5 results match your criteria: "Rome Eye Hospital[Affiliation]"

Deep Learning to Discriminate Arteritic From Nonarteritic Ischemic Optic Neuropathy on Color Images.

JAMA Ophthalmol

November 2024

Department of Neuro-Ophthalmology and Rothschild Neurovisual and Computational Sciences BRAIN Lab, Rothschild Foundation Hospital, Paris, France.

Article Synopsis
  • The study focuses on improving the diagnosis of arteritic anterior ischemic optic neuropathy (AAION) from giant cell arteritis, which can prevent vision loss, particularly when symptoms are subtle or unreliable tests are involved.
  • Researchers developed a deep learning system (DLS) to differentiate between AAION and nonarteritic anterior ischemic optic neuropathy (NAION) by analyzing color fundus images from a large international dataset involving 961 eyes from 802 patients.
  • The DLS demonstrated promising performance metrics, such as area under the receiver operating characteristic curve (AUC), sensitivity, specificity, and accuracy, validating its potential as a diagnostic tool during the acute phase.
View Article and Find Full Text PDF

We provide an overview of current macular imaging techniques and identify and describe biomarkers that may be of use in the routine management of macular diseases, particularly exudative age-related macular degeneration (AMD). This perspective includes sections on macular imaging techniques including optical coherence tomography (OCT) and OCT angiography (OCTA), classification of exudative AMD, and biomarkers in structural OCT and OCTA. Fluorescein angiography remains a vital tool for assessing the activity of neovascular lesions, while indocyanine green angiography is the preferred option for choroidal vessel imaging in neovascular AMD.

View Article and Find Full Text PDF

A 74-years-old man experienced severe diplopia one month after recovery from an uncomplicated SARS-CoV-2 infection. Neurological examination was normal whereas ophthalmological examination showed bilateral exophthalmos with a complex ocular motility disorder characterized by a pseudo-internuclear ophthalmoplegia after fatigue associated to impairment of elevation and infraduction. Antibodies against TSH and acetylcholine receptors were positive; subsequent hormonal tests, ultrasonography of thyroid gland, single fiber electromyography and orbit MRI confirmed the diagnosis of concomitant Graves Disease (GD) and Myasthenia Gravis (MG).

View Article and Find Full Text PDF

Purpose: To evaluate the morphological features and density of corneal subbasal plexus (SBP) using in vivo corneal confocal microscopy (IVCCM) in patients affected by Fuchs' endothelial corneal dystrophy (FECD) six months after Descemet membrane endothelial keratoplasty (DMEK) and Descemet-stripping automated endothelial keratoplasty (DSAEK).

Methods: We included patients affected by FECD, requiring corneal endothelial surgery due to corneal oedema occurred from 3 to 6 months. 7 eyes underwent DMEK and 7 eyes DSAEK.

View Article and Find Full Text PDF

Purpose: to study the clinical features of uveitis-glaucoma-hyphema (UGH) syndrome, particularly those useful for a differential diagnosis from unilateral hypertensive acute anterior uveitis.

Methods: A retrospective chart review was conducted on the clinical features of 9 patients with UGH syndrome. These features were then compared with those detected in 50 patients with unilateral hypertensive acute anterior uveitis.

View Article and Find Full Text PDF