1,754 results match your criteria: "Ross University[Affiliation]"

Mucormycosis (zygomycosis) is a severe and often fatal mycotic infection affecting primarily immunocompromised individuals. A 61-year-old female with type 2 diabetes mellitus and end-stage renal disease developed septic shock in association with mucormycosis. Despite antifungal treatment with liposomal amphotericin B, the patient's condition rapidly deteriorated, leading to death within 48 hours.

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  • * Traditional methods of counting lymphocytes in intestinal biopsies have low reliability due to varying opinions among pathologists, prompting the development of an AI model for more consistent detection.
  • * The AI model shows high sensitivity and predictive value in identifying lymphocytes, potentially improving diagnostic accuracy for feline chronic enteropathy when supervised by a pathologist, despite some errors noted in specific cases.
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  • - Emphysematous hemorrhagic cystitis (EHC) is a rare and complicated urinary tract infection caused by gas-producing bacteria or fungi infecting the bladder wall, resulting in inflammation and reduced blood flow.
  • - The report details a case involving a 69-year-old man with various health issues, showcasing the difficulties in diagnosing and managing EHC.
  • - The study underlines the importance of quick identification and teamwork among healthcare providers to improve patient outcomes, particularly for those with pre-existing health problems.
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Jejunal diverticulosis is a rare form of diverticulosis characterized by acquired pseudodiverticula in the small bowel. Although most cases are asymptomatic, the condition can present diagnostic challenges due to its atypical presentation. Complications such as perforation can lead to acute abdomen, significantly increasing morbidity and mortality.

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Reproductive Risk Factor Patterns in Caribbean Women With Breast Cancer Across 4 Generations.

JAMA Netw Open

October 2024

Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, Miller School of Medicine, University of Miami, Miami, Florida.

Article Synopsis
  • Breast cancer is a common illness among women in the Caribbean, but not much is known about how their reproductive patterns affect when they get diagnosed.
  • A study was done to look at changes in these reproductive patterns and the age at which Caribbean women are diagnosed with breast cancer.
  • The study included over 1,000 women from various Caribbean countries, finding that younger women are more likely to start their periods earlier compared to older women.
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  • Morvan syndrome, or Morvan's fibrillary chorea, is a rare neurological condition linked to cancer, showing symptoms that affect the CNS, peripheral nerves, and autonomic functions.
  • A case study highlighted an adult female who suddenly experienced chest pain, weakness, and muscle spasms, revealing positive VGKC and amphiphysin antibodies in her blood.
  • The diagnosis of Morvan syndrome involves recognizing myokymia, positive VGKC antibodies, and neuropsychiatric symptoms, with this case demonstrating a unique link to amphiphysin positivity.
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Despite demonstrating the required competencies to graduate, many newly qualified doctors find the transition to internship difficult. There is a concern over whether their preparation is aligned with the expectations of the role. This study aimed to gain a better understanding of the competencies needed for legitimate practice as junior doctors and explores their perceived preparedness for practice.

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Psoriasis (PS) and inflammatory bowel disease (IBD) are immune-mediated chronic conditions that share pathophysiological processes, including immune system dysfunction, microbiome dysbiosis, and inflammatory pathways. These pathways result in increased turnover of epithelial cells and compromised barrier function. The assessment of the literature suggests that immunopathogenic mechanisms, such as tumor necrosis factor (TNF)-α signaling and IL-23/IL-17 axis dysregulation, are shared by PS and IBD.

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Schwannosis in the brain of a neonatal calf.

J Vet Diagn Invest

October 2024

Department of Population Medicine and Diagnostic Sciences, Cornell University, College of Veterinary Medicine, Ithaca, NY, USA.

Article Synopsis
  • Schwannosis is a rare condition involving abnormal growths of Schwann cells in the central nervous system, leading to partial myelination of nerve fibers.
  • A case study is presented of a 1-day-old Holstein-Friesian calf that had schwannosis in its brain and was submitted for autopsy due to deformities and early death.
  • Histological examination revealed specific markers indicating Schwann cell origin, and no signs of infectious disease were found, suggesting schwannosis should be considered in similar cases of calf deformities.
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New Clinical and Public Health Challenges in Vaccinations in US Adults.

Am J Med

September 2024

Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton; Departments of Medicine & Populations Health and Social Medicine, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton. Electronic address:

Article Synopsis
  • Rising recidivism is threatening the positive effects of vaccinations in the US, largely due to vaccine hesitancy and other complex factors.
  • The future looks promising thanks to advancements in vaccine technology and the commitment of healthcare professionals and public health systems, which are crucial for eliminating infectious diseases.
  • To effectively increase vaccination rates, healthcare providers must focus on rapid detection, isolation, and a comprehensive response strategy, including antiviral medications and social distancing measures.
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  • Parasites can adapt to exploit different host species, but little is known about their genetic evolution in natural settings with diverse hosts.
  • Researchers studied Bartonella bacteria in rodent populations in Israel to understand how they adapt when infecting different rodent species.
  • After infecting rodents, they found that specific genetic mutations dominated, particularly in a gene related to adhesion, indicating that these mutations could help the bacteria escape immune responses and evolve to better target specific hosts.
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  • Immune checkpoint inhibitors (ICIs) are used as a treatment for advanced cancers but can lead to pancreatitis, with an incidence of about 1-2%, particularly higher in combination therapies.
  • The review examines the connections between ICIs and pancreatitis, including clinical presentations, diagnosis, management strategies, and emphasizes the need for better understanding of underlying mechanisms and risk factors.
  • Current diagnosis relies on clinical symptoms and imaging, while management may involve IV fluids and pain control, with ongoing exploration of immunosuppressants for severe cases; long-term monitoring is necessary due to potential chronic issues.
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  • An 84-year-old woman with a past medical history of hypertension, diabetes, and hypothyroidism presented with a rapidly growing thigh mass, which was diagnosed as high-grade leiomyosarcoma that doubled in size within two weeks.
  • Following surgery and initiation of radiotherapy, she developed complications including respiratory distress and heart failure due to extensive metastatic disease and a pulmonary embolism.
  • The case emphasizes the difficulties in treating aggressive sarcomas in frail patients and suggests that earlier intervention with chemotherapy might have led to better outcomes, highlighting the importance of careful patient evaluation for cancer treatment options.
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Breaking down the concrete wall: Encouraging trickle-down allyship in plastic and reconstructive surgery training.

