Problematic definitions of Mobitz type II second degree AV block: Historical aspects.

Problems with the definition of type II second degree AV block are best understood by reviewing the historical aspects that include Mobitz's original description, the contributions of the Chicago Arrhythmia School and the growing importance of excluding slowing of the sinus rhythm.

Definition by FSH, AMH and embryo numbers of good-, intermediate- and poor-prognosis patients suggests previously unknown IVF outcome-determining factor associated with AMH.

Background: Though outcome models have been proposed previously, it is unknown whether cutoffs in clinical pregnancy and live birth rates at all ages are able to classify in vitro fertilization (IVF) patients into good-, intermediate- and poor prognosis.

Methods: We here in 3 infertile patient cohorts, involving 1247, 1514 and 632 women, built logistic regression models based on 3 functional ovarian reserve (FOR) parameters, including (1) number of good quality embryos, (2) follicle stimulating hormone (FSH, mIU/mL) and (3) anti-Müllerian hormone (AMH, ng/mL), determining whether clinical pregnancy and live birth rates can discriminate between good, intermediate and poor prognosis patients.

Results: All models, indeed, allowed at all ages for separation by prognosis, though cut offs changed with age.