6 results match your criteria: "Robert Wood Johnson Medical School at Rutgers University[Affiliation]"

Microvascular Inflammation of Kidney Allografts and Clinical Outcomes.

N Engl J Med

October 2024

From Université Paris Cité, INSERM Unité 970, Paris Institute for Transplantation and Organ Regeneration (M.S., A.S., M. Raynaud, V.G., G.D., D.Y., J.H., C. Legendre, O.A., C. Lefaucheur, A.L.), the Department of Pathology, Bichat Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP) (A.S.), the Kidney Transplant Department (G.D., C. Lefaucheur) and the Department of Pathology (J. Verine), Saint-Louis Hospital, AP-HP, the Department of Pathology, Necker Hospital, AP-HP (M. Rabant), the Division of Pediatric Nephrology, Necker Hospital, AP-HP, Université Paris Cité (O. Boyer), the Department of Kidney Transplantation, Necker Hospital, AP-HP (M.T., C. Legendre, D.A., O.A., A.L.), and the Division of Pediatric Nephrology, Robert Debré Hospital, AP-HP (J.H.), Paris, the Departments of Pediatric Nephrology (M.F.) and Nephrology (M.L.Q.), Centre Hospitalier Universitaire (CHU) Montpellier, Montpellier, the Pediatric Nephrology Department, Hôpital Universitaire Mère-Enfant, Hospices Civils de Lyon (HCL) (A.-L.S.-L.), and the Department of Transplantation, Edouard Herriot University Hospital, HCL, University of Lyon I (E.M.), Lyon, the Department of Nephrology-Dialysis-Transplantation, CHU de Toulouse, Toulouse (A.B., N.K.), Nantes Université, CHU Nantes, INSERM, Center for Research in Transplantation and Translational Immunology, Unité Mixte de Recherche 1064, Institute of Urology-Nephrology Transplantation of the University Hospital of Nantes, Nantes (R.D., M.G., P.-A.G., S.B.), and the Departments of Pathology (B.C.) and Nephrology, Transplantation, Dialysis, and Apheresis (L.C.), CHU Bordeaux, Bordeaux - all in France; the Division of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health (B.C.A.), and the Department of Pathology, University of Wisconsin (A.A., W.Z.) - both in Madison; Pediatric Nephrology, David Geffen School of Medicine at UCLA, UCLA Mattel Children's Hospital (P.W.), and Cedars-Sinai Comprehensive Transplant Center (E.H.) - both in Los Angeles; the Department of Pediatrics, University of Washington School of Medicine, Seattle Children's Hospital, Seattle (J.S.); the Division of Pediatric Nephrology, Emory University School of Medicine, Children's Pediatric Institute, Atlanta (R.G.); the Division of Pediatric Nephrology, University of Kansas City, Children's Mercy Hospital, Kansas City, MO (B.A.W.); the Division of Pediatric Nephrology and Hypertension, University of Tennessee Health Science Center, Le Bonheur Children's Hospital, Memphis (R.S.Z.); the Acute Dialysis Units, Pediatric Kidney Transplant, Medical University of South Carolina, Charleston (K.T.); the Division of Pediatric Nephrology, Hypertension, and Apheresis, Washington University School of Medicine and St. Louis Children's Hospital, St. Louis (V.R.D., R.S.D.); the Department of Pediatrics, Robert Wood Johnson Medical School at Rutgers University, New Brunswick, NJ (V.R.D.); the Department of Pediatrics I, University Children Hospital Heidelberg, Heidelberg (B.T.), and the Department of Nephrology and Critical Care Medicine, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Berlin Institute of Health, Berlin (R.A.C., K.B.) - both in Germany; the Division of Abdominal and Transplantation Surgery, Department of Surgery, Faculty of Medicine, Geneva University Hospitals (T.B.), and the Division of Transplantation Immunology, University Hospital of Geneva (J. Villard), Geneva, and the Division of Clinical Pharmacology, Department of Medicine, and the Department of Laboratory Medicine and Pathology, Lausanne University Hospital, Faculty of Medicine, University of Lausanne, Lausanne (F.R.G.) - all in Switzerland; and the Department of Nephrology and Kidney Transplantation, Vall d'Hebrón University Hospital, Barcelona (O. Bestard).

Background: The heterogeneous clinical presentation of graft microvascular inflammation poses a major challenge to successful kidney transplantation. The effect of microvascular inflammation on allograft outcomes is unclear.

Methods: We conducted a cohort study that included kidney-transplant recipients from more than 30 transplantation centers in Europe and North America who had undergone allograft biopsy between 2004 and 2023.

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Tele-assessment of autism in early childhood has increased. However, it is unclear how autism screening tools (M-CHAT-R, DCI) function as part of tele-assessment and relate to a commonly used tele-assessment instrument, the TAP. 361 families from a clinically referred sample of children (mean age: 27.

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The Mycobacterium tuberculosis genome contains an unusually high number of toxin-antitoxin modules, some of which have been suggested to play a role in the establishment and maintenance of latent tuberculosis. Nine of these toxin-antitoxin loci belong to the mazEF family, encoding the intracellular toxin MazF and its antitoxin inhibitor MazE. Nearly every MazF ortholog recognizes a unique three- or five-base RNA sequence and cleaves mRNA.

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Myxobacteria have been shown to produce a peculiar RNA-DNA complex called msDNA, in which a single-stranded DNA is branched out from a RNA molecule (msdRNA) by a 2',5' phosphodiester linkage. It has been predicted that reverse transcriptase is required for msDNA biosynthesis. We identified a gene for reverse transcriptase in M.

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msDNA is a peculiar molecule consisting of a branched RNA linked to single-stranded DNA via a 2',5' phosphodiester bond. A cell-free system, utilizing cells permeabilized with phenethyl alcohol, was established to study the synthesis of msDNA in M. xanthus.

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