medical research, this paper aims to summarize factors both intrinsic and extrinsic which can increase survey completion in the clinical setting.

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Article Synopsis
  • Evidence-based medicine relies heavily on randomized control trials (RCTs) for medical decision-making, particularly in spinal surgery.
  • However, RCTs have several disadvantages specific to spinal surgery, prompting the use of other study designs.
  • This paper discusses various research methodologies, including observational studies like retrospective and prospective cohort studies, providing insights for researchers and practicing spine surgeons.
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