J Plast Reconstr Aesthet Surg

November 2024

Division of Plastic and Reconstructive Surgery, Department of Surgery, Mayo Clinic, Phoenix, AZ, USA; Division of Hand Surgery, Department of Orthopedic Surgery, Mayo Clinic, Phoenix, AZ, USA; Department of Neurosurgery, Phoenix, AZ, USA; Center for Humanities in Medicine, Mayo Clinic, Phoenix AZ, USA.

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Importance: Intermittent Explosive Disorder (IED) is an understudied psychiatric condition that presents with repeated episodes of impulsive aggression and poorly regulated emotional control, often resulting in interpersonal and societal consequences. Better understanding of comorbidities will allow for enhanced screening, diagnosis, and treatment of patients.

Objective: To investigate prevalence and associations of IED with psychiatric, neurological, and somatic disorders using real-world data.

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  • * Disseminated carcinomatosis of the bone marrow (DCBM) results in the spread of cancer cells in the bone marrow, causing serious blood disorders like thrombocytopenia (low platelet count).
  • * A unique case of a man in his late 50s showed acute thrombocytopenia as the first symptom, leading to a diagnosis of gastric cancer; despite chemotherapy, his condition worsened, highlighting the need for better diagnostic and treatment methods for DCBM.
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Sickle cell disease (SCD) is a hereditary hemoglobinopathy that can lead to progressive vasculopathy, increasing the risk of cerebrovascular complications. Moyamoya syndrome (MMS), a rare disorder characterized by stenosis of the internal carotid arteries, can occur in SCD patients due to chronic endothelial damage and inflammation. The coexistence of these conditions can result in severe cerebrovascular complications, presenting unique diagnostic and therapeutic challenges.

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  • An 88-year-old man with multiple health issues was diagnosed with metastatic pancreatic neuroendocrine carcinoma after experiencing significant weight loss, nosebleeds, and back pain.
  • The case highlights the need for using atypical tumor markers, like thyroid transcription factor 1, for diagnosis and stresses the value of a collaborative, patient-focused treatment strategy for managing these aggressive tumors.
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Porcine Teschoviruses (PTVs) are ubiquitous enteric viral pathogens that infect pigs and wild boars worldwide. PTVs have been responsible for causing the severe clinical disease (Teschen disease) to asymptomatic infections. However, to date, limited information is available on large-scale epidemiological data and molecular characterization of PTVs in several countries.

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This letter takes a unique approach to the complex relationship between criticism and constructive dialogue, specifically in response to issues raised by a recent original article publication. While criticism is often viewed negatively, this article uncovers its potential to stimulate meaningful and productive discussions, particularly in novel studies. By examining certain misinterpretations, the article aims to demonstrate how criticism, when approached with openness and respect, can deepen the understanding and appreciation of original works, and inspire future research on lecture playback speeds.

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  • - The study investigates the link between obesity and breast cancer characteristics in underserved populations in the U.S., focusing on safety-net hospitals.
  • - It analyzed data from 927 breast cancer patients, highlighting significant associations between body mass index (BMI), menopausal status, and disease stage at diagnosis, particularly in postmenopausal women.
  • - Findings indicated that obesity is associated with larger tumor sizes and more advanced lymph node involvement in postmenopausal patients, with higher obesity rates reported in African American patients.
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Background: The lymphatic microsurgical preventive healing approach reduces the risk of lymphedema after axillary lymph node dissection. We identified surgical factors of Lymphatic Microsurgical Preventive Healing Approach (LYMPHA) that influence lymphedema rates focusing on the vein caliber used.

Methods: A single-institution retrospective cohort study included breast cancer patients undergoing axillary lymph node dissection and LYMPHA (April 2021-November 2022) with a follow-up of at least 1 year.

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Minimally invasive surgery (MIS) provides superior results in the surgical treatment of inflammatory bowel disease (IBD). There exist various minimally invasive procedures, each possessing its own set of benefits and drawbacks. This literature review outlines these methodologies and underscores their importance in enhancing the outcomes of patients with IBD.

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Bleeding diathesis is an uncommon side effect of ibrutinib use and is seen in less than 5% of the population. We describe a case of an elderly woman with ibrutinib-induced spontaneous major extradural haematoma presenting as acute compressive myelopathy. She is a known case of splenic marginal zone lymphoma with multiple extramedullary relapses and presented to the emergency department with acute-onset low backache, followed by urinary retention.

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